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  • 1
    Electronic Resource
    Electronic Resource
    Correction-A Generalized Equation for Diffusion in Liquids (1964)
    s.l. : American Chemical Society
    Journal of chemical & engineering data 9 (1964), S. 157-157 
    Details
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/je60020a602
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A Generalized Equation for Diffusion in Liquids. (1963)
    s.l. : American Chemical Society
    Journal of chemical & engineering data 8 (1963), S. 198-201 
    Details
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/je60017a017
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Thermal Conductivities of Organic Liquids-A New Correlation. (1966)
    s.l. : American Chemical Society
    Journal of chemical & engineering data 11 (1966), S. 73-76 
    Details
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/je60028a021
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Corrections-A Generalized Equation for Diffusion in Liquids (1964)
    s.l. : American Chemical Society
    Journal of chemical & engineering data 9 (1964), S. 157-157 
    Details
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/je60020a052
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Use of Acid-Dye Technique in the Analysis of Natural Products. III. Spectrophotometric Microdetermination of Khellin and Bergapten (1979)
    s.l. : American Chemical Society
    Journal of natural products 42 (1979), S. 366-373 
    Details
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/np50004a003
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    A new minimally invasive technique to show nerve ischaemia in diabetic neuropathy (1999)
    Springer
    Diabetologia 42 (1999), S. 737-742 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Diabetic neuropathy ; spectrophotometry ; sural nerve ; nerve blood flow ; oxygen saturation.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aims/hypothesis. Experimental studies have shown that abnormalities of nerve microcirculation are important factors in the pathogenesis of diabetic neuropathy but there have been few clinical studies. We have applied microlightguide spectrophotometry to measure intravascular oxygen saturation (HbO2%) and blood flow in human sural nerve. Methods. We studied ten patients with mild-moderate sensory motor diabetic neuropathy, nine patients without neuropathy and nine control subjects. We took 300 measurements of oxygen saturation under direct visual control through a 1.9 mm rigid endoscope over three regions of the nerve. Spectrophotometric measurements of nerve fluorescence were taken after an intravenous injection of sodium fluorescein and the rate of increase in nerve fluorescence (rise time) was used as an indicator of nerve blood flow. Results. Nerve oxygen saturation was reduced in patients with neuropathy compared with control subjects (67.1 ± 2.2 % vs 76.7 ± 2.1 %, p = 0.006). Fluorescein rise time was prolonged in patients with neuropathy compared with the control group (48.5 ± 7.0 s vs 14.0 ± 3.1 s, p = 0.001) suggesting impaired nerve blood flow. There was a correlation between rise time, nerve oxygen saturation, glycaemic control and sural nerve sensory conduction velocity (p 〈 0.01). Conclusion/interpretation. The combination of microlight-guide spectrophotometry and micro-endoscopy provides a valuable minimally invasive technique for clinical investigation of nerve microcirculation. We have shown reduced nerve oxygenation and impaired blood flow in diabetic neuropathy and these findings strongly support a central role of microvascular disease in the pathogenesis of diabetic neuropathy. [Diabetologia (1999) 42: 737–742]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250051222
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  • 7
    Electronic Resource
    Electronic Resource
    Immune responses of mice after conjunctival exposure toChlamydia trachomatis serovar A (1988)
    Springer
    Medical microbiology and immunology 177 (1988), S. 349-356 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract CBA/J mice were inoculated in the lower conjunctival sac with live elementary bodies (EBs) ofChlamydia trachomatis serovar A. Recovery of chlamydia after exposure was done by culture of conjunctival swabs and draining lymph node (D-LN) cells in McCoy cells grown on coverslips in isolation vials. Cellular immune responsiveness was measured by lymphocyte proliferation assay of D-LN cells stimulated with irradiated EBs of serovars A, C, or L2. Humoral immunity was measured by enzyme-linked immunosorbant assay (ELISA) and immunoblot analysis. Chlamydia were consistently isolated from the conjunctiva and from the D-LN at 1 and 7 days after exposure respectively. Intermittent isolations were obtained from the conjunctiva up to day 4 and from the D-LN up to day 14 after a single exposure. Serovar A EB-stimulated lymphocyte proliferation was strong by 1 week after conjunctival exposure, but by 4 and 5 weeks, blastogenic responsiveness was very low. This lack of responsiveness may reflect a state of immunosuppression. Responses to serovars C and L2 EBs were consistantly lower than to serovar A EBs. Serum IgG antichlamydia antibodies were not detected by ELISA until 2 weeks after exposure, peaked by 4–5 weeks, and decreased between 5 and 7 weeks after exposure. The IgM response was minimal at all times tested. There was, however, a modest increase in IgM antibodies at 3 and 5–7 weeks after exposure. Immunoblot analysis showed reactivity of mouse serum antibodies with polypeptide bands of 30, 41, and 52 kD at 3 and 4 weeks post exposure and predominantly with the 52 kD moiety at 5 weeks post exposure. These studies along with the effect of multiple exposures on the immune response may provide a model system which will assist in the understanding of the immune responses and immunomodulation that occur in trachoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02389907
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  • 8
    Electronic Resource
    Electronic Resource
    DNA microarray technology and its applications in dermatology (2004)
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Experimental dermatology 13 (2004), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract:  The use of DNA microarray technology in biomedical research has dramatically increased during the past years. In the present report, we provide an overview on the basic DNA microarray technology and biostatistical methods for gene expression analysis. A focus is then put on its applications in dermatological research. In recent years, a series of gene expression studies have been performed for various dermatological diseases, such as malignant melanoma, psoriasis and lupus erythematosus. These analyses have identified interesting target genes as well as putative disease susceptibility loci. However, further functional studies will be needed for a more complete understanding of the pathogenesis of these diseases. This may be performed by means of the recently developed RNA interference technology. Besides its role in large-scale gene expression studies, DNA microarray technology has proved to be a valuable tool for genomic screens of genetic alterations, e.g. single nucleotide polymorphisms. These play a role in tumour development and progression, and also function as genetic markers for disease susceptibility. Taken together, DNA microarray technology opens enormous perspectives for dermatologists. It may help us understand the complex pathogenesis of a wide variety of dermatologic diseases and identify their genetic background.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0906-6705.2004.00243.x
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  • 9
    Electronic Resource
    Electronic Resource
    Thalassæmia in an English and in a German Family (1961)
    [s.l.] : Nature Publishing Group
    Nature 191 (1961), S. 822-822 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Recently, we have been studying the frequency of the carrier form of this abnormality (thalasssemia minor) in subjects of Greek, Egyptian, Syrian, Armenian, Italian, Ethiopian and Sudanese (Northern, 'Arab' and Southern, 'Negro') origin, using, as an absolute criterion, the presence of an increased ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/191822a0
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  • 10
    Electronic Resource
    Electronic Resource
    Effect of oxidant exposure on monkey intestinal brush-border membrane
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 1147 (1993), S. 169-176 
    Details
    ISSN: 0005-2736
    Keywords: (Intestine) ; Brush-border membrane ; Fluidity ; Lipid peroxidation ; Transport
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(93)90001-G
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