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  • 1
    Electronic Resource
    Electronic Resource
    Reply to “Clarifying AIDS vaccine trial guidelines” (1998)
    [s.l.] : Nature America Inc.
    Nature medicine 4 (1998), S. 1091-1091 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Ivinson replies—I am grateful for Jon Cohen's clarification. It is indeed an important issue and as such clarity is important. Cohen agrees that a consensus was reached but disagrees with respect to what that consensus applied to. Ruth Macklin has told Nature Medicine that despite the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2763
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  • 2
    Electronic Resource
    Electronic Resource
    Hard-won consensus on AIDS vaccine trial guidelines (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 874-874 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Following an intense two-day session at the World Health Organization's Geneva headquarters on June 25–26th, an ad hoc group convened by the Joint United Nations Programme on HIV/AIDS (UNAIDS) reached an eleventh hour consensus on guidelines covering ethical considerations in anti-HIV vaccine ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nm0898-874a
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Therapies that make sense (1993)
    [s.l.] : Nature Publishing Group
    Nature genetics 4 (1993), S. 215-217 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The field of gene therapy has matured to the extent that countless therapeutic protocols are being advanced through animal testing into first phase clinical trials and beyond1. A realisation that no single approach will suffice but rather each disease will necessitate the design of a unique ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng0793-215
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The death of just another AIDS orphan? (2001)
    [s.l.] : Nature Publishing Group
    Nature medicine 7 (2001), S. 755-755 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] AIDS was first reported 20 years ago last month in the United States Morbidity and Mortality Weekly Report. Since the start of the epidemic, the disease has cost the lives of nearly 22 million adults and children—12-year-old South African AIDS activist Nkosi Johnson being just one of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/89836
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Inhibition and over-reaction (1993)
    [s.l.] : Nature Publishing Group
    Nature 366 (1993), S. 488-488 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WHEN startled, most people jump, a reflex which is presumably a primitive defence mechanism. It is, perhaps, surprising then that people in whom this reaction is exaggerated (as in patients with startle disease, otherwise known as hyperexplexia) are probably more at risk than those lacking the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/366488a0
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  • 6
    Electronic Resource
    Electronic Resource
    Huntington's is still holding out (1993)
    [s.l.] : Nature Publishing Group
    Nature 366 (1993), S. 90-90 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] HUNTINGTON'S disease is a disorder to be reckoned with. The causative gene managed to remain hidden for a full ten years of intensive international gene searching after linkage was established, and now the fear that finding it might have been the easy bit seems to be being borne out. As Francis ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/366090a0
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  • 7
    Electronic Resource
    Electronic Resource
    Righting an inherited wrong (1994)
    [s.l.] : Nature Publishing Group
    Nature 368 (1994), S. 665-665 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A gene-therapy trial meets with success, and genetic mapping becomes an increasingly sophisticated but nonetheless accessible ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/368665a0
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  • 8
    Electronic Resource
    Electronic Resource
    TAP1 and TAP2 polymorphism in coeliac disease (1993)
    Springer
    Immunogenetics 38 (1993), S. 345-350 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Coeliac disease is strongly associated with HLA-DQ2, but it is possible that additional major histocompatibility complex genes also confer disease susceptibility. Encoded close to HLA-DQ are two genes, TAP1 and TAP2, whose products are believed to transport antigenic peptides from the cytoplasm into the endoplasmic reticulum. Comparison of 81 coeliac disease patients with caucasoid controls revealed an increased frequency of the alleles TAP1A and TAP2A in the patient population. However, no significant difference was found when patients were compared with HLA-DR and -DQ matched controls, indicating linkage disequilibrium between TAP1A, TAP2A, and HLA-DQ2. The TAP gene products do not have a major influence on susceptibility or resistance to coeliac disease in a Northern European Caucasoid population.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210476
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    Paper (German National Licenses)
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