ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The anomeric configuration of the glycosidic bond in lumazine N1-(2′-deoxy-D-ribonucleosides) 1-6 was investigated by NOE difference spectroscopy. The former configurational assignment of the α - and β -D-anomers 1 and 2, 3 and 4, and 5 and 6, respectively, has to be reversed to be in agreement with the physical data. Additional proof is presented by X-ray analysis of 3 and 6. Chemical interconversions of 1-(2′-deoxy-β-D-ribofuranosyl)-6,7-diphenyllumazine (6) into 2,3′ -anhydrolumazine 2′-deoxyribonucleosides 16 and 17 are also in agreement with the revised anomeric configuration.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19920750427
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