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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 17 (1989), S. 107-109 
    ISSN: 1434-0879
    Keywords: Prostate cancer ; Metastases ; Cellular fractions ; Epithelium and stroma ; Trace elements
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The concentration of several trace elements (Cd, Zn, Mn, Cr, Pb, Se) as determined both in primary prostatic carcinoma and in metastases of the same patients in unseparated and in separated tissue. In the unseparated tissue a significantly higher amount of all elements studied was found in the primary tumour. Different results were obtained for the concentrations in separated epithelium and stroma as well as in the cellular fractions of metastases and of primary tumour.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-0879
    Keywords: Protatic carcinoma ; Cellular fractions ; Zn and Cd concentration ; Zn and Cd distribution in prostatic slices by laser AAS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution of Zinc (Zn) and Cadmium (Cd) was analyzed in nuclear, mitochondrial and cytosol cellular fractions of prostatic carcinoma of different histological grading, BPH and normal prostate by electrothermal atomic absorption spectrometry (AAS). Distinct differences in Zn and Cd concentration in carcinomatous material in comparison with BPH and normal prostates was found. The highest concentration of Cd and the lowest level of Zn were found in poorly differentiated carcinomas. The results in cellular fractions were compared with investigations on Zn and Cd distribution in prostatic slices by laser AAS.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1434-0879
    Keywords: Prostatic tissues ; Epithelial and stromal fractions ; Zn, Cd, Se concentrations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The concentration of Zn, Cd and Se in unseparated tissues and epithelial and stromal fractions of normal prostate gland, BPH and prostatic carcinomas of different histological grading were determined by flameless AAS. There were distinct differences in the content of Zn, Cd and Se in the epithelial and stromal fractions depending on histology. In all cases the concentration of these elements in the epithelial fractions was higher than in stromal fractions. These differences are discussed.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 17 (1989), S. 41-42 
    ISSN: 1434-0879
    Keywords: Prostatic carcinoma ; Metastasis ; Zn concentration in plasma ; Hormone therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Zinc in serum of both patients with prostatic carcinoma and men without prostatic cancer was analyzed by flame atomic absorption spectrometry (FAAS). No significant differences were found between the group with prostatic carcinoma without metastasis and the group used for comparison. The Zn level in serum of patients with both prostatic carcinoma and metastases was decreased in comparison to the other groups. A decrease in the Zn concentration was also found for men without metastases after orchiectomy and hormone therapy.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 14 (1986), S. 105-108 
    ISSN: 1434-0879
    Keywords: Renal tumours ; Normal renal tissues cellular fractions ; Cd ; Zn ; Cu concentration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution of Cd, Zn and Cu was analyzed in nuclear, mitochondrial and cytosol cellular fractions of renal tumours and normal surrounding kidney tissues by electrothermal atomic absorption spectrometry (AAS). The normal kidney tissues were separated into cortical and medullary parts. A significant decrease of the Cd-levels was found in all cellular fractions from normal kidney to tumour tissues (hypernephroma). The Zn values varied strongly. We noted a slight decrease of Zn levels in renal tumour. The Cu concentration in the nucleus of kidney tumours was significantly increased.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-0879
    Keywords: Prostatic carcinoma ; Zinc and cadmium concentration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Zn and Cd concentrations in tissue of normal prostate gland, BPH and prostatic carcinoma of different histological grades have been determined by atomic absorption spectrometry before therapy. We found a distinct biological anatagonistic effect between Zn and Cd in the human prostate gland. We have seen an increasing amount of Zn in BPH, but a decrease in prostatic cancer. In contrast, we found a continuous increase of cadmium concentration from the normal prostate via BPH through carcinoma.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1434-0879
    Keywords: Prostatic carcinomas ; Cellular tractions ; Zn and Cd concentration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The concentrations of zinc and cadmium in cellular fractions of normal prostate gland, BPH and prostatic carcinomas of different histological grading were determined by electrothermal atomic absorption spectrometry. We found distinct differences in the content of Zn and Cd in the nuclear fractions of malignant tissues in comparison with BPH and normal prostatic tissues. The highest values of Cd were obtained in the nuclear fractions of poorly-differentiated carcinomas. In these samples we also found a low concentration of zinc. In comparison to this the highest Zn-values were found in the nuclear fraction of the BPH.
    Type of Medium: Electronic Resource
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