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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 599 (1980), S. 13-23 
    ISSN: 0005-2736
    Keywords: (Brush border, Chick intestine) ; 1,25-Dihydroxyvitamin D-3 ; Membrane vesicle ; Phosphate transport
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0827
    Keywords: PTH ; Vitamin D ; Pituitary ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Parathyroid gland transplanted rats and hypophysectomized rats were raised from weaning on a diet without vitamin D and low in calcium (0.02%) for 4 weeks. At the end of this period the animals of both experimental groups, when compared to their respective controls (i.e., sham-operated animals for parathyroid-transplanted ones, and hypophysectomized plus bovine growth hormone-supplemented ones for hypophysectomized rats) were characterized by (a) moderate or absent secondary hyperparathyroidism; (b) near normal bone calcium content; and (c) a maintained responsiveness to the calcemic effect of parathyroid extract (PTE). The PTE action is a bone effect that does not require the presence of the kidneys and is not related to changes in serum calcium and/or phosphorus concentrations. These results indicate that when severe hyperparathyroidism is prevented, the sensitivity of bone to the calcemic action of PTE can be maintained in D-deficient calcium-deprived rats. They also suggest that in these animals the main factor leading to resistance to PTH is the state of severe chronic hyperparathyroidism.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 9 (1966), S. 363-372 
    ISSN: 1432-2072
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three cats, conditioned to respond for food in a Skinner-box on an FI schedule of reinforcement, were submitted during 3 months to chronic treatment with daily doses of 0.2 mg/kg morphine hydrochloride. After an initial phase where no effect was observed, the subjects manifested increased responding and a deterioration of timing behaviour. Behavioural tolerance was shown to develop to both effects. Withdrawing the drug resulted in the immediate or progressive suppression of conditioned activity. The findings are discussed by reference to generally accepted conceptions of tolerance and physical dependence.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 39 (1974), S. 309-314 
    ISSN: 1432-2072
    Keywords: Avoidance ; Drug ; Psychotropic ; Rat ; Sidman Schedule ; Sulpiride
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sulpiride, a new psychotropic drug with neuroleptic activity, was administered to rats in a Sidman avoidance schedule. Doses ranging from 1 to 80 mg/kg resulted in the animal receiving fewer shocks. This effect was not correlated with an increase of responding and seemed unrelated to the suppressing action abruptly observed at high doses (i. e. 150 to 200 mg/kg). These results differ from those classicaly obtained with other neuroleptics.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-2072
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Administered to rats trained in an operant conditioning situation on a fixed interval schedule of reinforcement (FI) or on a schedule of differential reinforcement of low rates of responding (DRL), tremorine in doses of 0.5–5 mg/kg intraperitoneally depressed the rate of responding. The rats trained on the DRL-schedule were slightly more resistent to tremorine than the rats trained on the FI-schedule. In both types the effect increased with increasing doses. Administration of atropine (1 mg/kg i. p.) or scopolamine (0.8 mg/kg i. p.) increased the rate of responding. In contrast to scopolamine, atropine did not alter the distribution of responses in time. In a third experiment, the subjects received 5 mg/kg tremorine, plus 1 mg/kg atropine or 0.8 mg/kg scopolamine. The behavioural effects of tremorine, observed in the first experiment, were antagonized by both drugs, the temporal regulation showing a pattern similar to the pattern obtained under the antagonizing drug alone.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Plant growth regulation 16 (1995), S. 55-58 
    ISSN: 1573-5087
    Keywords: barley ; dormancy breakage ; glutathione ; hydrogen peroxide ; seed
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract A striking relation has been shown between the increase of glutathione levels during dormancy breakage of barley seeds and the induction of germination by exogenous glutathione. These findings suggested that glutathione may play a crucial role in dormancy breakage.
    Type of Medium: Electronic Resource
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