Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Passive dissolution kinetics of titanium in vitro (1993)
    Springer
    Journal of materials science 4 (1993), S. 117-126 
    Details
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: The dissolution of titanium in simulated interstitial electrolyte (SIE), human serum in SIE (serum/SIE) and 8.0 mM ethylenediaminetetraacetic acid (EDTA) in SIE (EDTA/SIE) was measured in vitro. Titanium fibre samples were immersed in these solutions and maintained at 37°C, 10% O2, 5% CO2 and 97±3% relative humidity for 0–5000 h. The concentration of titanium released was quantified using electrothermal atomic absorption spectroscopy. Changes in oxide stoichiometry were determined by Auger electron spectroscopy after processing and immersion in the test solutions. The oxide became nearly stoichiometric TiO2 after immersion, suggesting equilibration of the surface with the solutions. Solution ligands enhanced the magnitude of dissolution, with EDTA〉serum/SIE〉SIE. The dissolution kinetics were empirically fitted by a two-phase logarithmic relationship. The first phase of dissolution (t〈300 h) was dominated by equilibration of the oxide with the solution and the second phase (t〉300 h) by mass diffusion. The dissolution kinetics were similar for the EDTA/SIE and serum/SIE solutions, indicating that the mechanisms of dissolution for each solution may be the same.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00120380
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Prediction of service lifetime and performance of a prosthetic thermoplastic (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 58 (1995), S. 1661-1668 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The service lifetime and performance for a prosthetic and orthotic thermoplastic, SubortholenTM, was measured using correlations between artificial and natural weathering degradation data of (1) the accumulated carbonyl compound concentration at the polymer surface, (2) changes in thickness of the surface reaction zone, and (3) changes in hardness and tensile properties. An empirical, mathematical relationship between artificial and natural weathering exposures is presented. Results show that the hardness degradation is a useful parameter to estimate the different stages in clinical performance of Subortholen. Corroborating hardness, tensile properties, and weathering exposure time, the service lifetime for Subortholen was determined to be 4-6 years. This finding indicates that the correlation between artificial and natural weathering degradation may provide an effective way to calculate the most appropriate time to replace a worn prosthetic or orthotic device before the device passes into a dangerous stage. © 1995 John Wiley & Sons, Inc.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1995.070581001
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Ectopic bone formation via rhBMP-2 delivery from porous bioabsorbable polymer scaffolds (1998)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 42 (1998), S. 491-499 
    Details
    ISSN: 0021-9304
    Keywords: bone regeneration ; osteogenesis ; polymer ; bone morphogenetic protein ; biodegradable ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Drug delivery devices have received considerable interest in the field of tissue engineering due to the advent of proteins that can induce proliferation and differentiation of various cells to form specific tissues and organs, for example, bone morphogenetic protein (BMP-2) for osteogenesis. In this work the delivery of a clinically relevant bioactive factor, recombinant human rhBMP-2, was tested in vivo in a rat ectopic bone induction assay. Contact radiography and radiomorphometry showed significantly more radiopacity (1798 ± 183 mm2 versus 784 ± 570 mm2 radiopaque area/g scaffold) in the BMP scaffolds than controls (p 〈 0.002). De novo woven bone and abundant osteoid formation were confirmed from histological sections while controls contained minimal amounts of tissue. Histomorphometry revealed significantly more bone (124 ± 93 mm2 versus 7 ± 12 mm2) and osteoid (72 ± 43 mm2 versus 20 ± 21 mm2) in the BMP implants (p 〈 0.001). These scaffolds demonstrated the ability to deliver viable rhBMP-2 and to induce bone formation in an ectopic site. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 42, 491-499, 1998.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...