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  • 1
    Electronic Resource
    Electronic Resource
    Lipid Hydrolysis in Unblanched Frozen Peas (Pisum sativum) (1966)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 31 (1966), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Data on hydrolytic changes in the lipids of unblanched (enzymatically active) peas in the range –5 to –20°C are presented. The Q10 value for the formation of free fatty acids between these temperatures is about 2.5. The corresponding value for development of off-flavor is about 3.0. Both values are considerably lower than those typical for deteriorative non-enzymatic reactions in blanched vegetables.Gas chromatographic analysis of the free fatty acid fraction demonstrates further that there is an apparent preference for hydrolysis of polyunsaturated acids. This tendency is especially evident in the lower part of the temperature range studied. A corresponding increase of the proportion of saturated acids in the unhydrolyzed fat can be shown. No net change of any single acid in the combined lipid fractions is observed, except for linoleic and linolenic acids, which decrease somewhat after long storage at the higher temperatures. This indicates a substantial breakdown into smaller molecules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1966.tb01891.x
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  • 2
    Electronic Resource
    Electronic Resource
    Occupational skin disease in Sweden – a 12-year follow-up (2005)
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Contact dermatitis 53 (2005), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this project was to study the long-term prognosis of occupational skin diseases in Sweden. In 1999, a questionnaire was sent to 623/655 individuals who in 1987 reported occupational skin disease to the Social Insurance Office. 394 answered the questionnaire, and 123 non-responders were interwiewed by telephone, giving 517 participants (83%), 323 females and 194 males. 85% reported skin symptoms after 1987, 70% during the previous year. 28% considered themselves recovered, of those with nickel allergy only 12%. In a logistic regression model, skin atopy was the strongest unfavourable factor for the prognosis followed by contact allergy and female sex. 66% had consulted a doctor after 1987 and the majority, 82%, had performed occupational changes – most common was change of jobs, 44%. Those who had changed jobs reported less sick leave. The conclusion is that occupational skin diseases have a clear tendency to end up as chronic conditions with a majority reporting symptoms at a 12-year follow-up. The skin disease had influenced the occupational situation for the majority (82%) and for 15% resulted in exclusion from the labour market through unemployment or disability pension.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0105-1873.2005.00731.x
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  • 3
    Electronic Resource
    Electronic Resource
    Epidemiology of occupational accidents
    Amsterdam : Elsevier
    Journal of Occupational Accidents 6 (1984), S. 129 
    Details
    ISSN: 0376-6349
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Technology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0376-6349(84)90043-9
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  • 4
    Electronic Resource
    Electronic Resource
    Vertebral defects in fourhorn sculpin, Myoxocephalus quadricornis L., exposed to heavy metal pollution in the Gulf of Bothnia (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 33 (1988), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Vertebral defects in adult fourhorn sculpin were used to trace heavy metal pollution in the Gulf of Bothnia (Baltic Sea). From 1978 to 1984 a total of 9789 specimens from 22 localities were X-rayed and analysed for vertebral deformities, e.g., scoliosis, deformation and/or dislocation of individual vertebrae, etc. The frequency of fish with vertebral defects ranged between 4.3 and 39.7%, the highest frequencies being found in the vicinity of a metal ore smeltery (Rönnskärsverken) emitting heavy metals and arsenic. The possible influence of genetic factors, migration, sex, size, age and parasitic infections on the results are discussed and evaluated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.1988.tb05496.x
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  • 5
    Electronic Resource
    Electronic Resource
    The administration of desmopressin by nasal spray: a dose-determination study in patients with mild haemophilia A or von Willebrand's disease (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Haemophilia 1 (1995), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Desmopressin is an important haemostatic agent in many types of bleeding disorders. The intranasal route for administration of desmopressin has attracted much interest because it is convenient and makes self-treatment possible. In the present study the effects of three doses (300, 450 and 600 μg) of desmopressin delivered by nasal spray and those of 0.3 μg/kg injected intravenously were compared in five patients with haemophilia A and 11 with von Willebrand's disease. There was no statistically significant difference in peak VIII:C concentration in the haemophilia patients and no difference in peak vWF concentration in von Willebrand patients between the four desmopressin dosages. Bleeding time response was comparable after all four dosages. We recommend a spray dosage of 300 μg for home treatment. As cover for major surgery or in connection with severe bleedings, however, intravenous administration is to be recommended.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2516.1995.tb00047.x
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  • 6
    Electronic Resource
    Electronic Resource
    A pharmacoscintigraphic evaluation of oral budesonide given as controlled-release (Entocort) capsules (2003)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 17 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims : To investigate the gastrointestinal pharmacokinetics of controlled-release (Entocort) and standard budesonide capsules.Methods : Six Crohn's disease patients and eight healthy controls were given controlled-release capsules containing budesonide and an inert 111In label, following breakfast. In the patients, a standard capsule containing deuterium-labelled budesonide was given simultaneously. In the controls, on a separate occasion, the controlled-release capsules were given in the fasting state. Gastrointestinal transit was recorded by a gamma camera. Plasma budesonide and deuterium-labelled budesonide were used to estimate drug release, and urine cortisol was used to assess systemic effects.Results : Budesonide delivery to the ileo-colonic region was significantly greater after the intake of the controlled-release capsules [69%; 95% confidence interval (CI), 54–84] than after the standard capsules (30%; 95% CI, 15–45) (P = 0.005). Fasting had little impact on uptake. The transit and pharmacokinetics of budesonide were similar in both subject groups, although systemic availability was higher in patients (21%; 95% CI, 13–33) than in controls (12%; 95% CI, 10–14) (P = 0.009). Urinary cortisol was, however, similar in both groups.Conclusions : A major fraction of budesonide is released in the ileum and throughout the colon, the intended target for the controlled-release formulation. The prandial state has little effect on budesonide uptake.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2003.01426.x
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  • 7
    Electronic Resource
    Electronic Resource
    Reply
    Amsterdam : Elsevier
    Trends in Genetics 10 (1994), S. 114-115 
    Details
    ISSN: 0168-9525
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0168-9525(94)90205-4
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  • 8
    Electronic Resource
    Electronic Resource
    A flexible collector system for ISOL experiments
    Amsterdam : Elsevier
    Nuclear Instruments and Methods 111 (1973), S. 431-434 
    Details
    ISSN: 0029-554X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0029-554X(73)90198-5
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  • 9
    Electronic Resource
    Electronic Resource
    The decay of ^6^2"2"9Cu"3"3
    Amsterdam : Elsevier
    Physica 42 (1969), S. 303-308 
    Details
    ISSN: 0031-8914
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0031-8914(69)90022-6
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  • 10
    Electronic Resource
    Electronic Resource
    Uptake and distribution of calcium, magnesium and potassium in cucumber of different age (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 57 (1983), S. 0 
    Details
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Uptake and distribution of Ca+, Mg2+ and K2+ were investigated in plants of cucumber (Cucumis sativus L. var. Cila) which had been cultivated for 12, 19, 32, or 53 days in complete nutrient solution with 1.0 mM Ca2+, 2.0 mM Mg2+ and 2.0 mM K+. The + concentration was about the same in roots and shoots, while the Ca2+ and Mg2+ concentrations were low in roots compared to shoots. The K+ concentration decreased with increasing leaf age, while the Ca2+ and Mg2+ concentrations increased, except in older plants with flowers and fruits, where an increased concentration was found in the youngest leaves. This is discussed in connection with increased indoleacetic acid (IAA) synthesis in the shoot. Excision of leaves at different levels from 21-day-old plants, followed by uptake for 24 h from the nutrient solution on days 22 and 23, resulted in no immediate reduction in Ca2+ (45Ca) uptake. Transport of Ca2+ increased to leaves above and below the excision point and total Ca2+ uptake remained at the same level as for the intact plant. It is suggested that regulation of Ca2+ uptake is primarily achieved in the root while the distribution in the shoot is regulated by the accessability of negative binding sites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1399-3054.1983.tb02764.x
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