ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Total Synthesis of Optically Active Steroids, XI. Synthesis of ( - )-De-A-SteroidsOptically active (7aS)-7a-alkyl-5,6,7,7a-tetrahydro-indan-1,5-diones 1 were transformed in to (-)-de-A-steroids 17 by introduction of a ketobutyl-side chain to give 4, conversion to the cyclopenta[f][1]benzopyranes 13, selective hydrogenation, and hydrolysis ring closure reaction.
Notes:
Optisch aktive (7aS)-7a-Alkyl-5,6,7,7a-tetrahydroindan-1,5-dione 1 werden durch Anbau einer Ketobutylseitenkette zu 4, Umwandlung in die Cyclopenta[f][1]benzopyrane 13, selektive Hydrierung und Hydrolyse-Ringschlußreaktion in (-)-Des-A-Steroide 17 übergeführt.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19751080824
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