ISSN:
1573-2576
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Levels of rat liver mRNA for the plasma proteins albumin, apolipoprotein E, transthyretin, transferrin,α 1-acid glycoprotein, major acute-phaseα 1-protein, and theΒ-chain of fibrinogen were measured after intraperitoneal injection of interleukin-1α (IL-1). A maximum response of mRNA levels for most of the plasma proteins studied was reached between 6 and 10 h after injection of IL-1. The results suggest that at the dosage used, IL-1 alone does not elicit a typical acute-phase response of the plasma protein-synthesizing system of the liver.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00914322
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