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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 6 (1984), S. 16-20 
    ISSN: 1279-8517
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusion En dépit de ces multiples travaux, il persiste d'énormes contradictions et beaucoup de points flous. Les travaux ont essentiellement débouché sur des observations macroscopiques, et les conséquences des effets mécaniques n'ont pas été évalués à l'échelle histologique, dans l'intimité du cartilage. Toute recherche à venir doit s'orienter vers une analyse plus précise des modifications histologiques et biochimiques. Cette approche biomécanique présente un intérêt fondamental en clinique qui doit déboucher sur une meilleure compréhension d'affection telle que l'épiphysiolyse (le rôle mécanique du ring périchondrial doit être précisé), les traumatismes du cartilage de croissance, où il est difficile sur le plan expérimental de retrouver la classification de Salter, et dans le domaine des inégalités de longueur des membres, où l'on ne connaît pas précisément les effets de la distraction sur le cartilage.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 6 (1984), S. 53-61 
    ISSN: 1279-8517
    Keywords: Epiphyseal plate ; Cell dynamics ; Biomechanics ; Growth regulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs analysent le comportement biomécanique du cartilage de croissance à plusieurs niveaux. Sur le plan histologique ils montrent le rôle joué dans la croissance par les différentes couches cellulaires. La vitesse de croissance des os longs est bien connue chez les animaux et difficile à apprécier chez l'homme. Les facteurs intervenant dans la régulation mécanique du cartilage sont analysés en fonction des contraintes en compression et en détraction. Les autres facteurs (périoste et muscle) sont rapportés. L'analyse de la littérature montre combien le comportement mécanique et les facteurs régissant la croissance sont mal connus et mériteraient un effort de recherche conjugué pour mieux comprendre la portée des gestes chirurgicaux en orthopédie infantile.
    Notes: Summary The authors analyze at several levels the biomechanical activity of the epiphyseal plate. From a histologic point of view, they show the role played by the different cell layers in growth. The rapid growth of long bones is well known in animals, not entirely in human beings. The factors involved in mechanical regulation of the epiphyseal plate are analyzed according to distraction and compression stresses. Other factors have also been reported (periosteum and muscle). Analysis of the literature reveals that biomechanical activity and the factors managing growth are not well known yet. A combined effort should be made to obtain better understanding of the surgical procedures carried out in pediatric orthopedics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 2 (1979), S. 89-91 
    ISSN: 1279-8517
    Keywords: biomatériaux ; vitrocéramiques ; os
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Résumé Après avoir déterminé les caractéristiques physicochimiques des vitrocéramiques pour utilisation en orthopédie, les auteurs ont procédé à leur implantation dans différents segments osseux de lapin. Les prélèvements effectués entre 1 et 6 mois mettent en évidence une colonisation osseuse de bonne qualité au centre et en périphérie de l'implant.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 145 (1986), S. 320-322 
    ISSN: 1432-1076
    Keywords: Lysosomal storage disease ; Sialic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a 5-year-old boy, an early onset psychomotor retardation with nonprogressive ataxia and without dysmorphic features, associated with lysosomal storage disease found on ultrastructural examination of the conjunctiva, led to the diagnosis of Salla disease. This was supported by a tenfold excretion of urinary free sialic acid, without abnormal oligosacchariduria or anomaly in lysosomal enzymes. This boy is a native of Southern France. Screening of urinary sialic acid has to be introduced in aetiological investigations of patients with apparently non-progressive psychomotor retardation associated with ataxia or dystonic movements.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Archives of Biochemistry and Biophysics 303 (1993), S. 67-73 
    ISSN: 0003-9861
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 25 (2002), S. 0 
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The metabolic consequences of long-term carbohydrate depletion have been well documented in many sink organs but not extensively in fruit. Therefore, in the present study the response to sugar limitation in tomato fruit (Lycopersicon esculentum Mill.) was investigated at two developmental stages; during the cell division and cell expansion phases. First, the response in excised fruit cultured in vitro was characterized. Sugar depletion caused an arrest of growth and an exhaustion of carbon reserves. The proteins that were degraded and the nitrogen released was transiently stored as asparagine and glutamine in both developmental stages and also as γ -aminobutyric acid (GABA) in expanding fruit. Fruit at the cell division stage appeared to be more sensitive to sugar limitation. The response to sugar depletion was then characterized in fruit from plants submitted to extended darkness. In planta, the effects of sugar-limitation were similar to those described in vitro but much more attenuated, especially in expanding fruit, which still accumulated dry matter. The expression of cell cycle genes, sugar- and nitrogen-related genes was reduced by darkness. Only asparagine synthetase gene expression was induced in both dark-treated fruit. Together the present data revealed that the effects of the carbon limitation are more pronounced in the youngest fruits as it is probably controlled by the relative sink strength of the fruit.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 14 (1979), S. 1694-1706 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract New porous vitroceramic materials have been prepared by the controlled crystallization of calcium aluminophosphate foam glasses for use in prosthetic bone replacement. The technique of elaboration was developed using DTA measurements. A study was made of their principal properties: porosity, average pore diameter, interconnections between the pores and mechanical characteristics. The biological results are also briefly described.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 18 (1980), S. 396-400 
    ISSN: 1741-0444
    Keywords: Epiphyseal plate ; Growth rate ; Strain control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A method for analysis of growth activity in long bones is presented. An external device composed of two force transducers was fixed on the femur of young rabbits on both sides of the epiphyseal plate. Periodical measurements of axial force variation and bone elongation have been made. Preliminary results have been presented and analysed. The possibility of clinical application, especially in control of the bone growth rate, has been discussed.
    Type of Medium: Electronic Resource
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