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  • 1
    Electronic Resource
    Electronic Resource
    Relationship between periodontal probing velocity and gingival inflammation in human subjects (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 20 (1993), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Little is known about the biophysical characteristics of the dentogingival junction in response to the development or resolution of inflammation. The Toronto Automated Periodontal Probe (TAPP) provides an estimate of the integrity of the dentogingival junction by measuring intrapocket probing velocity. The aim of this study was to measure changes of probing velocity in inflamed human periodontium before and after subgingival debridement. 32 subjects exhibiting gingival inflammation were selected; 29 completed the study. Gingival index (GI), plaque index (PLI), bleeding index (BI) and the rate of gingival crevicular fluid flow (CFF) were measured as concomitant variables. The experimental group (N= 16) received scaling, root planing and oral hygiene instruction at baseline. The control group (N=13) received no treatment until after 28 days. Subjects were seen at baseline, day 14, 21 and 28 for measurement of probing velocity and concomitant variables on 6 index teeth. At day 28, the control group was treated and then reassessed 28 days later. The experimental group showed a reduction of 51.6% for mean crevicular fluid flow (p〈0.0001), 79.7% for mean plaque index (p〈0.0001), 58.0% for mean gingival index (p〈0.0001), and 72.0% for mean bleeding index (p〈0.002) at day 28, confirming that inflammation was reduced compared with baseline. No significant changes were observed in the control group until after treatment. The velocity of probing and the formation of a plateau in the velocity profile were recorded. The experimental group demonstrated a significant increase (p〈0.002) in the frequency of plateau formation and a decrease in mean slope between baseline and day 28 (p〈0.02). No significant change was observed in the control until day 56, 28 days after treatment. These data indicate a direct relationship between improved clinical health and increased resistance to probe penetration near the base of the pocket, as reflected by the increased frequency of plateau formation and decreased slope for the terminal segment of the velocity profile curve.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1993.tb01758.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Periodontal immune responses of human lymphocytes in Actinobacillus actinomycetemcomitans-inoculated NOD/SCID mice engrafted with peripheral blood leukocytes of periodontitis patients (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 34 (1999), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1999.tb02222.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Interbacterial aggregation of actinomyces naeslundii and dental plaque streptococci (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 12 (1977), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The ability of human Actinomyces naeslundii strains to aggregate with dental plaque streptococci was found to be strain specific. A. naeslundii strains aggregated strongly more often with specific strains of Streptococcus sanguis and Streptococcus mitis than with Streptococcus mutans strains. The effects of proteolytic enzymes and heat on the interbacterial affinities of A. naeslundii 398A and S. sanguis S, two strains which were found to aggregate strongly, were studied. Enzyme or heat treatment of 398 A, but not S. sanguis S, impaired aggregation. Electron microscopic examination of aggregates of untreated bacteria revealed that the attachment between cells of strains 398 A and S was mediated by short tufts of electron-dense fuzzy components of the cell surfaces. The affinity between cells of A. naeslundii and the streptococci which readily colonize cleaned smooth tooth surfaces may account, in part, for the previously-reported, delayed increase in A. naeslundii proportions among bacteria forming early plaque deposits.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1977.tb00104.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: A comparison of sites in edentulous and partially edentulous patients (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 24 (1989), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The soft tissues adjacent to osseointegrated dental implants (OII) were investigated using clinical, biochemical and microbiological methods. Tooth and implant crevices were compared in 15 partially edentulous patients, examining 28 peri-implant and 19 periodontal sites, and in 6 edentulous patients, examining 13 implant sites. Sites were classified by standard periodontal indices; the crevicular fluid flow determined; crevicular fluid was collected for collagenase assays; and the subgingival bacterial flora was examined and cultured. Differences in clinical parameters were noted in that implants had significantly less keratinized gingiva and deeper probing depths. Crevicular fluid was present in the OII sulcus but the crevicular fluid flow did not differ from that observed from tooth sites either in the partially edentulous or edentulous patients. Tissue collagenase activity and collagenase inhibitor were detected in the implant crevicular fluid and, as in periodontal sites, a strong inverse relationship was found between the levels of active collagenase and collagenase inhibitor. Microbiology included darkfield microscopy, anaerobic culturing for total colony forming unit counts and identification of black pigmented Bacteroides (BPB). Few differences were observed between implants and teeth in partially edentulous patients, indicating that crevices around teeth may act as reservoirs of bacteria which can colonize implant sites. A higher percentage of BPBs and wet spreaders (Capnocytophaga) was noted at partially edentulous implant sites when compared with edentulous implant sites, perhaps reflecting the lower numbers of periodontal pathogens present in edentulous mouths. Overall, the characteristics of implant sulci appear to be similar to periodontal sulci with respect to crevicular fluid flow and microflora.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1989.tb00863.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Some effects of chlorhexidine acetate on the adherence of oral bacteria to dental enamel in vitro (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 12 (1977), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of chlorhexidine acetate on the ability of some oral Streptococcus and Actinomyces strains to attach to bovine enamel were evaluated in an in vitro system. The numbers of bacteria adhering per unit area to enamel blocks immersed in bacterial suspensions were enumerated using an incident light microscope. Pre-incubation of the enamel in whole saliva to form an in vitro pellicle enhanced the adsorption of some strains and reduced the adsorption of others. Pretreatment of uncoated enamel with mouthwash concentrations of chlorhexidine significantly impaired the adsorption of two of the four test strains and enhanced the adsorption of one of the strains. Chlorhexidine pretreatment of saliva-coated enamel enhanced the adherence of all bacterial strains tested. These changes in bacterial adsorption may reflect chlorhexidine-mediated alterations in the properties of pellicle-covered enamel. Pretreatment of the bacterial cells with subinhibitory doses of chlorhexidine acetate or sodium acetate did not significantly reduce the ability of the bacteria to attach to the saliva-coated enamel surface. Together, the data suggest that the reduction in plaque accumulation associated with chlorhexidine mouthrinsing may be independent of a direct inhibition of initial bacterial adsorption to pellicle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1977.tb01523.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Effects of metronidazole on Porphyromonas gingivalis biofilms (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 32 (1997), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Subgingival bacteria exist within a biofilm consisting of cells and extracellular matrix which may afford organisms protection from both antibiotics and components of the host immune system. MIC values for planktonic Porphyromonas gingivalis treated with metronidazole were compared with those obtained for the same strain in biofilms associated with hydroxyapatite (HA) surfaces. The treated biofilms were examined for growth and studied by scanning electron microscopy. A broth assay resulted in an MIC of 0.125 μg/ml for metronidazole against P. gingivalis. P. gingivalis biofilms exhibited growth after treatment with 20μg/ml metronidazole, which was 160 times the MIC for planktonic organisms. The results of this study indicate that biofilm-associated P. gingivalis may be resistant to metronidazole at concentrations which are usually attained by systemic administration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1997.tb00560.x
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