Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Serumkonzentrationen der Immunglobuline bei Kindern im Verlaufe der Cöliakie unter besonderer Berücksichtigung von IgE (1971)
    Springer
    Journal of molecular medicine 49 (1971), S. 256-260 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 49 Kindern mit typischen klinischen Zeichen der Cöliakie wurden die Serumkonzentrationen an IgG, IgA, IgM, IgD und IgE bestimmt. Eine signifikante Erhöhung der Immunglobuline über den 2-Sigma-Bereich der Norm hinaus war bei 28 (57,1%) Patienten für IgA und bei 32 (65,3%) Patienten für IgM zu beobachten. Erhöhte γG-Spiegel wurden bei 11 (22,4%) und erhöhte γD-Spiegel bei 7 (14,3%) der Kinder mit Cöliakie gefunden. Die Mehrzahl der untersuchten Patienten, d.h. 38 von 49 Kindern (77,6%) hatten normale γE-Spiegel. Bei einem der Kinder mit erhöhten γE-Werten bestand zusätzlich zur Cöliakie ein Befall mit intestinalen Parasiten. Ein Anhalt dafür, daß bei der Cöliakie primär allergische Reaktionen vom Sofort-Typ eine Rolle spielen, liegt nach vorliegenden Untersuchungen somit nicht vor. Es ist allerdings möglich, daß sekundär bei einem geringeren Prozentsatz der erkrankten Kinder auch allergische Reaktionen vom Sofort-Typ das klinische Bild mitbeeinflussen können.
    Notes: Summary The serum concentrations of IgG, IgA, IgM, IgD and IgE were determined in 49 children with typical clinical evidence of celiac disease. A significant elevation beyond the normal 2 Sigma limit was observed in 28 patients (57,1%) for IgA, and in 32 patients (65,3%) for IgM, respectively. Elevated γG levels were found in 11 cases (22.4%) and elevated γD levels in 7 children (14,3%) with celiac disease. The majority of patients, namely 38 of 49 children (77.6%) had normal IgE levels. One child with elevated γE had intestinal parasites along with the celiac disease. This investigation does not indicate that immediate type allergic reactions play a primary role in celiac disease. It is possible, however, that the clinical symptoms in a smaller percentage of children with celiac disease may be secondarily influenced by immediate type allergic reactions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01485426
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Interaction of Polyclonal Human IgE with Protein-A from Staphylococcus aureus (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Immunological reviews 41 (1978), S. 0 
    Details
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-065X.1978.tb01467.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Are Increased IgE-Levels a Signal of an Acute Graft-Versus-Host Reaction? (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Immunological reviews 71 (1983), S. 0 
    Details
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-065X.1983.tb01068.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The effect of orally administered sodium cromoglycate on symptoms of food allergy (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 7 (1977), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A comparison was made between the effects of sodium cromoglycate (SCG) and placebo on symptoms of food allergy in twenty children. Both the clinician's and patient's preferences and the clinician's evaluation of the specific response to challenge showed a significant benefit from SCG. A striking effect on skin symptoms was seen in some children and the recorded mean score for skin symptoms was lower after 2 weeks’ treatment with sodium cromoglycate. However, the differences detected from the mean symptom scores were not statistically significant. Neither were there any significant changes in the IgE, IgG, IgA and IgM food allergen antibody levels related to the treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1977.tb01431.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Comparison of IgE values as determined by different solid phase radioimmunoassay methods (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 6 (1976), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Accurate measurement of low IgE concentrations is technically difficult. In this paper results obtained by a direct sandwich and three inhibition methods of radioimmunoassays are compared. For values above 50 U/ml good correlation was obtained with all methods. Below 50 U/ml, however, the inhibition methods tended to yield falsely high values. For very low concentrations, 1–10 U/ml the best correlation was obtained between the direct sandwich test (PRIST*) and the inhibition test using a correction factor to allow for the non-specific effect of serum.The four methods were used to quantify IgE in cord serum samples from healthy individuals. The mean value obtained by PRIST was 0.4 U/ml and by the inhibition test, using a correction factor, 0.6 U/ml respectively. Because of its greater simplicity the direct sandwich test is recommended.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1976.tb01417.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Allergenic characterization of Acarus siro and Tyrophagus putrescentiae and their crossreactivity with Lepidoglyphus destructor and Dermatophagoides pteronyssinus (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 24 (1994), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Allergenic components in extracts of Acarus siro and Tyrophagus putrescentiae were identified by sodium dodecyl sulphate-polyacrylamide (SDS-PAGE) and immuno-blotting. Five and four allergenic components, respectively, were visualized with sera from farmers sensitized to storage mites. The highest frequency of IgE-binding was to a 15kDa component of A. siro (7/9 sera) and a 16kDa component of T. putrescentiae (23/29 sera). The allergenic crossreactivity of A. siro and T. putrescentiae with Lepidoglyphus destructor and Dermatophagoides pteronyssinus was studied with an immunoblotting inhibition technique. Crossreactivity between D. pteronyssinus on the one hand and A. siro and T. putrescentiae on the other, was shown, as the IgE reactivity to a 25 kDa component of D. ptertonyssinus was inhibited to the same degree by extracts of A. siro, T. putrescentiae and D. pteronyssinus. However, D. pteronyssinus was a poor inhibitor of the allergenic components of A. siro and T. putrescentiae. Strong cross-reactivity was also shown between L. destructor and the allergenic components of A. siro and T. putrescentiae, while the latter mite species only to a very low degree inhibited the allergenic components of L. destructor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1994.tb00985.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Lability in complement receptor mobilization of granulocytes in patients with bronchial hyperreactivity (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 22 (1992), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The recruitment of activated granulocytes to bronchial mucosa seems to be involved in the prolonged inflammatory response observed in asthma and probably associated with bronchial hyperresponsiveness. We studied the patients with bronchial hyperresponsiveness with respect to the expression of complement receptor type 1 (CR1), its variability and readiness to become mobilized on peripheral granulocytes from patients with bronchial hyperresponsiveness. CR1 expression and its hourly variation was significantly (P 〈 0.02, P 〈 0.01 respectively) higher in the patient group compared with the control group. In addition the ability to mobilize CR1 spontaneously at +37°C correlated to the variation of CR1 expression that occurred during a 4 hr period. These findings indicate that granulocytes from patients with bronchial hyperresponsiveness have a higher degree of variation in CR1 expression that correlates to their ability to mobilize CR1 and may reflect a more pronounced lability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1992.tb02828.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Effects of maternal diet during late pregnancy and lactation on the development of IgE and egg- and milk-specific IgE and IgG antibodies in infants (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 21 (1991), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The IgE levels and food-allergen-specific IgE- and IgG-antibodies (Ab) to oval bumin (OA), ovomucoid (OVO) and β-Mactoglobulin (BLG) were determined up to 18 months of age in 163 infants born to women who were atopic. A high (HIGH group) or a low (REDUCED group) intake of hen's egg and cow's milk by the mother during the third trimester gave no significant differences in the concentrations of IgE or in IgE-Ab (OVO, BLG) and IgG-Ab (OA, OVO, BLG). Similarly, a prolongation of the abstention diet to the early lactation period did not influence the immune response. The IgG-Ab levels to all three food allergens decreased significantly (P 〈 0.001) in both study groups between birth and 2 months of age, but then increased significantly (P 〈 0.001) between 6 and 18 months of age. The presence in serum of IgE-Ab to OVO (≥ 0.15 PRU/ml) was associated with significantly higher IgG-Ab levels to OVO at 6 months (P 〈 0.001) and at 18 months (P 〈 0.05). Infants with positive skin-prick tests (SPT) to OA and OVO showed higher IgG-Ab levels at 6 and 18 months of age than did infants with negative SPT reactions to the two egg allergens. This indicates a relation between the IgE- and IgG-Ab response and it also suggests that some individuals are ‘high responders’ to both types of immunoglobulin isotypes while others are ‘low responders’.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1991.tb00830.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Serum levels of IgG subclasses in relation to IgE and atopic disease in early infancy (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 20 (1990), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The levels of IgG1, IgG2, IgG3 and IgG4 were analysed by FLISA in cord serum and in serum samples collected at 6 and 18 months of age from infants whose mothers were atopic. None of the four IgG subclasses was significantly influenced on any sampling occasion by infant atopy, gender, month of birth, maternal IgE or maternal diet during pregnancy and early lactation. However, at 18 months of age, significantly higher levels of IgG1 (P 〈 0·05) and of IgG4 (P 〈 0·01) were found in infants with an elevated IgE (〈inlineGraphic alt="geqslant R: gt-or-equal, slanted" extraInfo="nonStandardEntity" href="urn:x-wiley:09547894:CEA407:ges" location="ges.gif"/〉 8·0 kU/1) than in those with a lower level. A weak positive correlation (rs= 0·26; P= 0·05) between IgE and IgG4 was also observed. Despite the fact that the serum levels of IgG4 at 18 months were significantly higher (P 〈 0·01) among infants with positive IgE-RAST (〈inlineGraphic alt="geqslant R: gt-or-equal, slanted" extraInfo="nonStandardEntity" href="urn:x-wiley:09547894:CEA407:ges" location="ges.gif"/〉 0·15 PRU/ml) to ovomucoid or β-lactoglobulin, our data suggest that the the concentration of IgG4 relates more to the level of IgE than to the clinical symptoms of atopy. Determination of IgG subclasses seems to be of limited value for predicting atopy during early infancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1990.tb02802.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Lack of allergenic cross-reactivity between storage mites and Dermatophagoides pteronyssinus (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 17 (1987), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The allergenic cross-reactivity between storage mites (Lepidoglyphus destructor, Glycyphagus domesticus, Tyrophagus putrescentiae and Acarus siro) and the house dust mite Dermatophagoides pteronyssinus was studied with the radio-allergo-sorbent test (RAST) and the RAST inhibition technique. RAST-positive sera were obtained from fifty-three farmers who were positive to at least one of the four storage mites. Sera from twelve of these farmers, eight of whom were also positive to D. pteronyssinus, were investigated with the RAST inhibition technique. No significant correlations were found between IgE-antibody levels to any single storage mite and D. pteronyssinus. There was no correlation between the RAST results to A. siro and G. domesticus, whereas a significant correlation was found between L. destructor, G. domesticus and T. putrescentiae. The RAST inhibition studies confirmed the greater allergenic similarity between L. destructor, G, domesticus and T. putrescentiae than between A. siro and the other three storage mites. The results of our studies support the hypothesis that each of the storage mites and D. pteronyssinus possess their own unique allergen or allergens. Furthermore, L. destructor, G. domesticus and T. putrescentiae seem to be allergenically more closely related to each other than to A. siro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1987.tb02316.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...