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  • 1
    Electronic Resource
    Electronic Resource
    Paediatric Castleman disease: report of seven cases and review of the literature (1999)
    Springer
    European journal of pediatrics 158 (1999), S. 631-637 
    Details
    ISSN: 1432-1076
    Keywords: Key words Castleman disease ; Lymphoproliferative disorder
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Castleman disease is a distinct lymphoproliferative disorder of unknown origin. Seven new cases in children are reported here and 76 cases from the paediatric literature are reviewed. The disease has been reported in 46 females and 37 males, their age ranging from 2 months to 17 years. The disease was localized in 72 cases and multicentric in 11 cases. The hyalinovascular type was more frequently encountered (54%) than the plasma cell type (24%). Laboratory abnormalities were more often associated with the plasma cell type and were mainly represented by anaemia and hypergammaglobulinaemia. Treatment of the localized tumour consisted of surgical excision, whereas treatment of the multicentric form was medical, comprising prednisone and other immunosuppressor drugs. The disease in the paediatric population seems to have a more favourable course than in adults. Conclusion The paediatric features of the disease suggest that Castleman disease in this population could represent an earlier form of the pathology or even suggest a benign lymphoproliferative disorder.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310051166
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Varicella-associated pancytopenia (1990)
    Springer
    European journal of pediatrics 149 (1990), S. 810-811 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01957291
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Nephrotic syndrome and Hodgkin disease in children: a report of five cases (1997)
    Springer
    European journal of pediatrics 156 (1997), S. 239-242 
    Details
    ISSN: 1432-1076
    Keywords: Key words Nephrotic syndrome  ;  Hodgkin disease  ;   Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  This report documents the occurrence of a nephrotic syndrome in five children with Hodgkin disease. In two cases the nephrotic syndrome predated the diagnosis of lymphoma by 6 months and 12 months respectively , while in the other three, the two disorders occurred simultaneously. The nephrotic syndrome resolved in four cases during effective treatment for active Hodgkin disease, while proteinuria remained unchanged in the fifth case with partial control of the lymphoma. The occurrence of a nephrotic syndrome as a manifestation of active Hodgkin disease suggests that some immunological abnormalities play a role in the pathogenesis of the association. Conclusion The possibility of glomerular dysfunction although rare must be considered and actively looked for in all cases of Hodgkin disease. Similarly, any unusual sign or symptom noted in patients with nephrotic syndrome, particularly receiving or having received immunosuppressants, requires thorough investigation to determine the presence or absence of lymphoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050592
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Mastoiditis, meningitis and venous sinus thrombosis caused by Fusobacterium necrophorum (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 339-341 
    Details
    ISSN: 1432-1076
    Keywords: Key words:Fusobacterium necrophorum– Anaerobic meningitis – Mastoiditis – Venous sinus thrombosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The authors report a case of septic venous sinus thrombosis (VST) and meningitis occurring as an early complication of mastoiditis caused by Fusobacterium necrophorum. CT scan was normal, and cerebral angiography was required to diagnose the VST. The evolution was favourable with appropriate antimicrobial therapy and steroids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01956414
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  • 5
    Electronic Resource
    Electronic Resource
    Myelodysplasia in childhood may be a polyclonal disease (1997)
    Springer
    Hematology and cell therapy 38 (1997), S. 325-330 
    Details
    ISSN: 1279-8509
    Keywords: Myelodysplastic syndromes ; Clonality ; Mitochondrial cytopathies ; Malformative syndromes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Myelodysplasia in childhood can be associated with constitutional abnormalities. Two main situations can be observed: constitutional diseases such as Down’s Syndrome may be the first step of a malignant stem cell transformation leading to monoclonal hematopoiesis. However, in other situations such as mitochondrial cytopathies or other polymalformative syndromes, myelodysplasia may simply be the hematological expression of a multi-tissue constitutional disease. In such cases, the bone marrow karyotype is usually found to be normal and, in affected females, clonality studies show a polyclonal pattern. Clonality assessment should be, when possible, a mandatory step before any major therapeutic decision during the course of childhood myelodysplasia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00282-996-0325-0
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    Paper (German National Licenses)
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