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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 235 (1988), S. 308-313 
    ISSN: 1432-1459
    Keywords: Circadian rhythm ; VEP ; Body temperature ; Psychomotor performance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Amplitudes and latencies of components of visual evoked potentials (VEPs) were analysed during the 24-h cycle in humans. Circadian variations of other physiological parameters (oral temperature, urine volume and urinary potassium excretion) and of psychomotor performance (grip strength, tapping rate, visual reaction time and performance on a letter cancellation test) were also assessed. Eight male volunteers (aged 20–34 years) were tested twice over a period of 30 h. Test sessions took place every 3 h (1100 hours, 1400 hours etc.). VEPs were elicited by checkerboard pattern reversals. Significant circadian variations in the VEPs were found for the latencies of the P100 and N140 components, which were longest between 2 a.m. and 5 a.m. (P100: 103 ms; N140: 138 ms) and shortest at about 5 p.m. (P100: 97 ms; N140: 130 ms). Pronounced circadian variations were also observed in physiological parameters and in psychomotor performance measures. Circadian variation of oral temperature was correlated with the 24-h profiles of most of the other variables. Time courses of VEP latencies and oral temperature were moderately negatively correlated. However, from the data presented it seems premature to conclude that there is a common pacemaker for the circadian variations of the different parameters investigated.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 46 (1990), S. 870-871 
    ISSN: 1420-9071
    Keywords: Circadian rhythms ; activity ; wakefulness ; humans ; homeostatic control ; isolation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Locomotor activity was recorded in 14 subjects who lived singly in an isolation unit for 16 to 88 days. Their free-running circadian rhythms had a mean period of 25.9 h, with individual means in the duration of wakefulness (α) ranging from 12.1 to 22.9 h. Intraindividually, the hourly means of activity were negatively correlated with α to such a degree that the total amount of activity per ‘day’ remained constant irrespective of large variations in α.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 9 (1953), S. 395-396 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 21 (1970), S. 331-333 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 58 (1980), S. 323-335 
    ISSN: 1432-1440
    Keywords: Circadian rhythms ; Circadian pattern ; Reproducibility ; Circadiane Rhythmen ; Muster der Tagesgänge ; Reproduzierbarkeit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An Hand eigener experimenteller Daten und nach Angaben in der Literatur wird die Reproduzierbarkeit tagesperiodisch variierender Funktionen — des ‚circadianen Musters‘ — in fünf Sektionen geprüft. Sie betreffen das Problem der intraund interindividuellen Variabilität, dargestellt am Gang der Kerntemperatur, die Abhängigkeit des Musters von den Versuchsbedingungen, und als weitere Beispiele Tagesgänge im endokrinen System und bei verschiedenen Blutbestandteilen, im Blutdruck und in der psychomotorischen Leistung. Die Übersicht ist als Beitrag gedacht zu der Frage, welche Bedeutung der circadianen Zeitstruktur zukommt für die Bestimmung von Referenzwerten und somit auch für die Diagnostik.
    Notes: Summary On the basis of our own experimental data and those from the literature, the reproducibility of day-night variations in physiological functions — their ‘circadian pattern’ — is examined in five sections. They concern the problem of intra- and interindividual variability, demonstrated by the rhythm of deep body temperature, the dependence of the pattern on experimental conditions, and as further examples circadian rhythms in the endocrine system, in blood constituents, in blood pressure and in psychomotor performance. The survey is considered to contribute to the question of how important the circadian temporal structure may be in the search for reference values and hence in diagnosis.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 56 (1978), S. 425-435 
    ISSN: 1432-1440
    Keywords: Circadian rhythms ; Hormones ; Sleepwake cycle ; Circadiane Rhythmen ; Hormone ; Schlaf-Wach-Rhythmus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Arbeit bringt in vier Teilen eine Übersicht über die Tagesgänge von Cortisol, Wachstumshormon, Prolactin, Testosteron, LH und FSH im Plasma des Menschen. 1) Versuche mit isolierten Versuchspersonen zeigen, daß dem Tagesgang des Cortisols ein endogen-circadianer Rhythmus zugrunde liegt, der unabhängig vom Schlaf-Wach-Rhythmus verlaufen kann. 2) Die von jeweils mehreren Autorengruppen in guter Übereinstimmung ermittelten Tagesgänge erlauben eine Reihung von Hormonen mit starker circadianer Komponente (z.B. Cortisol) zu solchen mit schwächerer (Testosteron) oder fehlender circadianer Komponente (FSH). 3) Der Schlaf-Wach-Rhythmus beeinflußt (mehr oder minder) die Phase der Hormon-Rhythmen; beim Vergleich mehrerer Tagesgänge ist deshalb der Bezug auf die Schlafzeiten dem auf Ortszeit vorzuziehen. 4) Die Tagesgänge von Cortisol und Wachstumshormon des Menschen stimmen befriedigend mit denen anderer Vertebraten-Arten überein.
    Notes: Summary In four sections, the contribution reviews data on 24-hour variations of cortisol, growth hormone, prolactine, testosterone, LH and FSH in the human plasma. 1) Experiments on isolated subjects show that the 24-h variation of cortisol is based on an endogenous circadian rhythm which can be independent from the rhythm of sleep and wakefulness. 2) The various pattern each of which has been described in good correspondence by several groups of authors, suggest a series of hormones with a strong circadian component (e.g. cortisol) to those with a weaker (testosterone) or even without a circadian component (FSH). 3) The sleep-wake-cycle influences the phase of hormone rhythms by various degrees; therefore, a uniform reference to sleep time seems preferable to a reference to local time in order to compare several rhythms. 4) The rhythms of cortisol and growth hormone as described in man agree satisfactorily with those in other vertebrate species.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 44 (1966), S. 790-792 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Basis of Disease 1226 (1994), S. 12-18 
    ISSN: 0925-4439
    Keywords: Alveolar macrophage ; Angiotensin converting enzyme ; Colony-stimulating factor ; Peripheral blood monocyte ; Polymerase chain reaction
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Comparative Biochemistry And Physiology 18 (1966), S. 397-404 
    ISSN: 0010-406X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Comparative Biochemistry And Physiology 16 (1965), S. 507-514 
    ISSN: 0010-406X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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