Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 3603-3607 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The source resistance of a heterojunction field-effect transistor (HFET), whose reduction is mandatory for high-performance devices, consists of an ohmic contact resistance and an access resistance. The access region is located between the geometrical source and the geometrical source side of the gate contact. By means of a quantum-mechanical modeling program, the effect of changes in layer structure in the access region of a HFET is studied. A new heterojunction structure using a Si planar doped layer is designed to improve the linearity and reduce the access resistance by more than ten times for a specific transistor layout. Thanks to the higher sensitivity of the modeling program to structural information, the contribution of the tunneling current and the change of equilibrium as a function of temperature is investigated. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 89 (2001), S. 590-595 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A spatially discrete grain-boundary model for characterizing polycrystalline-silicon (poly-Si) thin-film transistors (TFTs) is developed. This model was formulated for an interface state localized at the grain boundary. Threshold voltage (Vth) variation was analyzed using the model by changing the trap density and the location and number of grain boundaries in the poly-Si channel. The Vth shifts were found to be linearly dependent on the trap density (NGB) at the grain boundary and almost independent of the boundary location. The dependence of Vth on NGB was 0.15 V per trap density of 1012 cm−2 in long-gate TFTs. Since grain formation in the poly-Si channel is not controllable (it tends to be random), the threshold-voltage shift (ΔVth) predicted by the simulation will appear as statistical fluctuation in device fabrication. Simulation of the Vth fluctuation ranges showed that ΔVth increases with a decrease in channel length and will exceed 0.2 V in TFTs with a channel length of 1 μm or less when there is one grain boundary in the channel region and the trap density is 1012 cm−2. However, adding a moderately doped p region near the source in an n-channel TFT will suppress threshold-voltage fluctuation, even when the grain formation is uncontrollable, as we have theoretically demonstrated through simulation. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 87 (2000), S. 8064-8069 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Anomalous currents (I) in worst-bit cells in high-density dynamic random-access memories are theoretically analyzed with temperature (T) as a parameter. And activation energy (Ea) is evaluated from the slopes of (log I) versus (1/T) plots. It is found that the anomaly in Ea as a function of applied bias (V), i.e., a steep decrease and saturation in Ea–V curves, can be clearly explained by introducing spatial locality in the deep-trap distribution. Moreover, it is shown that the anomaly in Ea–V curves occurs synchronously with an anomaly of current; i.e., a steep increase and saturation in I–V curves. Simulated electron-hole distributions clarify the physical mechanism of these anomalies; that is, when applied reverse bias is low and the spatially localized deep traps are outside of the depletion layer, Ea is near Eg because of electrical nonactivity of deep traps. And when applied reverse bias is high and the deep traps are spatially included in the depletion layer, carriers generated from deep-trap centers dominate the carrier transport and Ea is around the energy level (Et) of deep traps located near the midgap. The steep decrease in Ea is thus a result from mixing of the two energy levels (Eg and midgap). Further, it is found that deep-trap-assisted tunneling under a high-field condition reduces Ea. The activation energy defined by the slope in the (log I) versus (1/T) plots is therefore not considered a direct indicator of real Et. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 86 (1999), S. 1443-1448 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A two-dimensional model of a strained Si/Si1−xGex transistor with δ-doped layers was developed. A semiclassical drift diffusion model is used to study the effects of different conduction-band offsets and variation of the distance between the Si channel and an n-type δ-doped layer as well as the thickness of this δ-doped layer at room temperature. We found that a large conduction-band offset, or a large Ge concentration, confines electrons more strongly to the Si channel. These factors raise the drain current when the doping level per unit area is constant. The area between the Si channel and the δ-doped layer and the δ-doped layer itself forms a barrier to electrons donated by the donor atoms in the δ-doped layer. Hence, the smaller the distance between the Si channel and the δ-doped layer and the thinner the δ-doped layer, the larger the number of electrons in the Si channel. Through the present analysis, an optimum design concept is clarified for device applications of Si/Si1−xGex systems. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 60 (1992), S. 1492-1494 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new concept in one-dimensional electron-gas (1DEG) systems is proposed by introducing periodic bending of the heterointerface of an n-AlGaAs/u-GaAs modulation-doped structure. The carrier densities and the electrostatic potential of this system are numerically analyzed based on the classical drift-diffusion model where the doping concentration ND of n-AlzG1−zAs is 1.0×1018 cm−3, the aluminum molar fraction z of AlzGa1−zAs is 0.3, the carrier density of p-type GaAs is 1.0×1014 cm−3, and the bending angle of the heterointerface is 90°. We found that electrons are more accumulated in convex regions of the u-GaAs layer than in concave ones, and the electron density in a convex region is about twice that in the conventional two-dimensional electron-gas structure. We can treat this high density of electrons as a 1DEG channel for field-electron transistors (FETs) when the period of the bending interface is about 850 A(ring).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: NGFI-B and RNR-1 are closely related transcription factors that constitute a distinct subclass within the steroid/thyroid hormone receptor superfamily. They have been implicated in neuronal differentiation, neuroendocrine regulation of adrenocortical function and T-cell apoptosis. In this study, we measured and compared NGFI-B and RNR-1 mRNA levels in various adult rat tissues and in the developing rat brain by means of the quantitative reverse transcription-polymerase chain reaction. The use of RNA standards synthesized in vitro allowed direct comparison of the amount of the transcripts of these two genes. We demonstrated that the transcripts of both genes were present in all tissues examined although the expression levels widely varied. We found the highest constitutive expression of both genes in the pituitary. High levels of NGFI-B were also expressed in the cerebral cortex, muscle, ventral prostate, thymus and adrenal glands, whereas high levels of RNR-1 expression were restricted to the pituitary and cerebral cortex. These findings were consistent with the notion that NGFI-B and RNR-1 are involved in various signal transduction systems in diverse cell types. The amount of NGFI-B mRNA was greater than that of RNR-1 mRNA in all adult rat tissues, with the highest ratio of NGFI-B relative to RNR-1 expression in the muscle and leukocytes. In contrast, fetal rat brain showed relatively high RNR-1 gene expression. These findings suggested that the NGFI-B and RNR-1 genes are differentially expressed in a tissue-specific and developmentally regulated manner.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1432-2307
    Keywords: Thyroid medullary carcinoma ; C-cell ; Gastrin releasing peptide ; Calcitonin ; Immunostaining
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty medullary carcinomas of the thyroid (MCT) with documented calcitonin (CT) production were studied immunohistochemically for the production of gastrin releasing peptide (GRP), a mammalian counterpart of amphibian bombesin. GRP-positive cells, revealed by an unlabelled peroxidase-antiperoxidase immunoenzyme histochemistry were found in 81% (34/40) of the MCTs. Variable numbers of tumor cells in positive MCTs were immunostained for GRP. In 3 cases with Sipple's syndrome, cells in scattered microscopic MCT nodules and hyperplastic intrafollicular C cells of the thyroid were frequently positive for GRP as well as for CT. Non-neoplastic C cells (or CT-positive cells) of the human thyroids were also positive for GRP. In the neoplastic and non-neoplastic C cell system, some cells were confirmed to be immunoreactive with both anti-GRP and anti-CT. All these findings indicate that GRP and CT are closely associated peptide hormones produced by the C cell system.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    ISSN: 1432-2307
    Keywords: Endocrine pancreatic tumours ; WDHA syndrome ; Peptide hormones ; Immunostaining
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nine pancreatic endocrine tumours of patients with watery diarrhoea hypokalaemia achlorhydria (WDHA) syndrome were examined by immunohistochemistry and electron microscopy. All cases revealed neoplastic proliferation of VIP (vasoactive intestinal peptide)-immunoreactive (IR) cells. Immunoreactivity to a novel peptide hormone PHM-27, which is processed from a common big precursor peptide of VIP (prepro VIP/PHM-27), was identified in VIP-IR cells of 8 tumours. VIP-PHM-IR cells had secretory granules measuring about 130 to 220 nm in diameter. Radioimmunoassay of tumour tissue extracts showed high VIP and PHM contents in proportional amounts in most cases. According to the results of immunostaining, the 8 tumours fell into two large groups; 5 with PP (pancreatic polypeptide)-IR cells and 3 with CT (calcitonin)-IR cells. The former group demonstrated VIP cells and PP cells intermingled in various proportions, including one tumour in which coexistence of PP-IR and VIP-IR in the same cells was demonstrated. Cell heterogeneity of the tumours and possible relationships of VIP, PP and CT cells were discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Compared to hereditary medullary thyroid carcinoma (MTC), sporadic MTC tends to be unicentric and confined to one lobe. Patients with sporadic MTC usually undergo total thyroidectomy because of a possible hereditary or bilateral process. We evaluated the usefulness of germline RET oncogene mutation analysis in surgery for apparently sporadic MTC and performed unilateral surgery on patients without detectable mutation. In 36 patients with a preoperative diagnosis of apparently sporadic MTC, we performed germline RET oncogene mutation analyses: before surgery in 8 recent patients and after surgery in 28 who had been treated before 1996. Of the latter, 5 had bilateral MTC. DNA samples were extracted from their peripheral blood, and the polymerase chain reaction products of the RET proto-oncogene were analyzed using single-strand conformation polymorphism analysis and the direct sequencing methods. Before 1996 we often performed total thyroidectomy but changed to hemithyroidectomy thereafter, except in one patient with associated Graves' ophthalmopathy. Our minimal standard practice included systematic central and ipsilateral neck dissection. The outcome was assessed in terms of gastrin- and calcium-stimulated plasma calcitonin levels. Germline RET mutations were found in six patients. Five of these patients had bilateral MTC, whereas all 30 patients without mutation had unilateral disease. Hemithyroidectomy in seven of our recent patients resulted in normalization of plasma calcitonin levels in all, although four were found to have microscopic lymph node involvement. In conclusion, hemithyroidectomy with systematic central and ipsilateral neck dissection is an appropriate procedure for patients with sporadic MTC without detectable germline RET mutations.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...