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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 39 (1983), S. 1295-1297 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Porcine liver β-D-glucose dehydrogenase has been isolated using Triton X-114 to release it from the endoplasmic reticulum. The purified enzyme contains a limited amount (1.7%) of lipid material, including cholesterol, fatty acids, mono and diglycerides, phosphatidylcholine, phosphatidylethanolamine, and cholesterol esters. This enzyme is a tetrameric protein containing an extensive number of hydrophobic residues. This form of glucose dehydrogenase is capable of turning over both β-D-glucose and α-D-glucose-6-phosphate in vivo as indicated from a steady state kinetic analysis at 37°C.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 53 (1997), S. 1153-1154 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 38 (1982), S. 1046-1047 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A metal analysis of bovine hepatic gluconolactonase indicates the presence of at least 1 atom of tightly bound zinc per enzyme subunit in this hexameric protein. Other divalent metals are present in lesser quantities and are subject to removal by EDTA. Activation energies for the manganese and magnesium catalyzed reactions are 5.3 and 11.0 kcal/mole, respectively.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1439-6327
    Keywords: Key words Performance  ;  Hypoxaemia  ;   $\dot V$O2peak  ;   Hypobaria  ;  Women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study examined the effect of mild hypobaria (MH) on the peak oxygen consumption ( O2peak) and performance of ten trained male athletes [ (SEM); O2peak = 72.4 (2.2) ml · kg−1 · min−1] and ten trained female athletes [ O2peak = 60.8 (2.1) ml · kg−1 · min−1]. Subjects performed 5-min maximal work tests on a cycle ergometer within a hypobaric chamber at both normobaria (N, 99.33 kPa) and at MH (92.66 kPa), using a counter-balanced design. MH was equivalent to 580 m altitude. O2peak at MH decreased significantly compared with N in both men [− 5.9 (0.9)%] and women [− 3.7 (1.0)%]. Performance (total kJ) at MH was also reduced significantly in men [− 3.6 (0.8)%] and women [− 3.8 (1.2)%]. Arterial oxyhaemoglobin saturation (SaO2) at O2peak was significantly lower at MH compared with N in both men [90.1 (0.6)% versus 92.0 (0.6)%] and women [89.7 (3.1)% versus 92.1 (3.0)%]. While SaO2 at O2peak was not different between men and women, it was concluded that relative, rather than absolute, O2peak may be a more appropriate predictor of exercise-induced hypoxaemia. For men and women, it was calculated that 67–76% of the decrease in O2peak could be accounted for by a decrease in O2 delivery, which indicates that reduced O2 tension at mild altitude (580 m) leads to impairment of exercise performance in a maximal work bout lasting ≈ 5 min.
    Type of Medium: Electronic Resource
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