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  • 1
    Electronic Resource
    Electronic Resource
    The effects of thiopentone and propofol on upper airway integrity (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 43 (1988), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: One hundred and fifty-eight unpremedicated patients scheduled for elective surgery were allocated randomly to receive an unsupplemented induction dose of thiopentone or propofol. Visualisation of the vocal cords by standard laryngoscopy was possible more often after propofol (p 〈 0.01). Pharyngeal and laryngeal reactivity was similarity depressed more frequently.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1988.tb04146.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Plasma Cortisol and blood sugar following minor surgery under intravenous anaesthetics (1974)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 29 (1974), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1974.tb00717.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Tracheal intubating conditions after induction with sevoflurane 8% in children (2000)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 55 (2000), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We studied tracheal intubating conditions in 120 healthy children, aged 3–12 years, in a blinded, randomised clinical trial. Children were randomly allocated to one of three groups: group PS, propofol 3 mg.kg−1 and succinylcholine 1 mg.kg−1 (n = 40); group PA, propofol 3 mg.kg−1 and alfentanil 10 µg.kg−1 (n = 40); group SF, sevoflurane 8% in 60% nitrous oxide in oxygen for 3 min (n = 40). Tracheal intubating conditions were graded according to ease of laryngoscopy, position of vocal cords, coughing, jaw relaxation and movement of limbs. Overall intubating conditions were acceptable in 39 of 40 children in the propofol/succinylcholine group, 21 of 40 children in the propofol/alfentanil group and 35 of 40 children in the sevoflurane group. Children receiving propofol and succinylcholine or sevoflurane had better intubating conditions overall than those given propofol and alfentanil (p 〈 0.01). In conclusion, anaesthetic induction and tracheal intubation using sevoflurane 8% for 3 min is a satisfactory alternative to propofol with succinylcholine in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2000.01470.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Reversal of neuromuscular block (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 39 (1984), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effect on heart rate of different rates of injection (10 seconds, 1, 3 und 5 minutes) of a fixed dose (neostigmine 2.5 mg and atropine 1.2 mg) and a weight-related dose (neostigmine 50 μg/kg and atropine 25 μg/kg) of neostigmine-atropine mixture given for the reversal of residual competitive neuromuscular block was studied in 196 healthy adult patients. In both series slow injection lessened and delayed the initial rise in heart rate. The subsequent fall in heart rate was less when the drugs were injected over 3 min compared with the 10 seconds and 1 minute injection groups but when given over 5 minutes there was a steady fall in heart rate, more so with the weight-related dose. It is recommended that a neostigmine and atropine mixture should be administered over 3 min.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1984.tb06521.x
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  • 5
    Electronic Resource
    Electronic Resource
    Epidural infusion of alfentanil or diamorphine with bupivacaine in labour—a dose finding study (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 50 (1995), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Following induction of epidural analgesia with 0.375% bupivacaine, 120 healthy parturients were randomly assigned in a double blind fashion to one of eight infusion groups. All received 8ml.h-1 of0.125% bupivacaine either alone (control group), or with alfentanil at 133, 266 or 400μg.h-1 (groups A1-A3) or with diamorphine at 133, 266, 400 or 533μg.h1 (groups D1-D4). Significantly longer top-up intervals were achieved with the two highest doses of both alfentanil and diamorphine when compared with bupivacaine alone (p〈0.01), making the minimum effective doses 266 μg.h-1 of alfentanil and 400 ng.h-1 of diamorphine. Perineal analgesia was better in all the opioid groups compared with the control group (p 〈 0.05). The intensity of motor block was greater in the control group (p 〈 0.05). The incidence of pruritus did not differ between groups. The highest dose of diamorphine caused significantly more nausea. No significant neonatal side-effects were demonstrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1995.tb05996.x
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  • 6
    Electronic Resource
    Electronic Resource
    Cerebral metabolism following brain injury (1980)
    Springer
    Acta neurochirurgica 53 (1980), S. 39-46 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Acid-base parameters and oxygen tension were studied in arterial blood and and lumbar CSF of 45 subjects in three groups of controls, head injuries, and postoperative cases. CSF in both groups of head injury and postoperative cases showed changes of metabolic acidosis with the arterial blood changes of respiratory alkalosis. Both groups had significant hypoxaemia. CSF acidosis is an indication of cerebral metabolic disturbance. It is proportional to the severity of brain damage, and permits a prognosis for further clinical progress. It is recommended that patients with severe brain lesions should be put on controlled ventilation to relieve them of respiratory overwork and to combat cerebral oedema.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02074519
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    Paper (German National Licenses)
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