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  • 1
    Electronic Resource
    Electronic Resource
    Small-intestinal abnormalities in cystic fibrosis patients (1991)
    Springer
    European journal of pediatrics 150 (1991), S. 824-828 
    Details
    ISSN: 1432-1076
    Keywords: Absorption ; Alkaline phosphatase ; Cystic fibrosis ; Digestion ; Disaccharidase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A survey is given of the pathophysiology of the main alterations in the small intestine of cystic fibrosis patients. Special attention is paid to the understanding of meconium ileus in the fetus and the newborn, the repercussion of duodenal acidity on the duodenal mucosa and the intraduodenal digestion, and primary and secondary biochemical alterations in the secretory-digestive-absorptive function of the small-intestinal mucosa. The meconium equivalent syndrome and its connection with the atypical course of intussusception and appendiceal perforation with silent pelvic abscess are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01954999
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Specific decrease of anti-pseudomonal IgA after anti-pseudomonal therapy in cystic fibrosis (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 157-160 
    Details
    ISSN: 1432-1076
    Keywords: Cystic fibrosis ; Pseudomonas aeruginosa ; IgA antibodies ; IgG antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In patients with cystic fibrosis (CF) and chronic colonisation withPseudomonas aeruginosa, specific anti-pseudomonal IgG and IgA, as well as serum immunoreactive protein C, WBC and differential count, ESR, pulmonary function and chest radiograph score were determined before and after a 2 week intravenous course of anti-pseudomonal antibiotics in 32 cases of acute exacerbation of pulmonary infection. Specific anti-pseudomonal IgA but not specific anti-pseudomonal IgG decreased significantly after treatment. Log of anti-pseudomonal IgA but not log anti-pseudomonal IgG correlated well with disease severity as assessed by the Brasfield chest radiograph score (r 0.57), forced expiratory volume in 1 s (r 0.6) as well as C-reactive protein (r 0.62).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01991922
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  • 3
    Electronic Resource
    Electronic Resource
    Specific decrease of anti-pseudomonal IgA after anti-pseudomonal therapy in cystic fibrosis (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 157-160 
    Details
    ISSN: 1432-1076
    Keywords: Key words Cystic fibrosis ; Pseudomonas aeruginosa ; IgA ; antibodies ; IgG antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In patients with cystic fibrosis (CF) and chronic colonisation with Pseudomonas aeruginosa, specific anti-pseudomonal IgG and IgA, as well as serum immunoreactive protein C, WBC and differential count, ESR, pulmonary function and chest radiograph score were determined before and after a 2 week intravenous course of anti-pseudomonal antibiotics in 32 cases of acute exacerbation of pulmonary infection. Specific anti-pseudomonal IgA but not specific anti-pseudomonal IgG decreased significantly after treatment. Log of anti-pseudomonal IgA but not log anti-pseudomonal IgG correlated well with disease severity as assessed by the Brasfield chest radiograph score (r 0.57), forced expiratory volume in 1 s (r 0.6) as well as C-reactive protein (r 0.62).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050268
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  • 4
    Electronic Resource
    Electronic Resource
    Response to bronchodilators in clinically stable 1-year-old patients with bronchopulmonary dysplasia (1997)
    Springer
    European journal of pediatrics 157 (1997), S. 75-79 
    Details
    ISSN: 1432-1076
    Keywords: Key words Bronchopulmonary dysplasia Bronchodilators ; Pulmonary function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Bronchodilators are often used in the treatment of patients with bronchopulmonary dysplasia (BPD). However, few studies evaluate their efficacy in patients with stable disease beyond the newborn period. Therefore, pulmonary function was measured before and after aerosol treatment with salbutamol (0.25 ml Ventolin 0.5%) and subsequently after aerosol with ipratropium bromide (0.25 ml Atrovent 0.025%). Studies were performed at the corrected postnatal age of 52±2 weeks in 52 patients who had been ventilated after birth because of newborn lung disease. Twenty-two of these 52 patients had developed BPD. Pulmonary function was measured after sedation and using the PEDS system. Expiratory resistance (median 52.1 versus 39.1 cmH2O/l/s; P〈.008) and inspiratory resistance (median 42.5 vs 27.8 cmH2O/l/s; P〈.04) were significantly worse in BPD patients at the age of 1 year. Half of the BPD patients had a decrease in pulmonary resistance after salbutamol. However, there was no statistically significant decrease in pulmonary resistance after salbutamol or ipratropium in the BPD patients as a group. After salbutamol pulmonary resistance significantly worsened in the patients who did not develop BPD. Conclusion Although individual patients may benefit, routine administration of bron chodilators seems not warranted in stable BPD patients at the age of 1 year.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050771
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  • 5
    Electronic Resource
    Electronic Resource
    Primary ciliary dyskinesia: evolution of pulmonary function (1998)
    Springer
    European journal of pediatrics 157 (1998), S. 422-426 
    Details
    ISSN: 1432-1076
    Keywords: Key words Primary ciliary dyskinesia ; Lung function ; Bronchodilators
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pulmonary function tests were obtained in 11 patients with primary ciliary dyskinesia. Their mean age was 15 years (range 6–32). Their pulmonary function was obstructive, with a vital capacity (mean ± SD) of 75% ± 20% predicted, a forced expiratory volume in 1s (FEV1) of 63% ± 20% predicted and a raised residual volume of 169% ± 50% predicted. After inhalation of 200 μg of salbutamol the mean change in FEV1 was +13.2% ± 9.6% of the baseline value. In the 10 oldest patients, lung function had been measured at regular intervals during 3–20 years. Interestingly, during childhood and adolescence the evolution was not unfavourable: vital capacity increased by 8% ± 20% and FEV1 remained stable (mean change 0.3% ± 12%). Only 2 patients had an unfavourable evolution. Conclusion At time of diagnosis, patients with primary ciliary dyskinesia have partially reversible obstructive airway disease. During regular follow up and therapy, there is no evidence of a further decline in lung function. Patients with associated immunodeficiency or important damage at the start of therapy may have a worse prognosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050843
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Radionuclide bone imaging in toddler's fracture (1991)
    Springer
    European journal of pediatrics 150 (1991), S. 166-169 
    Details
    ISSN: 1432-1076
    Keywords: Toddler's fracture ; Radionuclide bone imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Seven cases of toddler's fracture are reported. The value of radionuclide bone imaging in helping to establish this diagnosis is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01963558
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  • 7
    Electronic Resource
    Electronic Resource
    A right lower quadrant mass in cystic fibrosis: A diagnostic challenge (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 329-331 
    Details
    ISSN: 1432-1076
    Keywords: Cystic fibrosis ; Appendiceal abscess ; Distal intestinal obstruction syndrome ; Meconium ileus equivalent
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a cystic fibrosis (CF) patient a right lower quadrant (RLQ) mass may be a difficult diagnostic problem. Most frequently it is due to a distal intestinal obstruction syndrome [8, 12] also called meconium ileus equivalent [11], but the possibility of intussusception and appendiceal abscess should also be considered. We describe three CF patients with an appendiceal abscess seen in a 4-year period. All three patients had a palpable RLQ mass. Chronicity and obliteration of the appendiceal lumen with abnormally viscid mucus may lead to concealed perforation and be responsible for the atypical presentation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02113250
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  • 8
    Electronic Resource
    Electronic Resource
    Croup: a review (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 432-436 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02029350
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Croup: A review (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 432-436 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02029350
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Melanoma-associated paraneoplastic retinopathy: case report and review of the literature (1997)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 137 (1997), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 51-year-old white male suffering from metastatic malignant melanoma of the skin presented with lymph node metastases and paraneoplastic retinopathy 4 years after resection of the primary tumour. There were no cerebral metastases. Ocular symptoms consisting of night blindness and sensations of ‘shimmering lights’ persisted after total resection of the inguinal lymph node metastases and administration of dacarbazine and prednisone. Perimetry of both eyes was abnormal with concentric restriction. Electroretinography showed significantly reduced amplitudes in both eyes. Only 11 patients with melanoma-associated retinopathy (MAR) have been described. High titres of autoantibodies against whole retina extract were detected by enzyme-linked immunosorbent assay (ELISA) reactions. Indirect immunohistochemistry showed strong autoantibody activity against retinal bipolar cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1997.18701958.x
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