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  • 1
    Electronic Resource
    Electronic Resource
    HLA-G deletion polymorphism and pre-eclampsia/eclampsia (1995)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 102 (1995), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To investigate a HLA-G deletion polymorphism in pre-eclamptic pedigrees and the general population.Design A population association study of HLA-G genotypes from pre-eclamptic/eclamptic patients and control groups.Setting Analyses undertaken in the School of Biological Sciences, Macquarie University. Patients were from Royal Women's Hospital, Melbourne, and controls were from Westmead Hospital and Macquarie University, Sydney.Subjects One hundred and ninety-six individuals, consisting of 29 pre-eclamptic/eclamptic (PE/E) patients, 13 individuals born of a PE/E pregnancy, 46 blood relatives of PE/E patients, 21 husbands of PE/E patients, 25 women normotensive in first pregnancy, 15 husbands of women normotensive in first pregnancy and 47 staff and students of Macquarie University.Results Genotypic and gene frequencies were not significantly different in the seven groups examined.Conclusion There is no detectable relationship between susceptibility to pre-eclampsia or being born of a pre-eclamptic pregnancy and HLA-G genotype.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1995.tb11427.x
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  • 2
    Electronic Resource
    Electronic Resource
    A Serum Protein present in Pregnant Women (1963)
    [s.l.] : Nature Publishing Group
    Nature 200 (1963), S. 892-892 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. Anode at the top of photograph. Starch-gel electrophoresis of two sera from pregnant women at 4.5 V/cm for 14 h in borate buffer (0.0092 M sodium hydroxide, 0.023 M boric acid pH = 8.5) and staining with amido black 10B. (1) Haptoglobin type 11 ; (2) haptoglobin type 22 ; (A) first ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/200892a0
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  • 3
    Electronic Resource
    Electronic Resource
    Directed Genetic Change Model for X Chromosome Inactivation in Eutherian Mammals (1971)
    [s.l.] : Nature Publishing Group
    Nature 230 (1971), S. 292-294 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Random inactivation of one or other of the X chromosomes in female eutherians could have evolved from an ancestral paternal X inactivation, which has been retained in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/230292a0
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  • 4
    Electronic Resource
    Electronic Resource
    Haptoglobin Johnson in Australian Aborigines (1965)
    [s.l.] : Nature Publishing Group
    Nature 208 (1965), S. 694-694 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The haptoglobin phenotypes of the members of the pedigree are indicated in Fig. 1. The starch-gel pattern designated H (for hypohaptoglobinaemia) was very similar to that of the serum of a member of the pedigree reported by Ramot et al.* in which the parents were also Hp 2-1 arid Johnson. Their ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/208694a0
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  • 5
    Electronic Resource
    Electronic Resource
    THE INCIDENCE OF SEVERE PRE-ECLAMPSIA AMONGST MOTHERS AND MOTHERS-IN-LAW OF PRE-ECLAMPTICS AND CONTROLS (1981)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 88 (1981), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In order to distinguish between a maternal, fetal or maternal and fetal genetic predisposition towards severe pre-eclampsia, the first pregnancies of 158 mothers and 160 mothers-in-law of pre-eclamptic women and of matched controls were analysed. Fourteen per cent of mothers of pre-eclamptics were found to have had severe pre-eclampsia, confirming previous suggestions that the condition‘runs in families', in contrast to only a 3% incidence amongst mothers of controls. The incidence in mothers-in-law of both pre-eclamptics and controls was 4%, in full agreement with a maternal genotype hypothesis and suggesting that the fetal genotype plays, at most, only a minor role in the aetiology of severe pre-eclampsia. The data are in agreement with the hypothesis that a single recessive gene acting in the mother could be responsible for severe pre-eclampsia, but multifactorial inheritance is not ruled out. Mild pre-eclampsia showed no such familial tendency, indicating that the mild and severe forms of pre-eclampsia may represent separate pathological entities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1981.tb01304.x
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  • 6
    Electronic Resource
    Electronic Resource
    Phenylephrine in obstetric regional anaesthesia (2003)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 58 (2003), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2003.305912.x
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  • 7
    Electronic Resource
    Electronic Resource
    Patient-controlled epidural fentanyl following spinal fentanyl at Caesarean section (2002)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 57 (2002), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Spinal fentanyl can improve analgesia during Caesarean section. However, there is evidence that, following its relatively short-lived analgesic effect, there is a more prolonged spinal opioid tolerance effect. The effectiveness of postoperative epidural fentanyl analgesia may therefore be reduced following the use of spinal fentanyl at operation. This randomised, double-blind study was designed␣to assess whether patient-controlled epidural fentanyl could produce effective analgesia following 25 µg of spinal fentanyl at operation. Patients undergoing elective Caesarean section received spinal bupivacaine combined with either fentanyl 25 µg (fentanyl group; n = 18) or␣normal saline (saline group; n = 18). Patient-controlled epidural fentanyl was used for postoperative analgesia. The fentanyl group used a mean of 23.4 (SD 14.5) µg.h−1 of fentanyl, compared with 27.0 (10.8) µg.h−1 for the saline group (p = 0.41). Using a 0–100 mm visual analogue score for pain, the maximum pain score recorded at rest for the fentanyl group was median 24 [IQR 15–35] mm, compared with 15 [13–45] mm for the saline group (p = 0.41). The maximum pain score recorded on coughing for the fentanyl group was 29 [24–46] mm, compared with 27 [19–47] mm for the saline group (p = 0.44). Nine of the fentanyl group rated postoperative analgesia as excellent and nine as good, compared with 10 of the saline group who rated it as excellent and eight as good (p = 0.74). Epidural fentanyl can produce effective analgesia following the use of 25 µg spinal fentanyl at Caesarean section.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2002.2366_1.x
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  • 8
    Electronic Resource
    Electronic Resource
    Fetal acidosis, spinal anaesthesia and phenylephrine (2001)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 56 (2001), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2001.02230-24.x
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  • 9
    Electronic Resource
    Electronic Resource
    Ephedrine, phenylephrine and fetal acidosis (2005)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 60 (2005), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.2005.04443.x
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  • 10
    Electronic Resource
    Electronic Resource
    D Adelaide —a New Transferrin Variant in Man (1964)
    [s.l.] : Nature Publishing Group
    Nature 204 (1964), S. 102-102 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Transferrin C is the commonest variant; it is found in all populations. Variants with an electrophoretic mobility faster than C have been given the notation B; slower variants, the notation D. Subscripts distinguish the different B and D variants. __ The difference between C and any one of the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/204102a0
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