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  • 1
    Electronic Resource
    Electronic Resource
    Nephrotic syndrome and Hodgkin disease in children: a report of five cases (1997)
    Springer
    European journal of pediatrics 156 (1997), S. 239-242 
    Details
    ISSN: 1432-1076
    Keywords: Key words Nephrotic syndrome  ;  Hodgkin disease  ;   Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  This report documents the occurrence of a nephrotic syndrome in five children with Hodgkin disease. In two cases the nephrotic syndrome predated the diagnosis of lymphoma by 6 months and 12 months respectively , while in the other three, the two disorders occurred simultaneously. The nephrotic syndrome resolved in four cases during effective treatment for active Hodgkin disease, while proteinuria remained unchanged in the fifth case with partial control of the lymphoma. The occurrence of a nephrotic syndrome as a manifestation of active Hodgkin disease suggests that some immunological abnormalities play a role in the pathogenesis of the association. Conclusion The possibility of glomerular dysfunction although rare must be considered and actively looked for in all cases of Hodgkin disease. Similarly, any unusual sign or symptom noted in patients with nephrotic syndrome, particularly receiving or having received immunosuppressants, requires thorough investigation to determine the presence or absence of lymphoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050592
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  • 2
    Electronic Resource
    Electronic Resource
    Cellular adaptation of the mouse cortical thick ascending limb of Henle's loop (CTAL) to dietary magnesium restriction: enhanced transepithelial Mg2+ and Ca2+ transport (2000)
    Springer
    Pflügers Archiv 439 (2000), S. 765-771 
    Details
    ISSN: 1432-2013
    Keywords: Cortical thick ascending limb Low-Mg2+ diet Mg2+ transport Microperfusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Mice aged 4 or 8 weeks were fed with a low-Mg2+ diet for 1, 2, 3 or 4 days. After 1 day of diet, the urinary excretion of Mg2+ and Ca2+ was strongly reduced in both animal groups (4 and 8 weeks), accompanied by a significant fall in plasma Mg2+ concentration and an increase in urinary volume. This profile persisted after 2, 3 or 4 days of dietary Mg2+ restriction. After 1 day of diet, transepithelial ion net fluxes of Na+, Cl–, Ca2+ and Mg2+ (J Na, J Cl, J Ca, J Mg) measured in vitro from isolated perfused cortical thick ascending limbs (CTALs) of these animals remained unchanged. After 2 days of diet, measurements of J Ca and J Mg in isolated perfused CTALs showed that transepithelial Mg2+ and Ca2+ reabsorption were enhanced in CTALs from Mg2+-depleted, 8-week-old animals, whereas transepithelial Mg2+ and Ca2+ transport were not altered in 4-week-old mice. J Na and J Cl and the transepithelial potential (PDte) were not modified in CTALs from either animal group. Our results suggest that a low-Mg2+ diet leads to urinary retention of Mg2+ and Ca2+ which is most likely due to increased Mg2+ and Ca2+ transport in the CTAL. Furthermore, in response to dietary Mg2+ restriction, the reabsorption of divalent cations in the CTAL of adult, but not of young, mice undergoes cellular adaptation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004249900197
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  • 3
    Electronic Resource
    Electronic Resource
    Cluster of cases of haemolytic uraemic syndrome due to unpasteurised cheese (1996)
    Springer
    Pediatric nephrology 10 (1996), S. 203-205 
    Details
    ISSN: 1432-198X
    Keywords: Key words: Haemolytic uraemic syndrome ; Unpasteurised cheese
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A cluster of four patients (1 girl, 3 boys) from a French village (2,000 inhabitants) had acute haemolytic uraemic syndrome (HUS) between March 1992 and May 1993. All had prodromes with fever and diarrhoea, then acute renal failure, anaemia, schistocytosis and thrombocytopenia. Peritoneal dialysis was carried out in three children (duration 3 – 12 days). The verotoxin VT2 gene was identified by polymerase chain reaction in the stools of two children. Some days prior to the diarrhoea, all children had eaten a cheese made with unpasteurised mixed cows’ and goats’ milk from the same farm. A case control study showed that the occurrence of HUS was linked to the consumption of this milk product (P = 0.006). The VT 2 gene was isolated from the cheese and from the stools of goats and cows from the farm, but not from the stools of farm employees.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00862079
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  • 4
    Electronic Resource
    Electronic Resource
    Renal amyloidosis in juvenile chronic arthritis: evolution after chlorambucil treatment (1990)
    Springer
    Pediatric nephrology 4 (1990), S. 463-469 
    Details
    ISSN: 1432-198X
    Keywords: Juvenile chronic arthritis ; Renal amyloidosis ; Chlorambucil ; Electron microscopy ; Protein AA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Over a 22-year period, eith patients affected with severe systemic or polyarticular juvenile chronic arthritis (JCA) developed systemic amyloidosis with nephrotic syndrome. They were treated with chlorambucil over 5–192 months (mean=44 months). With treatment, an abrupt decrease in the severity of JCA was observed in six patients but two patients were chlorambucil resistant. After a mean follow-up period of 10 years from onset of renal symptoms, one chlorambucil-resistant patient died of end-stage renal failure; two patients have a persistent nephrotic syndrome; and five patients are free from proteinaria, of whom one has developed hypertension. A good correlation was observed between the response of the rheumatic disease to chlorambucil treatment and the clinical course of renal symptoms. Fourteen renal biopsies were performed in these eight patients. In all, amyloid deposits were of the AA type, which persisted on repeat biopsies. In addition, 15%–60% of glomeruli had become globally sclerotic by the second or third biopsies. At the ultrastructural level, modifications in the structure of amyloid deposits and reparative changes of the glomeruli, characterized by partial restoration of glomerular architecture, were observed in three patients with a favourable clinical course.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00869821
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  • 5
    Electronic Resource
    Electronic Resource
    Cluster of cases of haemolytic uraemic syndrome due to unpasteurised cheese (1996)
    Springer
    Pediatric nephrology 10 (1996), S. 203-205 
    Details
    ISSN: 1432-198X
    Keywords: Haemolytic uraemic syndrome ; Unpasteurised cheese
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A cluster of four patients (1 girl, 3 boys) from a French village (2,000 inhabitants) had acute haemolytic uraemic syndrome (HUS) between March 1992 and May 1993. All had prodromes with fever and diarrhoea, then acute renal failure, anaemia, schistocytosis and thrombocytopenia. Peritoneal dialysis was carried out in three children (duration 3–12 days). The verotoxin VT2 gene was identified by polymerase chain reaction in the stools of two children. Some days prior to the diarrhoea, all children had eaten a cheese made with unpasteurised mixed cows' and goats' milk from the same farm. A case control study showed that the occurrence of HUS was linked to the consumption of this milk product (P=0.006). The VT 2 gene was isolated from the cheese and from the stools of goats and cows from the farm, but not from the stools of farm employees.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00862079
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    L'électrodissolution d'une poudre de galène en milieu d'acétate d'ammonium et d'acide chlorhydrique (1988)
    Springer
    Journal of applied electrochemistry 18 (1988), S. 304-311 
    Details
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Abstract A practical type of electrode has been tested for the anodic dissolution of lead sulphide. This is a polypropylene bag that handles the powder mounted on a graphite anode. Performance of this electrode has been evaluated in ammonium acetate and in hydrochloric acid with glycine. Potentiokinetic, potentiostatic and galvanostatic methods have been used for this investigation. XPS, X-ray diffraction and atomic absorption have been used to identify and quantify the products of electrolysis. The addition of acetic acid and organic products inhibit the anodic dissolution in ammonium acetate solution. Hydrochloric acid with glycine solution has better performance as electrolyte than ammonium acetate solution.
    Notes: Résumé Un modèle d'électrode à caractère pratique est proposé pour la dissolution anodique du sulfure de plomb. Il s'agit d'une poudre de PbS introduite dans un sac monté sur une électrode de graphite. Une évaluation de ses performances est faite dans des conditions trouvées optimales pour une électrode massive; soit l'acétate d'ammonium et l'acide chlorhydrique contenant de la glycine. Son comportement est étudié en fonction de la température et de la concentration de l'électrolyte. Les techniques potentiocinétiques, potentiostatiques et galvanostatiques ont été utilisées pour cette étude. Les produits de réaction sont analysés par différent méthodes telles que ESCA, diffraction aux rayonsX et l'absorption atomique. L'addition d'acide acétique et des produits organiques ne favorisent pas la dissolution en milieu d'acétate d'ammonium. L'acide chlorhydrique dosé avec la glycine se révèle être un meilleur support électrolytique que l'acétate d'ammonium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01009279
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