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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Mineralium deposita 7 (1972), S. 154-179 
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Résumé L'étude porte sur un amas lenticulaire vertical de magnétite massive et grossièrement grenue, situé dans la province métamorphique de Grenville. Mesurant entre 10 et 40 m de puissance, 100 à 300 m de longueur, et d'une profondeur moyenne d'environ 150 m, le gisement contient 4 millions de tonnes titrant en moyenne 47,8% Fe. Cet amas se distingue des autres dépôts de magnétite du Grenville par sa teneur en fer beaucoup plus élevée et par l'abondance de membres carbonatés dans ses épontes cristallophylliennes. Le minerai est du type eulysite. Sa paragenèse fondamentale consiste en fayalite, magnétite, augite, diopside, grenat, graphite, pyrrhotine et calcite. En se fondant sur les analyses chimiques de 21 échantillons prélevés systématiquement en travers du gisement, ses principaux oligo-éléments sont le Ti (1050 ppm), Mn (1150 ppm), V (50 ppm), Ni (10 ppm) et Cr (25 ppm), auxquels s'ajoute 0,5% S sous forme pyrrhotine et de traces de pyrite et chalcopyrite. Compte tenu des faciès minéralogiques relevés et des caractères chimiques recensés, le gisement de Forsyth semble s'être formé sous une pression de 7 à 8 Kb et à une température de 720 °C ± 20, soit sous des conditions apparentées au début du faciès granulite. A défaut d'une hypothèse rigoureuse pour expliquer ce type particulier de gisement, les auteurs proposent une origine métasédimentaire. Un épais niveau de sidérose riche en impuretés d'argile et de calcaire dolomitique se serait transformé en minerai de magnétite sous l'influence d'un métamorphisme régional très poussé, où le graphite par son caractère réducteur aurait contrôlé les principales réactions chimiques de formation du minerai.
    Notes: Abstract This study bears on a steeply dipping lense of massive coarse-grained magnetite located in the Grenville metamorphic province. The deposit is 10–40 m thick, 100–300 m long and about 150 m deep, with some 4 million tons averaging 47.8% Fe. It differs from other magnetite deposits of the Grenville in being appreciably higher grade and having an abundance of carbonate facies in its highly metamorphosed wallrocks. The ore is a eulysitic type. Its essential paragenesis consists of fayalite, magnetite, augite, diopside, garnet, graphite, pyrrhotite and calcite. On the basis of 21 samples taken systematically across the orebody, its main trace elements appear to be Ti (1050 ppm), Mn (1150 ppm), V (50 ppm), Ni (10 ppm) and Cr (25 ppm), plus 0.5% S in the form of pyrrhotite and traces of pyrite and chalcopyrite. On the basis of chemical-mineralogical relationships, the Forsyth orebody is assumed to have been formed under a pressure of 7–8 Kb and at a temperature of 720 °C ± 20, that is under conditions corresponding to the lower granulite facies. Although this deposit is difficult to explain, the writers view it as having originated from a thick sedimentary layer of siderite containing numerous argillaceous and dolostone impurities, which was later transformed into magnetite ore under the reducing influence of ubiquitous graphite and intense regional metamorphism.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Clinica Chimica Acta 116 (1981), S. 269-275 
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Because latex is a common allergen, the rate of latex sensitization may be high in the general population. A major issue would then be to detennine whether a systematic preoperative screening in the general population should be recommended.Objective The purpose of the study was to evaluate the prevalence of latex sensitization in a sample of the general population and to assess the role of possible risk factors.Methods The subjects were 258 people, aged from 20 to 40 yr, visiting a health care centre for a check-up. The protocol included: a questionnaire (occupation, symptoms of atopy, use of latex goods and possible reactions, history of previous surgery), a skin-prick test, and a CAP RAST to latex. Atopy was evaluated by a skin-prick test to common allergens and a Phadiatop® test.Results Some 6.6% of the study group had either a positive skin test or a positive RAST to latex. These subjects had a four-fold higher prevalence of symptoms when wearing gloves. The rate of latex sensitization was higher by fivefold in subjects with a history of reactions to latex goods and by fourfold in atopic subjects.Conclusions Because the rate of latex sensitization is much higher than the anticipated rate of perioperative reactions due to latex allergy, a systematic preoperative screening for latex allergy should not be recommended for adults.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Epidemiologic and in vitro data have shown that the association of housedust mite (HDM) allergy and snail allergy in the same patients was due to cross-reactivity between HDM and snail allergenic components. However, the cross-reacting allergen(s) have not yet been identified. In vitro reactivity of seven patients' sera to the various extracts and hemolymph of four different Helix snail species was analyzed by IgE detection on immunodots and Western blots. Cross-reactivity between snails and Dermatophagoides pteronyssinus was assessed by immunodot and ELISA inhibition in two patients. Heterologous inhibition of the snail immunodot and ELISA was observed in one serum. Western blotting showed a specific binding on all four snail species extracts: molecular weights of snail allergens ranged from 〈21 to 200 kDa. Marked individual differences were observed in the seven sera under study: most sera demonstrated IgE recognition of multiple bands, illustrating that no single allergen is responsible for cross-reactivity between snail and mite. These results confirm that cross-reactivity exists between snails of the Helix genus and HDM. This cross-reactivity, involving more than a single allergen, may be of clinical significance in atopic patients allergic to D. pteronyssinus. The identity of the cross-reacting allergens remains to be determined. Potential candidates include the thermostable minor allergens of D. pteronyssinus, tropomyosin and hemocyanin. Diseases, Environment.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Although allergen-specific IgE content in serum can be determined immunochemically, little is known about the relationship between this parameter and the strength of the degranulation response upon allergen triggering.Objectives:  Analyse the degranulation capacity of immunochemically defined purified and serum IgE after challenge with anti-IgE or allergen using a rat mast cell line (RBL) transfected with the α-chain of the human high-affinity IgE receptor (FcɛRI).Methods:  Purified IgE specific for 4-hydroxy-3nitrophenylacetyl, purified IgE of unknown specificity, and sera from allergic patients sensitive to Dermatophagoides pteronyssinus and Dactylis glomerata were assessed. Degranulation was measured by a β-hexosaminidase release assay after anti-IgE or allergen-specific challenge.Results:  For purified monoclonal IgE a significant correlation (r = 0.97) was found between the proportion of bound allergen-specific IgE and the strength of the degranulation response. In contrast, no correlation (r = 0.27) was detected after sensitization with serum IgE.Conclusion:  Our studies demonstrate that mast cell activation mediated through IgE from allergic patients is a result of complex relationships that are not only dependent on allergen-specific IgE content but also relate to the capacity to efficiently sensitize and trigger the signalling responses that lead to degranulation.
    Type of Medium: Electronic Resource
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