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  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Makromolekulare Chemie 207 (1993), S. 101-109 
    ISSN: 0003-3146
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Urease wurde in Hydrogelen immobilisiert, die durch Bestrahlen ternärer Mischungen von N-Vinyl-2-pyrrolidon/Wasser/Vernetzer mit y-Strahlen hergestellt wurden. Als Vernetzer wurden Ethylenglycoldimethacrylat und Trimethylolpropan-triacrylat verwendet, wobei Hydrogele mit Unterschieden in Quellungsvermögen und Netzwerkdichte erhalten wurden. Die Aktivität der immobilisierten Urease wurde zeitlich im optimalen Temperatur- und pH-Bereich verfolgt. Während bei Hydrogelen mit einem mittleren Molekulargewicht zwischen den Netzpunkten Mc 〉 2000 die Urease ausgewaschen wird, sind solche mit Mc 〈 2000 über einen längeren Zeitraum aktiv.
    Notes: Urease enzyme was immobilized in hydrogels prepared from vinyl pyrrolidone/water/crosslinking agent ternary mixtures by γ-irradiation of the solutions at room temperature. Two types of crosslinking agents used, namely ethylene glycol dimethacrylate and trimethylol propane triacrylate, yielded hydrogels with different swelling and crosslink density properties. The activity of immobilized urease was measured at the optimum conditions of temperature and pH over a period of time. It has been determined that for hydrogels with average molecular weights between crosslinks, Mc, above 2000, urease leakage is a serious problem. When Mc is around and below this value, immobilized systems showed a long time activity.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 30 (1992), S. 2055-2057 
    ISSN: 0887-624X
    Keywords: end group effect ; end-to-end linking ; radiation crosslinking ; poly(ethylene glycol) ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 36 (1998), S. 213-219 
    ISSN: 0887-6266
    Keywords: solubility parameter ; hydrogels ; poly(n-vinyl 2-pyrrolidone) ; swelling ; Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The solubility parameters of pure Poly(n-vinyl 2-pyrrolidone) (PVP) and Poly(n-vinyl 2-pyrrolidone/ethylene glycol dimethacrylate)P(VP/EGDMA) hydrogels have been evaluated via swelling experiments. Twenty solvents with various solubility parameters have been used in the swelling experiments. Considering the limitations of using the approach as developed by Gee, we have applied an asymmetric double sigmodial equation for locating the peak maxima in swelling curves. The solubility parameters are evaluated via this new approach. The solubility parameter of pure PVP is determined to be 11.38 ± 0.11 Hb. The incorporation of EGDMA into the gel system slightly reduced the solubility parameter. The influence of relative amount of EGDMA on the solubility parameter was investigated, and evaluated values compared with literature and theoretically determined solubility values by group contribution values of van Krevelen, Small, and Hoy. © 1998 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 36: 213-219, 1998
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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