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  • 1
    Electronic Resource
    Electronic Resource
    Management of androgenetic alopecia〈link href="#fn1"〉★〈/link〉 (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 12 (1999), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Androgenetic alopecia (AGA) is the most frequent cause of hair loss affecting up to 50% of men and 40% of women by the age of 50.〈section xml:id="abs1-3"〉〈title type="main"〉MethodsThis paper outlines the current status of diagnosis and offers guidelines for optimal management of AGA in both men and women.〈section xml:id="abs1-4"〉〈title type="main"〉ResultsThe diagnosis of AGA can usually be confirmed by medical history and physical examination alone. A trichogram can be useful to assess the progression of the hair loss. A scalp biospy is diagnostic but usually not required. In women with signs of hyperandrogenism, investigation for ovarian (polycystic ovarian disease) or adrenal (late-onset congenital adrenal hyperplasia) disorders is required. Mild to moderate AGA in men can be treated with oral finasteride or topical minoxidil. Oral finasteride at the dosage of 1 mg/day produced clinical improvement in up to 66% of patients treated for 2 years. The drug is effective for both frontal and vertex hair thinning. Medical treatment with finasteride or minoxidil should be continued indefinitely since interruption of therapy leads to hair loss with return to pretreatment status. Mild to moderate AGA in women can be treated with oral antiandrogens (cyproterone acetate, spironolactone) and/or topical minoxidil with good results in many cases. Hair systems and surgery may be considered for selected cases of severe AGA both in men and in women.〈section xml:id="abs1-5"〉〈title type="main"〉ConclusionsPatients with AGA should be informed about the pathogenesis of the condition. If used correctly, available medical treatments arrest progression of the disease and reverse miniaturization in most patients with mild to moderate AGA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.1999.tb01030.x
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  • 2
    Electronic Resource
    Electronic Resource
    Mucosal contact dermatitis due to instant coffee (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 7 (1981), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A housewife developed recurrent mouth soreness that was resistant to all topical treatments. Flatulence was also a problem at this time. Patch testing revealed a sensitivity to instant coffee (in granule form) and all symptoms regressed when contact ceased. The possible allergen is discussed. There is a need to patch test all patients with ‘idiopathic’ mouth soreness. The importance of keeping records of possible precipitating factors is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1981.tb04084.x
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  • 3
    Electronic Resource
    Electronic Resource
    Occupational contact dermatitis due to quaternium 15 presenting as nail dystrophy (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 25 (1991), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1991.tb01856.x
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  • 4
    Electronic Resource
    Electronic Resource
    Contact dermatitis to one ingredient of Xerumenex ear drops (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 2 (1976), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1976.tb03037.x
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  • 5
    Electronic Resource
    Electronic Resource
    Apparent fragility of African hair is unrelated to the cystine-rich protein distribution: a cytochemical electron microscopic study (2005)
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Experimental dermatology 14 (2005), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract:  A feature of black African hair is an apparent increased fragility of the hair shaft compared to other ethnic groups (as measured by the tensile force needed to break the hair fibre). This has certain similarities to that reported for trichorrhexis nodosa (weathering secondary to physical damage) and trichothiodystrophy [a genetic disorder associated with reduced cystine (sulphur)-rich proteins and increased fragility]. In the present study, the distribution of the cystine-rich proteins in the hair of black Africans was compared to that of Caucasian and Asian volunteers, plus patients with trichorrhexis nodosa and trichothiodystrophy, using transmission electron microscopy and specific silver stains. It was found that the silver staining pattern of the hair shafts of black Africans was similar to that observed for Caucasians, Asians and also patients with trichorrhexis nodosa. The cuticular cells exhibited an electron dense A layer and exocuticle, and in the cortex the microfibrils forming the macrofibres were outlined by electron-dense material. This contrasts with the abnormal distribution of the cystine-rich proteins seen in trichothiodystrophy. This study is the first formal comparison of the cystine-rich proteins in the various racial groups and shows that there is no abnormality in their distribution in black African hair shafts compared to the other ethnic groups. Therefore, the excessive structural damage observed in the African hair shafts is consistent with physical trauma (resulting from grooming) rather than an inherent weakness due to any structural abnormality.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0906-6705.2005.00288.x
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  • 6
    Electronic Resource
    Electronic Resource
    The epidermal cell kinetics of the erythrokeratodermas (1982)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 107 (1982), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The cell proliferation kinetics of the genodermatoses, erythrokeratoderma variabilis (EKV) and symmetrical progressive erytbrokeratoderma (SPE), were studied using flash labelling studies and cell production rates using vincristine.In EKV the results indicated a mildly hyperproliferative state, while in SPE the results, although variable, showed a prominent epidermal hyperproliferation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1982.tb00407.x
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  • 7
    Electronic Resource
    Electronic Resource
    (38) Pili torti (1983)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 109 (1983), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1983.tb11645.x
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  • 8
    Electronic Resource
    Electronic Resource
    A multiparametric approach is essential to define different clinicopathological entities within pseudopelade of Brocq (2003)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 148 (2003), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2003.05277.x
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  • 9
    Electronic Resource
    Electronic Resource
    FINGERNAIL GROWTH IN IDIOPATHIC AND PSORIATIC ONYCHOLYSIS (1971)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 85 (1971), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.— In idiopathic onycholysis, nail growth has been found to be significantly taster than normal. An increase of similar magnitude was found in psoriatic onycholysis. We are unable to say whether increased nail growth is of pathogenic importance or is simply a consequence of onycholysis. The hypothesis that idiopathic onycholysis is “pre-psoriatic” was tested by measuring growth of uninvolved nails in both idiopathic and psoriatic groups; the clinically normal nails of psoriatic patients grew significantly faster, and those in the idiopathic group marginally more slowly than normal. These findings, combined with a significant difference in the fingernails involved in the ony-cholytic process, lead us to conclude that idiopathic onycholysis is not “pre- psoriatic”.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1971.tb14082.x
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  • 10
    Electronic Resource
    Electronic Resource
    Beau's lines in immunobullous disease (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 20 (1995), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1995.tb01347.x
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