ISSN:
0749-1581
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Complete 13C NMR spectral assignments were made for wyosine, 4,9-dihydro-4,6-dimethyl-9-oxo-3-(β-D-ribofuranosyl)imidazo [1,2-a]purine, a hpermodified, fluorescent nucleoside of transfer RNAs, and its isomers methylated at N-5 and at N-1. The influence of the position of N-methylation on the 13C chemical shifts of the tricyclic nucleoside is discussed. In relation to the parent N-unsubstituted compound, the most pronounced changes of chemical shifts appear in wyosime. Chemical shift data for the sugar moiety suggest that the population of the anti conformer in wyosine is higher than in the other tricyclic nucleosides.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260231108
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