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  • 1
    Electronic Resource
    Electronic Resource
    Mast-cell proliferation in postmenopausal osteoporosis (1983)
    Springer
    Calcified tissue international 35 (1983), S. 29-31 
    Details
    ISSN: 1432-0827
    Keywords: Mast cells ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Because mast cell proliferation has been reported in disorders of abnormal bone remodeling, we quantitated the number of mast cells in undecalcified section of iliac crest bone from 16 untreated women with postmenopausal osteoporosis and contrasted the findings to values from 10 normal women and 12 normal men. The mean number of marrow mast cells was greater in normal women than men (1.17 vs 0.40 cells per mm2,P〈0.05). Compared to the normal women, osteoporotic women had a greater number of mast cells in the marrow (3.38 vs 1.17 cells per mm2,P〈0.01). However, there was no statistically significant correlation between the number of marrow mast cells and either the patient's age or the severity of the bone lesions, as assessed by histomorphometry. Our findings confirm the association between increased numbers of mast cells and postmenopausal osteoporosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405002
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A simple procedure for the rapid histologic diagnosis of metabolic bone disease (1981)
    Springer
    Calcified tissue international 33 (1981), S. 281-283 
    Details
    ISSN: 1432-0827
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02409450
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Ultrastructure of the rat epiphyseal growth plate following chronic ethanol ingestion (1981)
    Springer
    Calcified tissue international 33 (1981), S. 381-384 
    Details
    ISSN: 1432-0827
    Keywords: Alcohol ; Electron microscopy ; Growth plate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary We have previously demonstrated that ethanol has a direct toxic effect on the rat skeleton characterized by decreased trabecular bone volume. In the present study, we examined the ultrastructure of the distal radial epiphyseal growth plates in these same animals. Eight weeks of ethanol administration to 12 male rats results in serum alcohol levels of 140 mg/dl but did not alter the width or light microscopic appearance of the radial growth plate. Quantitative electron microscopy failed to demonstrate morphologic evidence of toxicity in the skeletal cells. We conclude that although ethanol appears to have a direct effect on rat bone characterized by enhanced resorption, toxicity is not attended by ultrastructural changes in the skeletal cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02409460
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Mixed-sclerosing-bone-dystrophy: Report of a case and review of the literature (1981)
    Springer
    Skeletal radiology 6 (1981), S. 95-102 
    Details
    ISSN: 1432-2161
    Keywords: Osteopoikilosis ; Osteopetrosis ; Melorheostosis ; Osteopathia striata ; Osteodystrophy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present clinical, laboratory, radiologic, genetic, and pathologic findings in a 49-year-old man with mixed-sclerosing-bone-dystrophy (MSBD), review the six cases previously reported as “MSBD”, and examine the nosology of this rare bone dysplasia. Our asymptomatic patient showed radiographic changes consistent with osteopoikilosis, osteopathia striata, and melorheostosis and had widespread osteosclerosis of the axial skeleton. Several previous reports of combined osteosclerotic disorders suggest the latter finding represents osteopetrosis, however, histologic examination of our patient's iliac crest excluded that diagnosis. Limited radiographic surveys of his eight children were unremarkable except for isolated bone islands in two sons. Literature review revealed that “MSBD” has actually been used generically to describe the association of a variety of osteosclerotic bone dysplasias when they occur together in a single patient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00347570
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Pseudofractures in the absence of osteomalacia (1982)
    Springer
    Skeletal radiology 8 (1982), S. 17-19 
    Details
    ISSN: 1432-2161
    Keywords: Pseudofractures ; Osteomalacia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The presence of bilateral pseudofractures is generally considered a reliable radiologic diagnostic feature of osteomalacia. We report two women with long-standing bilaterally symmetrical femoral pseudofractures that did not demonstrate the histologic features of osteomalacia upon examination of non-decalcified sections of iliac crest bone. One patient treated empirically for osteomalacia developed evidence of early vitamin D intoxication. We conclude that there is no completely reliable non-invasive diagnostic test for osteomalacia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00361362
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    The magnetic resonance imaging appearance at 1.5 Tesla of cartilaginous tumors involving the epiphysis (1987)
    Springer
    Skeletal radiology 16 (1987), S. 647-651 
    Details
    ISSN: 1432-2161
    Keywords: Magnetic resonance imaging ; Bone neoplasms ; Chondroblastoma ; Clear cell chondrosarcoma ; Iliopsoas bursa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Three cases of lytic, calcified epiphyseal lesions with plain film and computed tomography features suggestive of chondroblastoma were imaged by magnetic resonance imaging. Histopathologic correlation was obtained in each case. Two cases of chondroblastoma showed low signal intensity on both short (TR600/TE20ms) and long (TR2500/TE80ms) spin echo (SE) images. The third case, a clear cell chondrosarcoma, demonstrated increased signal intensity on moderately T2 weighted (TR2500/TE40ms) images. These findings suggest that magnetic resonance imaging may be helpful in distinguishing these lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00357114
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    Paper (German National Licenses)
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