ISSN:
1434-4475
Keywords:
β-Carbolinederivatives
;
Datura stramonium L. var. stramonium
;
1,2,3,4,6,7-Hexahydro-10-hydroxy-azepino-[1,2,3-l, m]-β-carboline-4-one (Homofluorodaturatin)
;
2,3,5,6-Tetrahydro-9-hydroxy-1H-pyrido-[1,2,3,-l, m]-β-carboline-3-one (Fluorodaturatin)
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract In the transverse section of the seeds ofDatura stramonium L. var.stramonium a conspicuous sea-green fluorescence under UV-light (365 nm) can be observed. Thinlayer chromatography of a methanolic extract shows many blue and sea-green fluorescing substances, the main component being a polar, sea-green fluorescing compound. This substance is characteristic for all of the four varieties ofDatura stramonium L., and therefore of taxonomic interest. Isolation was tried by means of different chromatographic techniques. Combination of column chromatography and preparative thinlayer chromatography allowed the isolation of the main product, which was shown to consist of two substances (GF andGFa). Application of chemical and spectroscopic methods established the structure ofGF, named Fluorodaturatin, as 2,3,5,6-Tetrahydro-9-hydroxy-1H-pyrido-[1,2,3-l, m]-β-carboline-3-one. The second substanceGFa, called Homofluorodaturatin, was identified as analogue ofGF and the structure could be determined as 1,2,3,4,6,7-Hexahydro-10-hydroxyazepino-[1,2,3-l, m]-β-carboline-4-one.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00900008
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