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  • 1
    Electronic Resource
    Electronic Resource
    The relationship between micronutrient depletion and oral health in geriatrics (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 23 (1994), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Changes in the oral microbial flora, some of which are related to mucosal disease, have been delected in the elderly, but the causes are not fully understood. This study has examined the possible role of micronutrient depletions in the reduced colonisation resistance and oral infection exhibited by some elderly subjects. The oral health, oral microbiology and micronutrient status of 37 geriatric patients aged 65–91 years (mean 81 years) were examined. Ten of the patients had no oral mucosal disease. Mucosal pathology in the remainder included erythema (27%). denture stomatitis (24%). angular cheilitis (16%) and atrophic glossitis (41%). Those with mucosal pathology had significantly lower serum iron concentrations (P= 0.02). Serum or plasma concentrations of zinc, copper, selenium, C-reactive protein, transferring, caeruloplasmin, albumin, vitamin A and vitamin E were not significantly different between those with oral disease and those with healthy mouths. Similarly, activity of the selenium-containing enzyme, red cell glutathione peroxidase, did not differ significantly between the two groups. In both groups, plasma selenium concentrations (82%), red cell glutathione peroxidase activity (47%), plasma zinc concentrations (58%) and albumin concentrations (44%) tended to be below the lower limit of the reference interval. The influence of sub-clinical infection on these values is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1994.tb01107.x
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  • 2
    Electronic Resource
    Electronic Resource
    Renal cadmium content in the West of Scotland (1983)
    Springer
    Urological research 11 (1983), S. 285-290 
    Details
    ISSN: 1434-0879
    Keywords: Trace metals ; Cadmium ; Kidney cortex ; Ischaemic heart disease ; Medulla
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The trace element content of kidneys has been documented in very few international centres. Significant differences can be demonstrated between the cortical and medullary levels of calcium, zinc and cadmium. For the West of Scotland the values for the latter are similar to those found in Scandinavia. There are significantly higher cadmium contents in subjects who smoke and who have evidence of ischaemic heart disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256348
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of steroid therapy on serum trace metal levels in sub-fertile males (1984)
    Springer
    Urological research 12 (1984), S. 213-215 
    Details
    ISSN: 1434-0879
    Keywords: Methyl-prednisolone ; Male sub-fertility ; Trace metals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of 96 mg methylprednisolone on trace metals and hormone levels was measured in 13 males with sub-fertility associated with an antibody problem. Over a period of 5 days the serum zinc was significantly reduced (p〈0.05) as was the serum testosterone (p〈0.01). By contrast the luteinising hormone levels rose (p〈0.01) within 3 days of administration of the steroid. The lability of serum zinc to the administration of steroids is further demonstrated by its significant fall (p〈0.01) after 3 days of therapy. These results suggest an adreno-cortical control of zinc in serum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256806
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  • 4
    Electronic Resource
    Electronic Resource
    The effects of treatment on the hypercalciuria of chronic cadmium poisoning (1979)
    Springer
    Urological research 7 (1979), S. 285-289 
    Details
    ISSN: 1434-0879
    Keywords: Cadmium ; Iron ; Bendrofluazide ; Hypercalciuria Hyperzincuria ; Treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cadmium induces a variety of effects on kidney tubules including hypercalciuria. This is accompanied by hyperzincuria. The present work shows that both of these biochemical abnormalities can be corrected but where a state of cadmium-induced-anaemia exists urine zinc and calcium excretion do not follow the expected parallel course in response to iron therapy as they do with bendrofluazide.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256610
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  • 5
    Electronic Resource
    Electronic Resource
    The variability of lead in dusts within the homes of young children (1988)
    Springer
    Environmental geochemistry and health 10 (1988), S. 3-9 
    Details
    ISSN: 1573-2983
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Medicine
    Notes: Abstract The variability of household dust lead concentration and loadings over the period of about a year has been examined in 10 homes. The overall uncertainty on a single sample is ± 65% for lead concentration and ± 81% for lead loading. Redecoration involving electric sanding and/or blow lamp preparation of painted surfaces is the major cause of variation in lead levels. The effect is short lived, levels returning to normal within 2 months of redecoration ending. There is evidence of a seasonal trend for dust loading and lead loading but not for lead concentration. The implications of these findings for blood lead — dust lead exposure studies are considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01675623
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  • 6
    Electronic Resource
    Electronic Resource
    DNA-based presymptomatic diagnosis of Wilson disease (1992)
    Springer
    Journal of inherited metabolic disease 15 (1992), S. 161-170 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Investigation using DNA markers in a family with Wilson disease revealed that an apparently normal child of 10 years of age with non-diagnostic copper biochemistry had the disease. The procedure used linked restriction fragment length polymorphic markers. Demonstration of increased liver copper concentration from a liver biopsy confirmed the diagnosis and the child was started on chelation therapy. Two other asymptomatic siblings were shown, using the same techniques, not to have the disease. Similar analysis was carried out on another family with just one index case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01799625
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  • 7
    Electronic Resource
    Electronic Resource
    Analytical procedures for diagnosis of trace element disorders (1983)
    Springer
    Journal of inherited metabolic disease 6 (1983), S. 5-8 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Trace element levels in tissues show changes in various diseases including inborn errors of metabolism. Such changes may be primary or secondary due to stress or diseases of the liver and gastrointestinal tract. Measurement of trace elements in these cases may be essential both for diagnostic and therapeutic purposes. Trace element measurements can also be useful in other areas of clinical interest including nutrition, toxicity and therapy with inorganic pharmaceutical agents. The available techniques for measuring trace elements in tissues are summarized and the various problems of each are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01811316
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  • 8
    Electronic Resource
    Electronic Resource
    Cadmium effects on the kidney (1983)
    Springer
    Environmental geochemistry and health 5 (1983), S. 88-90 
    Details
    ISSN: 1573-2983
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02084904
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Human albumin as a reference material for trace elements (1988)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 332 (1988), S. 627-629 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary An investigation through interlaboratory comparison using different analytical techniques has been carried out in order to assess the suitability of a plasma protein solution as a source for a trace element reference material in clinical analysis. Reasonable agreement was obtained for a number of elements from the range studied: Al, Ba, Cr, Cu, Fe, Mg, Mn, Mo, Ni, Se, Sr, V and Zn. The techniques used included flame and furnace atomic absorption spectrometry (FAAS and ETA-AAS), furnace atomic emission spectrometry (ETA-AES), inductively coupled plasma atomic emission spectrometry (ICP-AES), inductively coupled plasma mass spectrometry (ICP-MS), and simultaneous multi-element atomic absorption spectrometry (SIMAAC). Results indicated that this plasma protein solution may prove useful as a source for a reference material covering trace element levels outwith the range found in normal human plasma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00472656
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