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  • 1
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 69 (1991), S. 384-389 
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: We investigated the intragranular critical current density Jc in YBa2Cu4O8 prepared by two routes with different oxygen pressures at various temperatures and applied fields. A relationship between the Jc's and the microstructures observed by transmission electron microscopy is discussed. The magnitude of Jc for the low oxygen processed sample is higher by a factor of 5 than that for the high oxygen pressure sample. Transmission electron microscopy reveals that the sample prepared at high oxygen pressure shows an almost perfect stacking sequence, but the low oxygen pressure prepared one has a severely distorted structure. We conclude that the difference in Jc(H) for the samples must be related to the different microstructures. Jc at a fixed magnetic field shows an exponential temperature dependence similar to that seen in other high-Tc superconductors. The field dependence is Jc∝H−n with n between 0.5 and 1.5, and with the n value becoming larger at higher temperatures. This type of the behavior may arise from the two-dimensional character of YBa2Cu4O8.
    Materialart: Digitale Medien
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 9 (1986), S. 0 
    ISSN: 1460-2695
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Maschinenbau
    Notizen: Ordinary short-term creep fatigue tests were carried out on a servo-hydraulic testing machine for various heat resistant steels. From these results a life prediction method in the long-term creep-fatigue regime is proposed using creep rupture ductility data up to 105 h. To verify the predicted life the authors have developed a new type of testing machine driven by thermo-actuator which can evaluate the long-term creep-fatigue behaviour of materials beyond 104 h.
    Materialart: Digitale Medien
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  • 3
    ISSN: 1436-2813
    Schlagwort(e): benign biliary stricture ; biliobiliary anastomosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The inverting and everting methods of biliobiliary anastomoses were compared histopathologically and electron microscopically. Epithelialization started on the 3rd post-operative day and occurred within 8 mm of the anastomosis with an earlier and more active epithelialization being seen in the proximal area than in the distal. A rapid decrease of the mucosal defect was seen for 3–5 days which slowed down thereafter, and closure was achieved by 30 days after the anastomosis in both groups. The everted group showed a smoother and more rapid healing process, quicker epithelialization, and less mucosal defects than the inverted group. In the chronic phase, the inverted group showed more papillary hyperplasia and more pronounced fibrosis of the wall. The stricture index, being the internal circumference of the common bile duct: proximal×2/anastomosis site + duodenal×100, of the everted group was 123.7% compared to 146.7% for the inverted group, but there was no statistical difference. There was no difference in the total area of crypts, representing the epithelialization, between the two groups. Anastomoses with proximal dilatation therefore healed more slowly than those without dilatation. These findings show everted anastomosis to be superior to inverted anastomosis and thus support the usefulness of T-tube drainage to prevent post-operative dilatation of the bile duct.
    Materialart: Digitale Medien
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  • 4
    ISSN: 1436-2813
    Schlagwort(e): α2β1 integrin ; α3β1 integrin ; metastasis ; gastric carcinoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The expression of α2β1 and α3β1 integrins was studied immunohistochemically in 110 resected human gastric carcinomas. Formalin-fixed and paraffin-embedded samples were serially sectioned and stained with monoclonal antibodies specifically against the α2 and α3 subunits of β1 integrins. Approximately 27% of the tumors expressed α3β1 integrin, and 20% expressed α3β1 integrin. The expression of α3β1 integrin was associated with lymph node and liver metastases (P〈0.05 andP〈0.05, respectively), and the expression of α3β1 integrin was associated with liver and peritoneal metastases (P〈0.005 andP〈0.0005, respectively). A multivariate analysis by the logistic regression model revealed that the expression of α3β1 and/or α3β1 integrins was an independent factor related to liver metastasis, and that the expression of α3β1 integrin was as strong an influence on the formation of peritoneal metastases as the depth of invasion. The expression of α3β1 integrin also correlated with increased invasiveness of the tumor; however, there was no correlation between α2β1 integrin expression and the invasiveness. These results suggest that α2β1 and α3β1 integrins have separate influences on the metastatic properties of cancer cells.
    Materialart: Digitale Medien
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  • 5
    ISSN: 1436-2813
    Schlagwort(e): Key Words:α2β1 integrin ; α3β1 integrin ; metastasis ; gastric carcinoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: 2 β1 and α3β1 integrins was studied immunohistochemically in 110 resected human gastric carcinomas. Formalin-fixed and paraffin-embedded samples were serially sectioned and stained with monoclonal antibodies specifically against the α2 and α3 subunits of β1 integrins. Approximately 27% of the tumors expressed α2β1 integrin, and 20% expressed α3β1 integrin. The expression of α2β1 integrin was associated with lymph node and liver metastases (P 〈 0.05 and P 〈 0.05, respectively), and the expression of α3β1 integrin was associated with liver and peritoneal metastases (P 〈 0.005 and P 〈 0.0005, respectively). A multivariate analysis by the logistic regression model revealed that the expression of α2β1 and/or α3β1 integrins was an independent factor related to liver metastasis, and that the expression of α3β1 integrin was as strong an influence on the formation of peritoneal metastases as the depth of invasion. The expression of α3β1 integrin also correlated with increased invasiveness of the tumor; however, there was no correlation between α2β1 integrin expression and the invasiveness. These results suggest that α2β1 and α3β1 integrins have separate influences on the metastatic properties of cancer cells.
    Materialart: Digitale Medien
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  • 6
    ISSN: 1436-0691
    Schlagwort(e): sclerosing cholangiocarcinoma ; primary sclerosing cholangitis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Two patients with a sclerosing type of cholangiocarcinoma are reported. One, a 68-year-old male, presented with jaundice and mild right upper abdominal pain. Endoscopic retrograde cholangiography showed diffuse narrowing and irregularity of the intra- and extrahepatic bile ducts, suggestive of primary sclerosing cholangitis. The other patient was a 72-year-old female who complained of slight right upper abdominal pain, lassitude, and anorexia. Both ultrasonography and computed axial tomography demonstrated slight dilatation of the anterior branch of the right hepatic duct, but no mass. Endoscopic cholangiography revealed stenosis of that duct and diffuse irregularity of the other intrahepatic ducts, also suggestive of primary sclerosing cholangitis. In both patients, however, transpapillary cytology of bile demonstrated malignant cells, and biopsy from within the bile duct showed cholangiocarcinoma. Both transpapillary cytology and biopsy, especially the latter, are useful procedures for the diagnosis of this unique clinical entity.
    Materialart: Digitale Medien
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  • 7
    ISSN: 1436-2813
    Schlagwort(e): localized peritonitis ; obstructive colitis ; rectal carcinoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A case of obstructive colitis associated with rectal carcinoma in a 56 year old Japanese man is reported herein. He presented to Shinkokura Hospital with severe abdominal pain following a one month history of anal bleeding and mild abdominal pain. On palpation, muscle guarding was observed in the left lower quadrant and the white blood cell count was 14,200/mm3. An exploratory laparotomy was performed under the provisional diagnosis of acute abdomen, which revealed localized peritonitis 8 cm oral to an area of rectal carcinoma. An anterior resection of the lesion was therefore performed together with a descendo-proctostomy. The histopathologic diagnosis revealed adenocarcinoma and obstructive colitis involving the entire thickness of the sigmoid colon and resultant fibrino-purulent peritonitis. His postoperative course was uneventful and he was continuing to do well on the 30th postoperative day, at the time of writing. The clinical significance of this combination of obstructive colitis with rectal carcinoma is briefly discussed following the presentation of this case.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Surgery today 22 (1992), S. 305-312 
    ISSN: 1436-2813
    Schlagwort(e): endocrine tumor of the pancreas ; immunohistochemistry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A total of 24 patients with endocrine neoplasms of the pancreas were clinicopathologically and immunohistochemically studied. They consisted of 18 patients with adenoma and 6 with carcinoma. Of the 24 patients, 13 developed attacks of hypoglycemia due to hyperinsulinemia, and 1 developed an uncontrollable duodenal ulcer caused by the hypersecretion of gastrin, however, the remaining 10 were asymptomatic. No prediction could be made as to the site of origin of the tumors. A clear difference was seen between adenoma and carcinoma in the size of the mass, the mean greatest diameter of the 18 adenoma cases being 1.7 cm, while that of the 6 carcinoma cases was 7.3cm. One of the 13 insulinomas and a gastrinoma was malignant, while all 24 tumors were positive for neuron-specific enolase. The 13 insulinomas were diffusely positive for insulin and 5 were also shown to be focally immunoreactive for gastrin, with 3 also being immunoreactive for somatostatin and 2 for pancreatic polypeptide. The gastrinoma showed immunoreactivity for somatostatin, insulin, pancreatic polypeptide, and glucagon in addition to a positivity to gastrin. The above findings thus indicate the multiple hormone synthesis of endocrine neoplasms of the pancreas.
    Materialart: Digitale Medien
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Surgery today 19 (1989), S. 381-386 
    ISSN: 1436-2813
    Schlagwort(e): hamartoma ; spleen
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A 39-year-old Japanese man with a splenic hamartoma who underwent surgery, is reported herein. The patient had a volvulus of the transverse colon and acute Type A hepatitis. His symptoms included fever, abdominal pain and icterus and the serum chemistry showed liver dysfunction and an elevation of hepatitis A antibody levels. Barium enema revealed a volvulus of the transverse colon. Ultrasonogram showed a hypoechoic mass and angiogram showed evidence of stretching of the intrasplenic vessels in the arterial phase and a hypovascular mass lesion in the venous phase. Macroscopically, the tumor was a well-defined, whitishyellow, hard nodule. Microscopically, the tumor was composed of fibrous scar tissue containing scattered red pulp tissues and the histologic diagnosis was a splenic hamartoma of the fibrous type. The patient’s postoperative recovery was uneventful. The clinical features of splenic hamartoma are reviewed in this report and the differential diagnosis is also discussed.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Surgery today 27 (1997), S. 238-242 
    ISSN: 1436-2813
    Schlagwort(e): adenoid cystic carcinoma ; esophageal carcinoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The case of a 70-year-old Japanese woman with adenoid cystic carcinoma (ACC) of the esophagus is presented herein. The patient presented with progressive dysphagia, and an upper gastrointestinal series and esophagogastroscopy revealed a protruding tumor located in the middle portion of the esophagus. Ultrasonography (US) and computed tomography (CT) suggested a lymph node metastasis between the left lobe of the liver and the esophagocardiac junction. Histopathologic examination of a biopsy specimen showed squamous cell carcinoma (SCC) and a subtotal esophagectomy was performed under the preoperative diagnosis of esophageal carcinoma. However, the histopathologic diagnosis of the resected specimen proved to be ACC of the esophagus with a lymph node metastasis around the left gastric artery. We report the clinicopathological findings of this case and briefly discuss the clinical implications of ACC.
    Materialart: Digitale Medien
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