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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 348 (1994), S. 606-614 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Using an automated on-line phase extraction device, followed by HPLC, various pesticides groups can be separated and quantified chromatographically in a single run. By using a diode-array detector capable of automatically identifying components and determining their homogeneity by utilizing multiple, non subjective spectral comparison techniques, correct results can be obtained. For peaks that co-elute due to inadequate resolution, Multi Component Analysis (MCA) provides quantitative accuracy with a determination limit as low as 0.010 μg/L with few exceptions.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 12 (1979), S. 368-370 
    ISSN: 1612-1112
    Keywords: Automation in HPLC ; Ion-pair partion chromatography ; Pre-column derivatisation ; Alkaloids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary An automated pre-column derivatisation system is presented. As an example of its application we have chosen ion-pair partition chromatography. Ion-pairs of a mixture of some alkaloids (apoatropine, hyoscyamine, scopolamine and ergotamine) were formed with picric acid in an aqueous phase, extracted into chloroform and injectedin-situ onto a silica gel column for separation within 15 minutes. This paper shows the possibility of making an automated pre-column derivatisation system with a relative standard deviation of less than 3% per injection (n=6). The linearity check was made for hyoscyamine and ergotamine solutions in the concentration range of 80 to 200 ng respectively 240 to 720 ng per injection and found to be linear. The information obtained is of general validity and could generate more studies in this area.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 12 (1979), S. 405-407 
    ISSN: 1612-1112
    Keywords: Automatisation in HPLC ; Combination of HPLC with CFA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary An automatic device combining high-performance liquid chromatography and continuous flow analysis (HPLC/CFA) has been developed for the individual analysis of pharmaceutical tablets. With this fully automated system up to 60 tablets can be analysed in sequence. Between each sequence of tablets up to 3 reference solutions can also be automatically analysed. The reproducibility is better than 2% for all compounds, by repetitive injections of a mixture of drugs.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 2 (1979), S. 154-154 
    ISSN: 0935-6304
    Keywords: Liquid Chromatography, HPLC, ion-exchange ; Specific detection of alkaloids ; Post-column derivatization - fluorimetric ion-pair technique ; Fluorimetric determination of tropane alkaloids in pharmaceuticals ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 213-214 
    ISSN: 0935-6304
    Keywords: Liquid chromatography ; Specific detections ; Post-column derivatization ; Fluorometric ion-pair technique ; Fluorometric determination of pharmaceutical amines ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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