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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 159 (1980), S. 71-80 
    ISSN: 1432-0568
    Keywords: Synaptic ribbons ; Pineal gland ; Light deprivation ; Golden hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Synaptic ribbons were studied in the pineal system of the golden hamster (Mesocricetus auratus) under various conditions of light deprivation. Five weeks of constant darkness led to an increase in the number of synaptic ribbons in both the superficial and the deep part of the organ, and after ten weeks a further increase was observed. In animals returned to normal lighting conditions for one week, after ten weeks of constant darkness, a marked decrease was recorded and five weeks after termination of light deprivation the number of synaptic ribbons was slightly below the normal level. In addition to long rod-shaped ribbons, atypically formed aggregations of electron dense material appear in the synaptic ribbon fields of light-deprived hamsters; dense core vesicles were observed in the vicinity of the ribbons with particular frequency. It is assumed that the topographical relationship between dense core vesicles and synaptic ribbons is of functional significance in relation to the regulation of pineal antigonadal activity.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 153 (1978), S. 295-304 
    ISSN: 1432-0568
    Keywords: Supraependymal cells ; Thirds ventricle ; Deep pineal ; Golden Hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The wall of the third ventricle in the pineal reces of the golden hamster (Mesocricetus auratus) has been investigated by light and electron microscopy. Deep in the pineal recess, where the ependymal lining is thin and non-ciliated, clusters of pinealocytes protrude into the ventricular lumen. They force the ependyma apart so that their surface is directly exposed to the CSF, while basal processes extend towards the hypependymal pineal tissue. It is assumed that these cells may secrete melatonin into the CSF which is known to contain varying amounts of this hormone.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 162 (1981), S. 313-323 
    ISSN: 1432-0568
    Keywords: Synaptic ribbons ; Pineal gland ; Vole (Microtus agrestis)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the pineal system of the vole (Microtus agrestis) both the superficial and the deep pineal exhibit a high percentage of synaptic ribbons lying in intimate contact with the cell membrane of the pinealocytes. At the sites of contact, densities resembling the presynaptic dense projections of synapses are arranged between the ribbons and the cell membrane. Opposite the sites of contact various elements were found. The quantitative estimation revealed that in the superficial pineal about 40% and in the deep pineal about 60% of the membrane-contacting ribbons are located opposite glial cells: in both organ parts about 18% of the membrane-contacting ribbons were found opposite adjacent pinealocytes. The location of ribbons at the perivascular space was almost exclusively found in the superficial pineal, while the cerebrospinal fluid-contacting area in the deep pineal exhibited ribbons in intimate contact with the lumen of the third ventricle. The heterogeneity of the topographical relationships would seem to indicate a diffuse functional effect of the synaptic ribbons in the mammalian pineal gland.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 169 (1984), S. 91-96 
    ISSN: 1432-0568
    Keywords: Third ventricle ; Pineal gland ; CSF-contacting cells ; Season ; Golden hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cerebrospinal fluid-contacting area in the pineal recess of the golden hamster (Mesocricetus auratus) has been investigated light and electron microscopically. The results reveal that in this area the ventricular surface is composed of glial cell processes and protruding pinealocytes. The relative extent of these two components varies considerably and seems to be related to the season of the year: Morphometric analysis shows that in June, the mean size of the total cerebrospinal fluid-contacting area and, in addition, the relative extent of the area occupied by protruding pinealocytes is significantly larger than in November. The physiological significance of this finding remains to be determined.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The two avian benzodiazepine binding proteins offer an opportunity for further studies concerning their regional variation and their phylo-and ontogenetic development. Accordingly, regional variation of the benzodiazepine binding proteins is investigated further in two reptiles and chicken using photoaffinity labeling with [3H]flunitrazepam followed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and fluorography. Whereas regional heterogeneity is pronounced in chicken, it is not readily apparent in the two reptiles. The ontogeny of the benzodiazepine binding proteins in chicken forebrain and cerebellum is remarkably similar to that previously reported in rodents. The results are discussed in light of the possible existence of the γ-aminobutyric acid/benzodiazepine receptor as an isoreceptor complex.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 199 (1979), S. 473-482 
    ISSN: 1432-0878
    Keywords: Synaptic ribbons ; Pineal gland ; Postnatal development ; Golden hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Synaptic ribbons, functionally enigmatic structures of mammalian pinealocytes, were studied during the postnatal development of the pineal gland in the golden hamster (Mesocricetus auratus). On day 4 post partum, synaptic ribbons appear in cells that have already started to differentiate into pinealocytes. Between days 4 and 9, an increase in the number of synaptic ribbons occurs, concomitant with the continuing differentiation of the pineal tissue. Between days 9 and 16, when differentiation of this tissue is almost completed, the number of synaptic ribbons decreases and approaches that characteristic of the adult pineal gland. During development, the synaptic ribbons increase in length, and dense core vesicles are frequently found in the vicinity of these structures. It is assumed that a functional relationship exists between dense core vesicles and the synaptic ribbons, which are considered to be engaged in a certain form of secretory activity of the mammalian pineal gland.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0878
    Keywords: Supraependymal cells ; Third ventricle ; Pineal gland ; Mammals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ventricular lining in the pineal recess of the vole (Microtus agrestis), guinea pig (Cavia cobaya) and Rhesus monkey (Macaca mulatta) was investigated light and electron microscopically. Deep in the pineal recess of all three species the ependymal lining exhibits interruptions. A varying proportion of pinealocytes penetrates through this ependymal area, so that the surface of the protruding cells is directly exposed to the cerebrospinal fluid (CSF). At their base, these cells are anchored in the hypependymal tissue by means of processes. It is conjectured that these pinealocytes are engaged in secreting pineal substances into the CSF, as various physiological findings appear to indicate.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 222 (1982), S. 177-185 
    ISSN: 1432-0878
    Keywords: Supraependymal cells ; Third ventricle ; Pineal gland ; Mongolian gerbil
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The pineal system of the Mongolian gerbil (Meriones unguiculatus) was investigated by light and electron microscopy, special attention being paid to the sites of contact with the ventricular system. The results reveal that the pineal system of this species has a specific topographical relationship to the suprapineal recess of the third ventricle. The dorsal side of the proximal part of the pineal system forms the floor and the caudal wall of this recess. Here, a consistent and relatively large area lacks an ependymal lining, enabling pinealocytes to come into direct contact with the cerebrospinal fluid (CSF). This area is assumed to be the morphological correlate of a close functional interrelationship between the pineal tissue and the CSF.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0878
    Keywords: Photoperiods ; Pituitary gland, pars tuberalis ; Ultrastructure ; Phodopus sungorus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Conspicuous cytological differences are found between specific secretory cells of the hypophysial pars tuberalis of Djungarian hamsters exposed to long and short photoperiods. The cells differ with respect to the shapes of perikarya and nuclei and show diverse amounts of secretory granules, lysosome-like bodies and glycogen.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0878
    Keywords: Capillary permeability ; Lanthanum tracer ; Pineal gland ; Rodents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Capillaries in the pineal gland of the rat (Rattus norvegicus), gerbil (Meriones unguiculatus) and golden hamster (Mesocricetus auratus) were investigated by means of electron-microscopical tracer studies using lanthanum. The tracer was administered together with the fixative solution by perfusion via the left cardiac ventricle. In the rat, endothelial junctions of fenestrated capillaries are permeable to lanthanum. In the gerbil the tracer does not leave the capillaries, which are of the non-fenestrated type throughout the organ. In the golden hamster the two portions of the pineal system have different types of capillaries. While in the superficial pineal fenestrated capillaries permeable to lanthanum predominate, the deep pineal possesses capillaries that are, without exception, devoid of fenestrations and impermeable to the tracer. It is suggested that differences in the structure of the capillaries are related to differences in the extent of a specialized contact of the pineal gland to the third ventricle.
    Type of Medium: Electronic Resource
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