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  • 1
    Electronic Resource
    Electronic Resource
    In vitro production of human antigen presenting cells issued from bone marrow of patients with cancer (1997)
    Springer
    Hematology and cell therapy 39 (1997), S. 237-244 
    Details
    ISSN: 1279-8509
    Keywords: Antigen presenting cells ; Human bone marrow ; In vitro production
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the prospect of producing autologous antigen presenting cells (APC) to actively immunize patients with cancer against their own tumor we were interested in the in vitro generation of MC and/or dendritic cells. We observed that the best yielding in CD14+ cells was obtained by adding SCF and GM-CSF into RPMI 1640 completed medium and by using Teflon bags as culture-containers. The others growth factors tested (LIF, IL3 and M-CSF) were useless in term of production of macrophages. After a month of culture we usually obtained an average of 80% of CD14, CD33, CD64, CD11a, CD11b, CD11c and HLA-DR positive cells expressing the MGG staining phenotype of MC. For DC the best association of growth factors combined GM-CSF, IL4 and SCF. Hence we could obtained at least 60% of CD1a+, CD14-, CD54+, CD58+, CD80+ and HLA DR+ dendritic cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00282-997-0237-7
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  • 2
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    Varia Conjectanea (1956)
    Paris : Periodicals Archive Online (PAO)
    Revue de philologie, de littérature et d'histoire anciennes. ser.3:30=82 (1956) 251 
    Details
    ISSN: 0035-1652
    Topics: Classical Studies
    Notes: ARTICLES ORIGINAUX
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:p232-1956-030-00-000003
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  • 3
    Electronic Resource
    Electronic Resource
    Sequential production of leukaemia inhibitory factor by blood cell culture in patients with ARDS (1998)
    Springer
    Intensive care medicine 24 (1998), S. 366-368 
    Details
    ISSN: 1432-1238
    Keywords: Key words Acute respiratory distress syndrome ; Leukaemia inhibitory factor ; Cytokines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Leukaemia inhibitory factor (LIF) is a polyfunctional cytokine integrated in cytokine networks and its concentration has been shown to be elevated in bronchoalveolar lavage fluid of patients with the acute respiratory distress syndrome (ARDS). The aim of our study was to evaluate the production of LIF by culturing blood cells from patients with ARDS. Patients: 8 patients with ARDS, 8 patients with pneumonia and 5 healthy subjects. Measurements and results: The blood samples were taken on day 1 after onset of ARDS. LIF was measured, in the cell-free supernatant, with an enzyme-linked immunosorbent assay after 24 h, 48 h and 72 h of blood cell culture. LIF was detectable in some patients in the ARDS group: at i) at 24 h and 48 h: in 2 patients ii) at 72 h in 4/5 patients (140 ± 231 pg/ml). Only in the 4 patients in whom LIF was measured at 72 h was ARDS associated with the multiple organ dysfunction syndrome. Furthermore, among the 5 patients with ARDS who subsequently died, 4 had a detectable LIF. Conclusions: We have observed that LIF was produced only in ARDS, but not in all patients. The production of LIF seems to be a good indicator of the severity of ARDS. These preliminary results must be confirmed by a larger study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050582
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  • 4
    Electronic Resource
    Electronic Resource
    Dissipative evolution of quantum statistical ensembles and nonlinear response to a time-periodic perturbation (2003)
    Springer
    The European physical journal 36 (2003), S. 573-592 
    Details
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We present a detailed discussion of the evolution of a statistical ensemble of quantum mechanical systems coupled weakly to a bath. The Hilbert space of the full system is given by the tensor product between the Hilbert spaces associated with the bath and the bathed system. The statistical states of the ensemble are described in terms of density matrices. Supposing the bath to be held at some - not necessarily thermal - statistical equilibrium and tracing over the bath degrees of freedom, we obtain reduced density matrices defining the statistical states of the bathed system. The master equations describing the evolution of these reduced density matrices are derived under the most general conditions. On time scales that are large with respect to the bath correlation time $\tau_{B}^{\mathrm{corr}}$ and with respect to the reciprocal transition frequencies of the bathed system, the resulting evolution of the reduced density matrix of the bathed system is of Markovian type. The detailed balance relations valid for a thermal equilibrium of the bath are derived and the conditions for the validity of the fluctuation-dissipation theorem are given. Based on the general approach, we investigate the non-linear response of the bathed subsystem to a time-periodic perturbation. Summing the perturbation series we obtain the coherences and the populations for arbitrary strengths of the perturbation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjb/e2004-00013-5
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  • 5
    Electronic Resource
    Electronic Resource
    Structural and dynamical properties of magnesium microclusters (1991)
    Springer
    The European physical journal 19 (1991), S. 173-176 
    Details
    ISSN: 1434-6079
    Keywords: 36.40. +d ; 31.20.Sy ; 61.50.Cj
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present systematic Density Functional Theory-Local Density Approximation computations for neutral Magnesium clusters Mg n withn≤13. For the smaller sizes the ground state structure is optimized starting from selected symmetries and allowing for relaxation, Jahn-Teller distorsion and spin polarization. For the larger sizes we perform a simulated annealing based on the ab-initio Molecular Dynamics. By the same method, we study the thermal and dynamical properties of Mg10 and Mg16. The general picture emerging from these computations shows that already atn ≈10 these clusters have acquired many characteristic features of metallic Magnesium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01448284
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  • 6
    Electronic Resource
    Electronic Resource
    Mg2PN3 und Ca2PN3 - Phosphor(V)-nitride mit eindimensional unendlichen Ketten eckenverknüpfter PN4-Tetraeder (1997)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 623 (1997), S. 69-74 
    Details
    ISSN: 0044-2313
    Keywords: Alkaline earth metals ; phosphorus nitrides ; synthesis ; crystal structure ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Mg2PN3 and Ca2PN3 - Phosphorus(V) Nitrides with Infinite Chains of Corner Sharing PN4 TetrahedraMg2PN3 and Ca2PN3 have been synthesized by the reaction of the respective metal nitrides with P3N5 at 800°C. The products have been obtained as fine crystalline powders. The crystal structures have been determined on the basic of powder diffraction data. Mg2PN3 (Cmc21, a = 972,64(8), b = 564,30(5), c = 473,02(2) pm, Z = 4) and Ca2PN3 (Cmca, a = 519,14(4), b = 1031,63(8), c = 1128,8(1) pm, Z = 8) contain Mg2+ and Ca2+ ions, respectively, as well as PN3 Zweier chains of corner sharing PN4 tetrahedra. A significant difference of the stretching factor of the PN3 chains has been observed in Mg2PN3 (fs = 0,88) and Ca2PN3 (fs = 1,0).
    Notes: Mg2PN3 und Ca2PN3 wurden durch Reaktion der jeweiligen Metallnitride mit P3N5 bei 800°C als feinkristalline Pulver erhalten. Ihre Kristallstrukturen wurden aus Pulverdaten bestimmt und verfeinert. Mg2PN3 (Cmc21, a = 972,64(8), b = 564,30(5), c = 473,02(2) pm, Z = 4) und Ca2PN3 (Cmca, a = 519,14(4), b = 1031,63(8), c = 1128,8(1) pm, Z = 8) enthalten im Festkörper Mg2+- bzw. Ca2+-Ionen und PN3-Zweierketten eckenverknüpfter PN4-Tetraeder. Es ergeben sich deutlich unterschiedliche Streckungsfaktoren der PN3-Ketten von fs = 0,88 (Mg2PN3) und fs = 1,0 (Ca2PN3).
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19976230112
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