ISSN:
1435-5604
Keywords:
Polycythemia vera
;
Secondary Hyperparathyroidism
;
Hemodialysis
;
Parathyroid hormone (PTH)
;
Uremic toxin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A case of polycythemia vera complicated by chronic renal failure under maintenance hemodialysis requiring parathyroidectory (PTH) for secondary hyperparathyroidism (2° HPT) is reported. A 62 year old female presented with 75000 white blood cells (WBC)/µl, 703×104 red blood cells (RBC)/µl, 23×104 platelets (PLT)/µl, hyperuricemia and hypertension in 1970 and the diagnosis of polycythemia vera was made. Hemodialysis was started in October 1974 for chronic renal failure. Blood cells in peripheral blood rapidly decreased in number after the beginning of dialysis, reaching the level of 10000∼20000 WBC/µl, and 150∼250×104RBC/µl. In August 1988, marked bone resorption in X-ray picture and high serum alkaline phosphatase and parathyroid hormone (PTH) noted along with 17400 WBC/µl, 370×104RBC/µl and 35.9×104PLT/µl. After subtotal PTX removing 3.21g parathyroid gland, serum PTH rapidly fell. At 3 months after PTX, WBC rose to 23600/µl, RBC 372×104/µl and PLT 94.0×104/µl. At 6 months, WBC was to 31000/µl, RBC 429×104/µl and PLT 78.0×104/µl, suggesting an inhibitory action of PTH on not only RBC, but also WBC and PLT.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02377369
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