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  • 1
    Electronic Resource
    Electronic Resource
    The enteral insulin-stimulation after pancreas transplantation in the pig (1976)
    Springer
    Diabetologia 12 (1976), S. 617-620 
    Details
    ISSN: 1432-0428
    Keywords: Glucose ; incretin ; insulin secretion ; pancreatic transplantation ; pigs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The insulin responses to an oral glucose tolerance test (OGTT) and in intravenous glucose infusion (IVGI), designed to copy the changes in serum glucose concentrations found during OGTT, were measured in four pigs before and after heterotopic pancreatico-duodenal allotransplantation and total pancreatectomy. After transplantation and total pancreatectomy a remarkable hyperinsulinaemia occurred during OGTT and IVGI, reflected by an almost two-fold increment in the insulinogenic index after transplantation. This finding might be explained by drainage of the transplanted pancreas into the systemic circulation instead of the portal vein. The magnitude of the enteral stimulus, i. e. the incretin effect on insulin secretion during OGTT was unchanged after transplantation, suggesting that the incretin effect is not mediated by neural influences upon the endocrine pancreas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01220640
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of intraduodenal and intravenous triglyceride infusions on plasma gastric inhibitory polypeptide and insulin in fetal and neonatal pigs (1982)
    Springer
    Diabetologia 23 (1982), S. 41-44 
    Details
    ISSN: 1432-0428
    Keywords: Gastric inhibitory polypeptide (GIP) ; control ofGIP ; plasma insulin ; insulin secretion ; plasma glucose ; enteroinsular axis ; fetal pigs ; neonatal pigs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The responses of gastric inhibitory polypeptide (GIP) and insulin to intraduodenal and IV triglyceride infusions were measured in 11 late fetal and 10 neonatal pigs. Basal plasma glucose, insulin, and GIP concentrations were lower in fetal than in neonatal pigs. In the fetal pigs, plasma glucose increased slightly during intraduodenal and IV triglyceride infusions, whereas plasma insulin remained unchanged during the tests. No significant changes were observed in plasma GIP concentration following intraduodenal triglyceride infusion in the fetal pigs, but plasma GIP fell during the IV infusion of triglyceride in these pigs (p〈0.01). In the neonatal pigs, plasma glucose and insulin remained unaffected by intraduodenal and triglyceride infusions. Plasma GIP did not change during the IV triglyceride infusion, but exhibited a paradoxical decline after the intraduodenal triglyceride infusion (p〈0.05). It is concluded that the GIP-cell response to an oral triglyceride load is suppressed in late fetal and neonatal pigs. The abolished GIP response to oral triglycerides could play a causal role in the inactivity of the enteroinsular axis which is seen in both human and animal neonates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257729
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  • 3
    Electronic Resource
    Electronic Resource
    Detection of Methane Oxidizing Bacteria in Forest Soil by Monooxygenase PCR Amplification (2000)
    Springer
    Microbial ecology 39 (2000), S. 282 -289 
    Details
    ISSN: 1432-184X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Atmospheric methane oxidation by a spruce forest soil from Norway at 15°C was found to be maximal at a depth of ca 7 cm. Examination of the kinetics of this methane oxidation revealed an apparent K m of 403.1 nM and a V max of 2.2 nmol g-1 dry weight soil h-1. The low apparent K m suggested the presence of active methane oxidizing bacteria with a high affinity for methane. DNA was extracted from the 5–10 cm horizon, purified, and subjected to PCR amplification with primers directed toward the monooxygenase genes pmoA and amoA, which are essential for methane oxidation. Hybridization analysis of the clone library subsequently constructed revealed that 49% of the 76 cloned PCR fragments were putative methanotroph pmoA sequences and 16% were putative ammonium oxidizing nitrifier amoA sequences. Sequencing of 28 clones identified three major groups showing homology to pmoA from Methylococcus capsulatus,β-subdivision ammonia-oxidizers (amoA), and a new group of monooxygenase pmoA/amoA sequences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002480000013
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  • 4
    Electronic Resource
    Electronic Resource
    Die Carotinoide der Thiorhodaceae (1963)
    Springer
    Archives of microbiology 46 (1963), S. 117-126 
    Details
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary Isolation and properties of a new carotenoid are described. It was found in Chromatium okenii as the only carotenoid in a remarkably high concentration (50 μg/mg protein) and is characterized by the presence of a conjugated keto-group and a tertiary methoxyl-group. We suggest to name the new carotenoid okenone. Phytofluene, ξ-carotene, neurosporene and lycopene were found only in cells grown in the presence of diphenylamine.
    Notes: Zusammenfassung Es werden Isolierung und Eigenschaften eines neuen Carotinoids beschrieben. Es liegt in Chromatium okenii als einziges Carotinoid vor, ist in relativ sehr hoher Konzentration (50 μg/mg Protein) enthalten und durch eine konjugierte Ketogruppe und eine tertiäre Methoxylgruppe charakterisiert. Es wird der Name “Okenon” vorgeschlagen. Phytofluen, ξ-Carotin, Neurosporin und Lycopin wurden als Begleitcarotinoide lediglich in Zellen nachgewiesen, die in Gegenwart von Diphenylamin gewachsen waren.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00408204
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  • 5
    Electronic Resource
    Electronic Resource
    Carotenoids of thiorhodaceae (1965)
    Springer
    Archives of microbiology 52 (1965), S. 132-146 
    Details
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Die Carotinoid-Zusammensetzung von 25 Thiorhodaceae-Stämmen wurde untersucht. Aus chemischen und biochemischen Gründen können die 17 aufgefundenen Carotinoide in die Spirilloxanthin-, Okenon- und Warmingon-Reihen zusammengefaßt werden. Die meisten der untersuchten Stämme bilden Carotinoide, die nur zu einer dieser Gruppen gehören, von denen die sogenannte normale Spirilloxanthin-Reihe am häufigsten vorkommt. Das Verteilungsmuster der Carotinoide bei phototrophen Bakterien wird kurz dargestellt und der Wert der Carotinoid-Zusammensetzung für die Taxonomie der Schwefel-Purpurbakterien diskutiert.
    Notes: Summary The carotenoid composition of 25 pure isolates of Thiorhodaceae has been studied. The 17 carotenoids encountered can, on the basis of chemical and biochemical considerations, be grouped into the spirilloxanthin, okenone and warmingone series. Most of the isolates examined synthesize carotenoids belonging to one of these groups only—the so-called normal spirilloxanthin series being the most common. The distribution pattern of carotenoids in phototrophic bacteria in general is briefly discussed, and the implications of the carotenoid composition in the taxonomy of the sulphur purple bacteria are evaluated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00407723
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  • 6
    Electronic Resource
    Electronic Resource
    Die Carotinoide der Thiorhodaceae (1963)
    Springer
    Archives of microbiology 46 (1963), S. 138-149 
    Details
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary Besides lycopene and rhodopin, Chromatium warmingii contains three new carotenoids, not previously described. One (Pigment 3) with a lycopene chromophore, is presumably a hydroxy-derivative of rhodopin (1,2-dihydro-1-OH-lycopene); the second hydroxyl group is secondary. The two other pigments are keto-carotenoids with a common chromophoric system. The main carotenoid, which accounted for 73% of the total carotenoid content of this organism, has been named warmingone (Pigment 2). Warmingone afforded Pigment 3 on LiAlH4-reduction. A close chemical relationship between the carotenoids present has been established, which in turn suggests their biosynthetic interrelationship.
    Notes: Zusammenfassung Chromatium warmingii enthält außer Lycopin und Rhodopin drei weitere bisher nicht beschriebene Carotinoide. Das eine (Pigment 3) mit Lycopin-Chromophor ist wahrscheinlich ein Hydroxy-Derivat von Rhodopin (1,2-Dihydro-1-OH-Lycopin); die zweite Hydroxylgruppe ist sekundär. Die sehr ähnlichen Spektren der beiden anderen gehören zu dem verschwommenen Typus der Keto-Carotinoide. Das Hauptcarotinoid, das zu 73% der Gesamtcarotinoide enthalten war, wurde Warmingon (Pigment 2) genannt. Warmingon, liefert bei LiAlH4-Reduktion Pigment 3. Die für die vorhandenen Carotinoide nachgewiesenen engen chemischen Beziehungen deuten auf ihre biosynthetische Verwandtchaft hin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00408206
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  • 7
    Electronic Resource
    Electronic Resource
    A new isolate of the rhodospirillum fulvum group and its photosynthetic pigments (1965)
    Springer
    Archives of microbiology 51 (1965), S. 258-266 
    Details
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Es wird die Isolierung eines obligat phototrophen Bakteriums beschrieben, welches auf Grund seiner Farbe, Morphologie, Nährstoff-Bedürfnisse und streng anaeroben Lebensweise in die Rhodospirillum fulvum-Gruppe eingeordnet wird. Als einzigen Wachstumsfaktor benötigt der Stamm p-Aminobenzoesäure. Rhsp. fulvum bildet Bacteriochlorophyll a als einzigen chlorophyllartigen Farbstoff. Die Hauptmenge der Carotinoide besteht aus Lycopin (I) und Rhodopin (II); es sind außerdem Spuren von 1,2,1′2′-Tetrahydro-1,1′-dihydroxy-Lycopin (III) nachgewiesen.
    Notes: Summary The present paper reports the isolation of an obligate phototrophic bacterium which belongs to the Rhodospirillum fulvum-group on the basis of its colour, morphology, nutritional requirements and strictly anaerobic nature. p-Aminobenzoic acid was shown to be the only growth factor required. Rhsp. fulvum synthesizes bacteriochlorophyll a as its only chlorophyllous pigments. The carotenoid composition comprises lycopene (I) and rhodopin (II) as the major components; traces of 1,2,1′,2′-tetrahydro-1,1′-dihydroxy-lycopene (III) were also present.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00408142
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  • 8
    Electronic Resource
    Electronic Resource
    Effects of fluoride, calcium, and phosphate administration on mineralization in rats (1980)
    Springer
    Calcified tissue international 31 (1980), S. 225-230 
    Details
    ISSN: 1432-0827
    Keywords: Fluoride metabolism ; Calcium metabolism ; Mineralization ; Dentin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Seven days before a fluoride injection of 20 mg sodium fluoride per kg body weight, 3-month-old rats grown on a standard pellet diet containing 0.8% calcium and 1.4% phosphate were given a diet of rice with only 0.025% calcium and 0.1% phosphate. Microradiographs of the continuously growing incisors showed a hypermineralized and a subsequent hypomineralized zone. Blood analysis demonstrated a decrease and a subsequent reestablishment of plasma calcium concentration. In some experiments calcium and phosphate were administered to compensate the hypocalcemia which prevented the hypomineralized zone from arising. A delay of calcium and phosphate administration led to formation of a mineralized band within the hypomineralized zone. The results are discussed with reference to calcium homeostasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02407185
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  • 9
    Electronic Resource
    Electronic Resource
    Femtosecond photolysis of aqueous HOCl (2001)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 115 (2001), S. 9361-9369 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: This paper reports an experimental study of the photolysis of aqueous HOCl using femtosecond pulses at 266 nm. The formation of photoproducts is monitored by transient absorption spectroscopy from 230 to 400 nm. The HOCl molecules dissociate with unity quantum yield to form OH+Cl faster than 1 ps, and as a result of the potential along the HO–Cl reaction coordinate, all excess energy is given to the fragments as translational energy. After dissociation, and solvent cage escape, the majority of the Cl and OH fragments recombine after diffusion on a time scale of 50 ps. The diffusion dynamics is studied using a simple model for diffusive recombination and a more extensive molecular dynamics simulation. A minor fraction of the Cl atoms (∼10%) reacts with HOCl in a diffusion limited reaction to form Cl2+OH. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1413964
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  • 10
    Electronic Resource
    Electronic Resource
    Contact allergy to colophony (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 20 (1989), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The sensitizing capacity of 15 commercial colophony products was studied experimentally in guinea pigs. The study included 8 French and 6 American colophony derivatives as well as French tall oil colophony. The results indicate that tall oil colophony is the strongest sensitizing material within the tested group and that the maleic-modified products and the zinc-calcium-resinate are moderate sensitizers. Most of the modified products show a higher sensitizing capacity than the genuine resin acids themselves. Cross-reactions between the resin acids and the derivatives are uncommon. Therefore, patch testing with high concentrations of colophony (e.g., 60%) will not help to detect patients with colophony-derivative allergy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1989.tb03122.x
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