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  • 1
    Electronic Resource
    Electronic Resource
    Heterologous expression of the Aspergillus nidulans regulatory gene nirA in Fusarium oxysporum
    Amsterdam : Elsevier
    Gene 109 (1991), S. 155-160 
    Details
    ISSN: 0378-1119
    Keywords: Transformation ; filamentous fungi ; gene regulation ; nitrate assimilation
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0378-1119(91)90602-8
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  • 2
    Electronic Resource
    Electronic Resource
    Erythema multiforme due to pyrazinamide (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 51 (1996), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Drug-induced erythema multiforme is reported with many antimicrobial and antipyretic medications. We present one patient who experienced erythema multiforme and urticaria after administration of pyrazinamide for treatment of cutaneous tuberculosis. The side-effects of pyrazinamide include hepatic or dermatologic disorders, but erythema multiforme has not yet, to our knowledge, been described. Clinical features and discontinuation and reintroduction of the drug led us to consider pyrazinamide the cause of the erythema multiforme, but allergologic studies remained negative, except for the presence of circulating immune complexes. The mechanism of this eruption remains obscure. and definite withdrawal of pyrazinamide seems to be the best therapeutic choice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1996.tb04620.x
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  • 3
    Electronic Resource
    Electronic Resource
    To the editor (1992)
    Springer
    World journal of surgery 16 (1992), S. 545-546 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02104469
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  • 4
    Electronic Resource
    Electronic Resource
    Mortality study among workers producing chromate pigments in France (1995)
    Springer
    International archives of occupational and environmental health 67 (1995), S. 147-152 
    Details
    ISSN: 1432-1246
    Keywords: Epidemiology ; Lung cancer ; Chromate pigments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a follow-up study of 294 men who had worked for at least 6 months in a chromate-producing factory in France between 1958 and 1987, only 16 were lost to follow-up and the number of person-years in the study was 5207. Occupational data were provided by the administration of the plant. The causes of deaths were ascertained from hospital and general practitioners' records. The observed numbers of deaths were compared with the expected numbers based on local rates with adjustment for age, sex and calendar time (standardized mortality ratio, SMR). The overall mortality did not differ significantly from that expected (SMR = 1.20, 95% CI = 0.98–1.47), whereas mortality due to lung cancer was in significant excess (SMR = 3.60, 95% CI = 2.13–5.68). Significantly higher lung cancer SMRs were found for workers whose duration of employment was more than 10 years. A non-significant excess was observed for all forms of digestive tract cancer (SMR = 1.30, 95% CI = 0.60–2.47). There were two cases of brain cancer when 0.24 was expected (SMR = 8.44, 95% CI = 1.02–30.49). No previous report has mentioned an association of brain cancer with chromate pigments; however, because of the small numbers involved, a chance excess should be considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00626345
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  • 5
    Electronic Resource
    Electronic Resource
    Production of food yeast from starchy substrates (1982)
    Springer
    Applied microbiology and biotechnology 15 (1982), S. 232-236 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Fifteen yeast strains were selected for the production of food yeast from starchy substrates. From comparison with the amylolytic yeasts, a strain of Schwanniomyces castellii was selected and its characteristics are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00499962
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  • 6
    Electronic Resource
    Electronic Resource
    Xylanase production in solid-state fermentation: a study of its properties (1985)
    Springer
    Applied microbiology and biotechnology 22 (1985), S. 177-180 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Xylanase production by Aspergillus niger van Tieghem was studied in solid-state cultivation. The screening of substrates was carried out in column incubators aerated with humidified air at 30°C. Results of physiological studies showed that the best yield of xylanase was 2500 U/g dry matter on a mixture of straw+bran 1:1 at 70% of moisture content. In order to compare some properties of the xylanase produced in both liquid and solid cultures, A. niger was also grown on xylan in submerged cultures. The enzymes produced in solid and liquid cultures have an optimum pH of about 3.8 and 4.5, respectively. Xylanase synthetized in solid fermentation is a little more thermostable than that from liquid culture and is maximally active at 50° C, compared to 45° C for enzyme from liquid culture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00253605
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  • 7
    Electronic Resource
    Electronic Resource
    β-Glucosidase production by Aspergillus phoenicis in solid state fermentation (1984)
    Springer
    Biotechnology letters 6 (1984), S. 55-60 
    Details
    ISSN: 1573-6776
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary β-glucosidase production was studied in solid-state cultivation by Aspergillus phoenicis on sugar beet pulps. The experiments were carried out in column incubators aerated with humidified air, at 30 °C. Results of physiological studies showed that the production of β-glucosidase from beet pulps in the solid state fermentation required : 70% moisture content, initial pH of about 4, and 107 spores/g substrate. β-glucosidase produced under these conditions could be removed from the solid medium with water, or stored in the form of a dried fermented product, for a direct use in the saccharification reactions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00128230
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  • 8
    Electronic Resource
    Electronic Resource
    β-Glucosidase production in agitated solid fermentation, study of its properties (1984)
    Springer
    Biotechnology letters 6 (1984), S. 451-456 
    Details
    ISSN: 1573-6776
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary β-Glucosidase production by Aspergillus phoenicis was studied in dynamic solid fermentation, on sugar beet pulps. The assays were conducted in agitated tank reactor which allowed for the homogenization of the medium and the regulation of essential parameters: temperature, aeration, pH and humidity. In order to compare some properties of the β-glucosidase produced in both liquid and solid cultures, A. phoenicis was also grown on starch in submerged culture. The enzymes produced in solid and liquid cultures have the same optimum pH of about 4.5. β-Glucosidase synthetized in solid culture is significantly more thermostable than that from liquid culture and is maximally active at 65°C compared to 60°C for enzyme from liquid culture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00129308
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  • 9
    Electronic Resource
    Electronic Resource
    Anaerobic digestion of sugar beet pulps (1984)
    Springer
    Biotechnology letters 6 (1984), S. 379-384 
    Details
    ISSN: 1573-6776
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Anaerobic digestion of sugar beet pulps was studied in a 70 l digestor with sequential feeding, after enzymatic hydrolysis by Trichoderma harzianum cellulases. During the 130 days feeding, 3.6 m3 of biogas were produced with an average content of 58% CH4 from 270 l of hydrolysed pulps at 20 g VS/l. Average yield and production rate were respectively 0.67 m3/kg VS and 0.4 m3/ kg VS and 0.4 m3/m3 of digestor per day.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00138009
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  • 10
    Electronic Resource
    Electronic Resource
    Cellulase production by trichoderma harzianum in static and mixed solid-state fermentation reactors under nonaseptic conditions (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 27 (1985), S. 1385-1388 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Cellulase production from lignocellulosic materials was studied in solid-state cultivation by both static and mixed techniques under nonaseptic conditions. The effects of fermentation conditions, such as moisture content, pH, temperature, and aeration, on cellulase production by Trichoderma harzianum using a mixture of wheat straw (80%) and bran (20%) were investigated. With a moisture content of 74% and a pH of 5.8., 18 IU filter paper activity and 198 IU endoglucanase activity/g initial substrate content were obtained in 66 h. The extension from static column cultivation to stirred tank reactor of 65 L capacity gave similar yields of cellulase.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260270917
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