ZIB

Hits per page

hits 1 - 2 | 2 hits

Sorting

Electronic Resource

EFFECTS OF LONG-TERM ORAL ADMINISTRATION OF GREEN TEA CULTIVATED IN DIFFERENT DISTRICTS IN JAPAN ON BODY WEIGHT, BLOOD LIPID AND GLUCOSE LEVELS ON db/db MICE (2005)

MAEDA, KAYOKO ; HASEGAWA, TAKEO ; MURABAYASHI, KOUSUKE ; [et al.]

Oxford, UK and Malden, USA : Blackwell Science Inc

Journal of food biochemistry 29 (2005), S. 0

add to mindlist on the mindlist

Details

ISSN: 1745-4514

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Process Engineering, Biotechnology, Nutrition Technology

Notes: Previous research using short-term animal experiments has indicated that oral administration of green tea can suppress elevation of blood sugar. However, few data are available on the antihyperglycemia effect of green tea in long-term experiments. In this study, effects of long-term (up to 16 weeks) administration of green tea preparations on body weight, blood sugar and lipid content of db/db and db/+m mice were examined. Preparations were prepared by the same procedure from tea leaves cultivated in different districts in Japan. Significant differences (P 〈 0.05) were observed in the blood parameters and body weight between control and green tea groups of db/db mice. In the case of normal mice, however, no significant difference was observed. In addition, the response to the administration of green tea depended on the source and composition of tea leaves.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1745-4514.2005.00022.x

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

Electronic Resource

Histopathological changes in rabbit uterus carcinoma after transcatheter arterial embolization using cisplatin (1996)

Harima, Y. ; Harima, Keizo ; Hasegawa, Takeo ; [et al.]

Springer

Cancer chemotherapy and pharmacology 38 (1996), S. 317-322

add to mindlist on the mindlist

Details

ISSN: 1432-0843

Keywords: Key words Rabbit ; VX2 uterine cancer ; Embolization ; Cisplatin ; Apoptosis

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The effects of chemoembolization with cisplatin on gynecological malignancy were investigated using rabbit uterine tumors. A group of 20 rabbits were subjected to inoculation of the uterus with 5×107 VX2 carcinoma cells and 4 weeks later were divided into four groups, each consisting of five rabbits: an untreated control group, a group given cisplatin intraarterially (IA), a group subjected to transcatheter arterial embolization (TAE) with Gelfoam particles and a group subjected to transcatheter chemoembolization (TACE) with Gelfoam particles plus 1 mg/kg cisplatin. All groups were examined histologically 2 days after treatment. The untreated control group was further investigated 4 weeks after inoculation. In the untreated control group, the tumor cell nuclei varied in size and were irregular in form, and multiple nuclei and nuclear division were also observed. No necrotic zones were found up to 4 weeks after inoculation. The IA group showed no necrosis, but a few apoptotic cells were scattered throughout the tumor. In the TAE group, necrosis was observed in the center of the tumors, but proliferating cells persisted at the periphery. In the TACE group, necrosis was observed in the central part with many apoptotic cells surrounding the necrotic region in layers. The proliferating cell nuclear antigen (PCNA) index was 95.88% in the untreated control group, 86.6% in the IA group, and 8.62% in the TACE group, indicating a significant reduction in cell proliferation in the TACE group. These findings suggest that TACE results in more effective cytotoxicity than the other two treatments in uterine cancer tumor transplants.