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  • 1
    ISSN: 1432-1238
    Keywords: Key words Inhaled nitric oxide ; ARDS ; Acute respiratory failure ; Hypoxaemia ; Pulmonary hypertension ; Practice guidelines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Although unlicensed, inhaled nitric oxide (NO) therapy is now widely used in the United Kingdom. Our aim was to produce guidelines for the clinical application of inhaled NO in adult intensive care practice, based upon the current level of published information. Methods: The published data regarding the use of inhaled NO in the acute respiratory distress syndrome and right-sided cardiac failure was presented, analysed and discussed. Recommendations based on these data as well as on current experience in the United Kingdom were formulated. Design: An expert group comprising intensive care specialists from within the United Kingdom, representatives from the European Society of Intensive Care Medicine and the Society of Critical Care Medicine and individuals from the Departments of Health and Industry related to the field was assembled. Results: United Kingdom guidelines for the indications, contraindications, dose, delivery, monitoring and scavenging of inhaled NO therapy were produced. Conclusions: The need for additional quality research to establish evidence of efficacy and safety was emphasized. The guidelines are designed to act within the context of current practice and knowledge and should be revised as further data emerge.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 196 (1962), S. 164-165 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Segregations of nickel-rich and copper-rich phases and the formation of metallic copper have previously been reported in the scale present on copper-nickel alloys after dry oxidation in the temperature-range 700-900 C 1,2. At these higher temperatures the formation of the discrete oxide phases ...
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The radiation of divertor heat flux on DIII-D [J. Luxon et al., in Proceedings of the 11th International Conference on Plasma Physics and Controlled Nuclear Fusion (International Atomic Energy Agency, Vienna, 1987), p. 159] is shown to greatly exceed the limits imposed by assumptions of energy transport dominated by electron thermal conduction parallel to the magnetic field. Approximately 90% of the power flowing into the divertor is dissipated through low-Z radiation and plasma recombination. The dissipation is made possible by an extended region of low electron temperature in the divertor. A one-dimensional analysis of the parallel heat flux finds that the electron temperature profile is incompatible with conduction-dominated parallel transport. Plasma flow at up to the ion acoustic speed, produced by upstream ionization, can account for the parallel heat flux. Modeling with the two-dimensional fluid code UEDGE [T. Rognlien, J. L. Milovich, M. E. Rensink, and G. D. Porter, J. Nucl. Mater. 196–198, 347 (1992)] has reproduced many of the observed experimental features. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Recent measurements of the two-dimensional (2-D) spatial profiles of divertor plasma density, temperature, and emissivity in the DIII-D tokamak [J. Luxon et al., in Proceedings of the 11th International Conference on Plasma Physics and Controlled Nuclear Fusion (International Atomic Energy Agency, Vienna, 1987), p. 159] under highly radiating conditions are presented. Data are obtained using a divertor Thomson scattering system and other diagnostics optimized for measuring the high electron densities and low temperatures in these detached divertor plasmas (ne≤1021 m−3, 0.5 eV≤Te). D2 gas injection in the divertor increases the plasma radiation and lowers Te to less than 2 eV in most of the divertor volume. Modeling shows that this temperature is low enough to allow ion–neutral collisions, charge exchange, and volume recombination to play significant roles in reducing the plasma pressure along the magnetic separatrix by a factor of 3–5, consistent with the measurements. Absolutely calibrated vacuum ultraviolet spectroscopy and 2-D images of impurity emission show that carbon radiation near the X-point, and deuterium radiation near the target plates contribute to the reduction in Te. Uniformity of radiated power (Prad) (within a factor of 2) along the outer divertor leg, with peak heat flux on the divertor target reduced fourfold, was obtained. A comparison with 2-D fluid simulations shows good agreement when physical sputtering and an ad hoc chemical sputtering source (0.5%) from the private flux region surface are used. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Data on the discharge behavior, thermal loads, halo currents, and runaway electrons have been obtained in disruptions on the DIII-D tokamak [J. L. Luxon and L. G. Davis, Fusion Technol. 8, 2A 441 (1985)]. These experiments have also evaluated techniques to mitigate the disruptions while minimizing runaway electron production. Experiments injecting cryogenic impurity "killer" pellets of neon and argon and massive amounts of helium gas have successfully reduced these disruption effects. The halo current generation, scaling, and mitigation are understood and are in good agreement with predictions of a semianalytic model. Results from "killer" pellet injection have been used to benchmark theoretical models of the pellet ablation and energy loss. Runaway electrons are often generated by the pellets and new runaway generation mechanisms, modifications of the standard Dreicer process, have been found to explain the runaways. Experiments with the massive helium gas puff have also effectively mitigated disruptions without the formation of runaway electrons that can occur with "killer" pellets. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 4590-4599 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Runaway electrons are calculated to be produced during the rapid plasma cooling resulting from "killer pellet" injection experiments, in general agreement with observations in the DIII-D [J. L. Luxon et al., Plasma Physics and Controlled Nuclear Fusion Research 1986 (International Atomic Energy Agency, Vienna, 1987), Vol. I, p. 159] tokamak. The time-dependent dynamics of the kinetic runaway distributions are obtained with the CQL3D [R. W. Harvey and M. G. McCoy, "The CQL3D Code," in Proceedings of the IAEA Technical Committee Meeting on Numerical Modeling, Montreal, 1992 (International Atomic Energy Agency, Vienna, 1992), p. 489] collisional Fokker–Planck code, including the effect of small and large angle collisions and stochastic magnetic field transport losses. The background density, temperature, and Zeff are evolved according to the KPRAD [D. G. Whyte and T. E. Evans et al., in Proceedings of the 24th European Conference on Controlled Fusion and Plasma Physics, Berchtesgaden, Germany (European Physical Society, Petit-Lancy, 1997), Vol. 21A, p. 1137] deposition and radiation model of pellet–plasma interactions. Three distinct runway mechanisms are apparent: (1) prompt "hot-tail runaways" due to the residual hot electron tail remaining from the pre-cooling phase, (2) "knock-on" runaways produced by large-angle Coulomb collisions on existing high energy electrons, and (3) Dreicer "drizzle" runaway electrons due to diffusion of electrons up to the critical velocity for electron runaway. For electron densities below (approximate)1×1015 cm−3, the hot-tail runaways dominate the early time evolution, and provide the seed population for late time knock-on runaway avalanche. For small enough stochastic magnetic field transport losses, the knock-on production of electrons balances the losses at late times. For losses due to radial magnetic field perturbations in excess of (approximate)0.1% of the background field, i.e., δBr/B≥0.001, the losses prevent late-time electron runaway. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: One mechanism for transport of energy and particles in a plasma is by discrete, intermittent, uncorrelated events, often called avalanches. This paper reports observations and quantitative characterization of avalanche events in a magnetically confined plasma. The observations are primarily of electron temperature fluctuations. Avalanches are identified by their large spatial scale, up to the system size, by self-similar behavior in the frequency spectrum and the autocorrelation function and by propagation. The two-point cross-correlation function allows determination of a characteristic velocity, which typically varies from several hundred meters per second in the outer part of the plasma to zero or even inward near the axis. This can be interpreted as resulting from the prevalence of negative avalanches (i.e., holes) near the axis. The presence of a long-tailed probability distribution is indicated by a Hurst parameter (H) in the range 0.80 to 0.95, which becomes smaller in the outer quarter of the plasma radius. Density fluctuation spectra from the plasma core also show self-similar behavior. Power transport estimates show that about half of the heat flux is carried by the avalanche events under conditions with no magnetohydrodynamic activity. These observations are qualitatively similar to results of modeling calculations based on drift wave turbulence. It is reasonable to infer that avalanches are the macroscopic manifestation of turbulence which inherently has a small spatial scale and, thus, allow a local, gyro-Bohm scaling process to show global Bohm-type behavior. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: The corrosion resistance of stainless steels in the atmosphere. Experiences from Great Britain and the United StatesThe author presents a report on extensive studies concerning the atmospheric corrosion resistance of stainless steels. The data reveal that the stainless types 18/8 and 17/7 chromium/nickel exhibit excellent resistance to urban, industrial and rural atmospheres. In maritime and in polluted industrial atmospheres, however, the molybdenum-containing type (18% Cr, 10% Ni, 2,5% Mo) should be preferred if regular cleaning of the surface meets with difficulties. The differences between British and American experiences can probably be attributed to the comparatively lower atmospheric contamination and the less unfavorable climatic conditions in many parts of Northern America.
    Notes: ES wird über umfangreiche Untersuchungen der atmosphärischen Korrosionsbeständigkeit der nichtrostenden Stähle berichtet. Sie lassen erkennen, daß die nichtrostenden 18/8- und 17/7-Chrom-Nickel-Stähle in städtischen, Industrie- und ländlichen Gebieten ausgezeichnet beständig sind. In Meeresgegend und in verunreinigten Industrieatmosphären ist die molybdänhaltige Qualität (18% Cr, 10% Ni, 2,5% Mo) für Anwendungen zufriedenstellend, wenn eine regelmäßige Reinigung der Oberfläche nur schwer durchführbar ist. Die beobachteten Unterschiede in den amerikanischen und britischen Erfahrungen sind vermutlich in den vergleichsweisen geringeren atmosphärischen Verunreinigungen und den weniger ungünstigen klimatischen Bedingungen in vielen Gegenden Nordamerikas zu suchen.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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