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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 15 (1993), S. 119-123 
    ISSN: 1279-8517
    Keywords: Cancer cell coexistence ; Colliding tumor ; Immunohistochemical double staining ; Lymph system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs décrivent la coexistence dans un même noeud lymphatique de cellules tumorales provenant de deux cancers différents. L'observation est celle d'un sujet masculin de 83 ans décédé d'une lymphangite carcinomateuse pulmonaire cinq mois après gastrectomie pour cancer. L'autopsie montra l'existence de métastases lymphonodales d'un cancer prostatique. Histologiquement, les métastases du cancer prostatique présentaient un aspect cribriforme tandis que les cellules d'origine gastrique dessinaient des formations papillaires et tubulaires. En immunohistochimie les premières se révélaient positives à l'antigène prostatique spécifique (PSA), et les autres à l'antigène carcino-embryonnaire (ACE). Cinquante et un noeuds rétropéritonéaux et pelviens furent examinés : la coexistence des deux types de cellules métastatiques fut observée dans deux noeuds. Les deux types se retrouvaient associés au niveau du hile, fait confirmé par les réactions immunohistochimiques. Les deux noeuds intéressés étaient situés dans la région préaortique et latéro-aortiques gauche et appartenaient au groupe des noeuds proximaux qui collectent à la fois la lymphe des organes pelviens et celle des organes digestifs intra-abdominaux.
    Notes: Summary The coexistence of two differently originating cancer cells within the same lymph node is reported. An 83-year-old male patient died from severe carcinomatous lymphangitis of the lungs five months after gastrectomy for gastric cancer. At autopsy, prostatic cancer metastasis to lymph node was found. Histologically, the prostatic carcinoma cells had a cribriform pattern and the gastric cells showed papillary and tubular features. Immunohistochemically, the former was immunoreactive to prostate specific antigen (PSA) and the latter was stained positively for carcinoembryonic antigen (CEA). Fifty-one of the retroperitoneal and intrapelvic lymph nodes were histologically examined; the coexistence of both types of cancer cells was found in two lymph nodes. Both types were adjoined at the hilum, as was also confirmed by an immunohistochemical double staining technique. These two lymph nodes were located in the pre-aortic and left lateral aortic areas, and they belonged to the terminal lymph node group of both the intra-pelvic and intra-abdominal intestinal organs.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0047-6374
    Keywords: Aging ; B-16 melanoma ; Metastasis ; Mouse ; Prabiosis
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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