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  • 1
    Electronic Resource
    Electronic Resource
    Critical current density and microstructure of YBa2Cu4O8 (1991)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 69 (1991), S. 384-389 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We investigated the intragranular critical current density Jc in YBa2Cu4O8 prepared by two routes with different oxygen pressures at various temperatures and applied fields. A relationship between the Jc's and the microstructures observed by transmission electron microscopy is discussed. The magnitude of Jc for the low oxygen processed sample is higher by a factor of 5 than that for the high oxygen pressure sample. Transmission electron microscopy reveals that the sample prepared at high oxygen pressure shows an almost perfect stacking sequence, but the low oxygen pressure prepared one has a severely distorted structure. We conclude that the difference in Jc(H) for the samples must be related to the different microstructures. Jc at a fixed magnetic field shows an exponential temperature dependence similar to that seen in other high-Tc superconductors. The field dependence is Jc∝H−n with n between 0.5 and 1.5, and with the n value becoming larger at higher temperatures. This type of the behavior may arise from the two-dimensional character of YBa2Cu4O8.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.347726
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  • 2
    Electronic Resource
    Electronic Resource
    PREDICTION AND EVALUATION OF LONG-TERM CREEP-FATIGUE LIFE (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 9 (1986), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Ordinary short-term creep fatigue tests were carried out on a servo-hydraulic testing machine for various heat resistant steels. From these results a life prediction method in the long-term creep-fatigue regime is proposed using creep rupture ductility data up to 105 h. To verify the predicted life the authors have developed a new type of testing machine driven by thermo-actuator which can evaluate the long-term creep-fatigue behaviour of materials beyond 104 h.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1986.tb00438.x
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  • 3
    Electronic Resource
    Electronic Resource
    Cancer of the extrahepatic bile duct: A clinicopathologic study of immunohistochemistry for CEA, CA19-9, and p21 (1988)
    Springer
    World journal of surgery 12 (1988), S. 11-17 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Parmi 422 malades présentant un cancer de l'aire bilio-duodénopancréatique 86 étaient porteurs d'un cancer des voies biliaires extra-hépatiques, les cancers de l'ampoule, et les cancers du segment duodénal du cholédoque étant exclus. Les paramètres pronostiques significatifs furent les suivants: le type histologique, la présence de métastases ganglionnaires, l'extension périneurale, et la mise eh évidence immunohistologique de CEA. La présence dés marqueurs CEA, CA19-9, et p21 a été découverte respectivement dans 75, 58, et 20 des 82 cas. Quatre de ces cancers furent considérés comme précoces car la tumeur polypoide était confinée à la paroi du canal bilaire. Ils sont en vie après une période post-opératoire s'étendant de 1 1/2 ans à 7 1/2 ans.
    Abstract: Resumen Un total de 86 pacientes con cáncer de los canales biliares extrahepáticos (excluyendo canales biliares intraduodenales y la ampolla de Vater) fueron estudiados en sus aspectos clinicopatológicos, habiendo sido seleccionados entre 422 pacientes con cáncer de la región biliopancreatoduodenal. Parámétros significativos que influencian el pronóstico incluyeh el grado histológico de diferenciación, las metástasis ganglionares, la invasión perineural, y la demostración inmunohistoquímica de antígeno carcinoembriónico. Las células tumorales mostraron reactancia a ACE, CA19-9, y p21 en 75, 58, y 20, respectivamente, de los 82 casos de cáncer de los canales biliares. Cuatro tumores en esta serie fueron clasificados como cánceres tempranos de los canales biliares, exhibiendo una masa polipoide dentro de las paredes canaliculares. Los pacientes con carcinoma temprano están vivos y su evolución postoperatoria osciló entre 1 año 6 meses y 7 años 6 meses.
    Notes: Abstract A total of 86 patients with extrahepatic bile duct cancer (excluding intraduodenal bile ducts and the ampulla of Vater) selected from 422 patients with cancer of the biliopancreatoduodenal region were studied clinicopathologically. Significant parameters influencing the prognosis include histologic grade of differentiation, lymph node metastasis, perineural invasion, and immunohistochemical demonstration of carcinoembryonic antigen (CEA). Tumor cells had CEA, carbohydrate antigen 19-9 (CA19-9),and c-Ha-ras p21 antigen (p21) reactants in 75, 58, and 20 patients, respectively, of the 82 patients with bile duct cancer. Four tumors were classified as early bile duct cancers, showing a polypoid mass restricted within the bile duct wall. The patients with such early carcinoma were alive with the postoperative course ranging from 1 1/2 to 7 1/2 years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01658480
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  • 4
    Electronic Resource
    Electronic Resource
    Manometric Evidence of Improved Early Gastric Stasis by Erythromycin after Pylorus-preserving Pancreatoduodenectomy (2000)
    Springer
    World journal of surgery 24 (2000), S. 1236-1242 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Gastric stasis is a frequent complication of pylorus-preserving pancreatoduodenectomy (PPPD). We demonstrated that it might be attributable to delayed recovery of phase III activity of the gastric migrating motor complex due to low concentrations of plasma motilin caused by resection of the duodenum. Leucine 13-motilin is effective for treating gastric stasis, but it is not yet available for clinical use. Whether erythromycin would improve early gastric stasis after PPPD was tested clinically and by manometry. A manometric tube assembly and a gastrostomy tube were inserted in the stomach of 10 patients at PPPD for pressure recording from the gastric antrum and jejunum and for gastric juice drainage, respectively. After baseline recording, erythromycin 5 mg/kg was given intravenously on day 14 and saline as a placebo on day 17 every 4 hours four times a day. The daily volume of gastric juice output and the gastric motility index were measured. The mean period until the return of gastric phase III was 31 ± 1 days. Erythromycin significantly increased the gastric motility index from 7.9 ± 1.3 mmHg to 15.7 ± 1.8 mmHg (p= 0.0005), whereas saline did not (7.2 ± 1.6 mmHg to 6.5 ± 1.2 mmHg; p= 0.21). Erythromycin significantly decreased the gastric juice output from 1080 ± 190 ml to 738 ± 199 ml (p 〈 0.0001), but the saline injections did not (1064 ± 174 ml to 1115 ± 189 ml; p= 0.35). Erythromycin, a universally available motilin agonist, is a safe, effective, potent drug for the treatment of early gastric stasis after PPPD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002680010244
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  • 5
    Electronic Resource
    Electronic Resource
    Clinicopathologic Differences between Long-Term and Short-Term Postoperative Survivors with Advanced Gallbladder Carcinoma (1997)
    Springer
    World journal of surgery 21 (1997), S. 98-102 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The objective of this study was to determine histopathologic factors that influence the failure or success of extended cholecystectomy and more aggressive surgery to attain long-term survival in patients with advanced carcinoma of the gallbladder. Of 46 patients with carcinoma of the gallbladder who had undergone surgical resection, 36 had advanced carcinoma invading to or beyond the subserosal layer. Among these 36 patients were 10 long-term survivors (〉 5 years) and 11 short-term survivors who died of recurrence (〈 37 months) after extended cholecystectomy or more extensive surgery. Factors were compared between the two groups. Significant factors observed in the long-term survivors were the depth of invasion limited to the subserosal layer ( p 〈 0.05), hepatic infiltration 〈 5 mm ( p 〈 0.01), histologic grade of papillary or well differentiated adenocarcinoma ( p 〈 0.01), absent or minimal venous, lymphatic, and perineural invasion ( p 〈 0.01), and lymph node metastasis limited to the hepatoduodenal ligament ( p 〈 0.05). It was concluded that the patients with subserosal invasion have a hope for long-term survival by extended cholecystectomy or more aggressive surgery when hepatic infiltration and venous, lymphatic, and perineural invasion are absent or minimal, the histologic grade is papillary or well differentiated adenocarcinoma, and lymph node metastasis is limited to the hepatoduodenal ligament.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002689900200
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  • 6
    Electronic Resource
    Electronic Resource
    Role of Surgery for Gallbladder Carcinoma with Special Reference to Lymph Node Metastasis and Stage Using Western and Japanese Classification Systems (2000)
    Springer
    World journal of surgery 24 (2000), S. 1271-1277 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The role of radical resection in the treatment of gallbladder carcinoma was examined with special reference to lymph node metastasis using two classifications: one proposed by the American Joint Committee on Cancer (AJCC) and the other by the Japanese Society of Biliary Surgery (JSBS). Histologic evaluations for the depth of tumor invasion (T), lymph node metastasis (N), stage, and follow-up for a mean period of 38 months (range 4–185 months) were completed in 52 patients with gallbladder carcinoma who underwent surgical resection from 1982 to 1997. The definition of T was similar in the two classifications. The extent of nodal involvement (N, AJCC; n, JSBS), stage, and survival were examined. In the absence of lymph node metastasis, the 5-year survival rate reached 71%. The 5-year survival rate in patients with involved nodes confined to the hepatoduodenal ligament, posterosuperior pancreaticoduodenal region, or along the common hepatic artery (N1 and part of N2 by AJCC; n1 and n2 by JSBS) approximated 28%. In contrast, postoperative survival was poor in the presence of more extensive nodal involvement (rest of N2 by AJCC; n3 and n4 by JSBS), with no 2-year survivors. The definition of stage I was the same in both classifications, and all patients in this stage are alive. The 5-year survival rates in stages II and III by the AJCC were 70.7% and 22.4%, respectively, and those by JSBS 61.9% and 23.1%, respectively. Thus the survival rates in stages I to III were essentially similar irrespective of the staging system. Stage IV showed significantly worse survival than stage III by the JSBS classification. In contrast, the differentiation of stage IV from III by the AJCC was not significant because of the better survival in stage IV that contained any T with nodal involvement in the posterosuperior pancreaticoduodenal region and along the common hepatic artery. Radical resection should be considered for patients with stage I to III disease defined by either classification and applied to the tumor invasion up to T3 with nodal involvement confined to the hepatoduodenal ligament, posterosuperior pancreaticoduodenal region, and along the common hepatic artery. The role of radical surgery seems to be limited in patients with more extensive tumor invasion or lymph node metastasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002680010253
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  • 7
    Electronic Resource
    Electronic Resource
    Development of an ulcer in the side-to-side ansatomosis of a jejunal pouch after proximal gastrectomy reconstructed by jejunal interposition: Report of a case (1998)
    Springer
    Surgery today 28 (1998), S. 1270-1273 
    Details
    ISSN: 1436-2813
    Keywords: jejunal ulcer ; jejunal interposition ; gastric cancer ; pouchitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present herein the first reported case of a deep ulceration developing in the pouch of a jejunal side-to-side anastomosis following the interposition of a jejunal U-shaped pouch (jejunal pouch), performed as reconstruction. A 47-year-old woman underwent a proximal gastrectomy and interposition of a jejunal pouch for early gastric cancer, 4 mouths after which she began to develop a fever. Esophagogastroscopy revealed a deep ulceration in the side-to-side anastomosis of the jejunal pouch. Her serum gastrin level was much higher than the normal range, and 24-h monitoring of the intraremnant stomach pH revealed that it was below 7.0 at night. A peptic ulcer was thought to be one of the causes of the pouchitis. Due to the drug-resistant ulceration and fever, a reoperation was performed, in which the jejunal pouch and remnant stomach were removed and Roux-en-Y reconstruction was done. There were no postoperative complications, and the fever resolved after surgery. Reconstruction of the jejunal pouch after proximal gastrectomy is recommended from the standpoint of quality of life (QOL); however, further studies on the size of the remnant stomach and the length of the interposed jejunal pouch are necessary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02482813
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  • 8
    Electronic Resource
    Electronic Resource
    Establishment and characterization of human pancreatic carcinoma lines with a high metastatic potential in the liver of nude mice (1999)
    Springer
    Surgery today 29 (1999), S. 519-525 
    Details
    ISSN: 1436-2813
    Keywords: liver metastasis ; human pancreatic carcinoma ; nude mice ; motility ; adhesion molecule
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate of human pancreatic cancer metastasis to the liver, a pancreatic carcinoma line, HPC-3, was injected into the spleens of nude mice. The cells from a few liver metastatic foci of the mice injected with HPC-3 were expanded in vitro and subsequently injected into the spleens of nude mice. By repeating these procedures, we were able to obtain a cell line, designated HPC-3H4. The mice were observed to have liver metastasis in 6 of 6 (100%) cases injected with HPC-3H4, whereas the rate was 0% at 3 weeks after the intrasplenic injection of HPC-3. The tumorigenicity of HPC-3H4 was more rapid than that of HPC-3. The motile activity of HPC-3H4 was also stronger than that of HPC-3, and the adhesion to the extracellular matrix of HPC-3H4 was stronger than that of HPC-3. We also analyzed the cell surface expression of the metastasis-related adhesion molecules. As a result, no substantial changes were observed in the expression level of adhesion molecules. These results suggest that HPC-3H4 is useful for studies aimed at the prevention of liver metastasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02482346
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  • 9
    Electronic Resource
    Electronic Resource
    Adenoid cystic carcinoma of the esophagus: Report of a case (1997)
    Springer
    Surgery today 27 (1997), S. 238-242 
    Details
    ISSN: 1436-2813
    Keywords: adenoid cystic carcinoma ; esophageal carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The case of a 70-year-old Japanese woman with adenoid cystic carcinoma (ACC) of the esophagus is presented herein. The patient presented with progressive dysphagia, and an upper gastrointestinal series and esophagogastroscopy revealed a protruding tumor located in the middle portion of the esophagus. Ultrasonography (US) and computed tomography (CT) suggested a lymph node metastasis between the left lobe of the liver and the esophagocardiac junction. Histopathologic examination of a biopsy specimen showed squamous cell carcinoma (SCC) and a subtotal esophagectomy was performed under the preoperative diagnosis of esophageal carcinoma. However, the histopathologic diagnosis of the resected specimen proved to be ACC of the esophagus with a lymph node metastasis around the left gastric artery. We report the clinicopathological findings of this case and briefly discuss the clinical implications of ACC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00941652
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  • 10
    Electronic Resource
    Electronic Resource
    Development of an Ulcer in the Side-to-side Anastomosis of a Jejunal Pouch After Proximal Gastrectomy Reconstructed by Jejunal Interposition: Report of a Case (1998)
    Springer
    Surgery today 28 (1998), S. 1270-1273 
    Details
    ISSN: 1436-2813
    Keywords: Key Words: jejunal ulcer ; jejunal interposition ; gastric cancer ; pouchitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005950050331
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