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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 76 (1954), S. 4711-4714 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 78 (1989), S. 105-107 
    ISSN: 1432-0533
    Keywords: Angiotropic lymphoma ; Malignant lymphoma ; Nerve ; Neuropathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Angiotropic lymphoma can present as a vascular disease in the central nervous system. The patient described in this report had a sudden pain in the region of the right superficial peroneal nerve and a nerve biopsy showed tumoral cells in the lumen of most small blood vessels. This pathology, first described in the skin as malignant angioendotheliomatosis, can be compared with the occurrence of multiple emboli in the vasa nervorum. In recent cases, tumoral markers have evidenced a lymphomatous origin, generally of the B type.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1424
    Keywords: Key words:Trichoplusia ni insect cells (Hi-5) — Baculovirus — Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel — Glibenclamide — Outwardly rectifying chloride channel (ORCC)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract. Increasing evidence is now accumulating for the involvement of the cystic fibrosis transmembrane conductance regulator (CFTR) in the control of the outwardly rectifying chloride channel (ORCC). We have examined the sensitivity of ORCC to the sulfonylurea drug glibenclamide in Hi-5 (Trichoplusia ni) insect cells infected with recombinant baculovirus expressing either wild-type CFTR, ΔF508-CFTR or E. coliβ galactosidase cDNA and in control cells either infected with virus alone or uninfected. Iodide efflux and single channel patch-clamp experiments confirmed that forskolin and 1-methyl-3-isobutyl xanthine (IBMX) or 7-methyl-1,3 dipropyl xanthine (DPMX) activate CFTR channels (unitary conductance: 9.1 ± 1.6 pS) only in cells expressing CFTR. In contrast, we identified 4-acetamido-4′-isothiocyanatostilbene-2,2′-disulfonic acid (SITS)-sensitive ORCC in excised membrane patches in any of the cells studied, with similar conductance (22 ± 2.5 pS at −80 mV; 55 ± 4.1 pS at +80 mV) and properties. In the presence of 500 μm SITS, channel open probability (P o ) of ORCC was reversibly reduced to 0.05 ± 0.01 in CFTR-cells, to 0.07 ± 0.02 in non-CFTR expressing cells and to 0.05 ± 0.02 in ΔF508-cells. In Hi-5 cells that did not express CFTR, glibenclamide failed to inhibit ORCC activity even at high concentrations (100 μm), whereas 500 μm SITS reversibly inhibited ORCC. In contrast in cells expressing CFTR or ΔF508, glibenclamide dose dependently (IC50= 17 μm, Hill coefficient 1.2) and reversibly inhibited ORCC. Cytoplasmic application of 100 μm glibenclamide reversibly reduced P o from 0.88 ± 0.03 to 0.09 ± 0.02 (wash: P o = 0.85 ± 0.1) in CFTR cells and from 0.89 ± 0.05 to 0.08 ± 0.05 (wash: P o = 0.87 ± 0.1) in ΔF508 cells. In non-CFTR expressing cells, glibenclamide (100 μm) was without effect on P o (control: P o = 0.89 ± 0.09, glib.: P o = 0.86 ± 0.02; wash: P o = 0.87 ± 0.05). These data strongly suggest that the expression of CFTR confers glibenclamide sensitivity to the ORCC in Hi-5 cells.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Personnel psychology 3 (1950), S. 0 
    ISSN: 1744-6570
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Experimental Cell Research 199 (1992), S. 363-372 
    ISSN: 0014-4827
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0014-4827
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé De janvier 1989 à mai 1992, 70 transplantations hépatiques orthotopiques (THO) ont été faites chez 69 malades, dont 53 avaient une cirrhose (77%). Onze patients (16%) avaient une thrombose portale (TP) partielle ou totale préopératoire. Dix d'entre eux avaient une cirrhose d'étiologie variée. La TP totale a été diagnostiquée en préopératoire dans les trois cas. Au contraire, la TP partielle n'a été dépistée en préopératoire que dans trois des huit cas. Chez les cinq autres patients, la TP partielle a été découverte en peropératoire lors de la dissection de la veine porte. Le traitement chirurgical de la TP a consisté en une thrombectomie dans 10 cas suivie d'une anastomose portale terminolatérale conventionelle dans neuf cas et d'une anastomose entre la veine porte du greffon et la jonction spléno-mésentérique dans un cas. Une anastomose atypique entre la veine porte du greffon et une veine cholédocienne dilatée a été utilisée dans un cas de TP totale. Il n'y pas eu de décès ou de complication liée à l'existence d'une TP préopératoire. Une patiente est décédée au cinquième jour postopératoire d'une non fonction du primaire greffon. Un malade a été retransplanté au troisième moin en raison d'une thrombose de l'artère hépatique. Il y a eu deux décès secondaires par récidive cancéreuse à trois et sept mois. Huit patients sont vivants avec un recul de 4–39 mois après la THO. Nos conclusions à partir de cette série sont que: 1) la prévalence de la TP préopératoire chez les patients transplantés pour cirrhose avancée peut être élevée (19% des cirrhotiques dans cette série), 2) la TP est souvent partielle et, alors, difficile à diagnostiquer en préopératoire, 3) la TP, même totale, peut être traitée avec succès au cours de la THO et elle ne semble pas affecter la survie.
    Abstract: Resumen Se realizaron 70 trasplantes ortotópicos de hígado (TOH) entre enero de 1989 y mayo de 1992 en 69 pacientes, 53 (77%) de los cuales tenían cirrosis. Once pacientes (16%) presentaban preoperatoriamente trombosis total o parcial de la vena porta (TVP). Diez de estos pacientes tenían cirrosis de diversas causas. La TVP era total en tres casos y parcial en ocho; la TVP total fue detectada en todos los tres casos pero, en constraste, la TVP parcial fue diagnosticada preoperatoriamente en sólo tres de los ocho casos; en los otros cinco se descubrió la obstrucción en el curso de la disección de la vena porta. El manejo quirurgico de la TVP consistió en flebotrombectomía en diez casos seguida de la anastomosis portal término-terminal usual en nueve y anastomosis de la vena porta del injerto a la confluencia esplenomesentérica en uno. Anastomosis atípica de la vena porta del injerto a una vena coledociana dilatada fue practicada en un caso en TVP total. No se registraron muertes o complicaciones atribuibles a la presencia preoperatoria de TVP o a su manejo. Un paciente murió a los 5 días postoperatorios debido a falla en la función del injerto. Un paciente que desarrolló trombosis arterial tres meses después del TOH y fue exitosamente retrasplantado. Dos pacientes murieron por carcinoma recurrente a los tres y siete meses después del TOH, y ocho se encuentran vivos a los 4–39 meses. En cuanto a esta série, nuestras conclusiones son 1) la prevalencia de TVP preoperatoria en los pacientes trasplantados por cirrosis avanzada puede ser alta (19% de los cirrótico en esta serie), 2) la TVP frecuentemente es parcial y difícil de diagnosticar preoperatoriamente, 3) la TVP, aun si es total, puede ser manejada exitosamente en el curso de la cirugía y no parece afectar la supervivencia.
    Notes: Abstract From January 1989 to May 1992, 70 orthotopic liver transplantations (OLT) were performed in 69 patients, 53 of whom had cirrhosis (77%). Eleven patients (16%) had preoperative partial or total portal vein thrombosis (PVT). Ten of these patients had cirrhosis of various causes. PVT was total in three cases and partial in eight. Total PVT was detected preoperatively in all three cases. By contrast, partial PVT was diagnosed preoperatively in only three of the eight cases. In the five other cases of partial PVT, the obstruction was discovered intraoperatively during dissection of the portal vein. Surgical management of PVT consisted of phlebothrombectomy in ten cases followed by usual end-to-end portal anastomosis in nine cases and anastomosis of the graft's portal vein to the splenomesenteric confluence in one case. Atypical anastomosis of the graft's portal vein to a dilated choledocal vein was performed in one case of total PVT. There were no deaths or complications related to the presence of preoperative PVT or to its management. One patient died postoperatively of primary graft nonfunction at day 5. One patient had arterial thrombosis 3 months after OLT and was successfully retransplanted. Two patients died of recurrent carcinoma 3 and 7 months after OLT. Eight patients are alive 4 to 39 months after OLT. We conclude from this series that (1) the prevalence of preoperative PVT among patients transplanted for advanced cirrhosis may be high (19% of the cirrhotics in this series); (2) PVT is often partial and so difficult to diagnose preoperatively; (3) PVT, even when total, can be managed successfully during surgery and does not seem to affect survival.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-8248
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Résumé La biologie et la spécificité d'une population deLixus cribricollis Boheman provenant du Maroc ont été étudiées en quarantaine en Australie. Les adultes deL. cribricollis vivent longtemps, ils présentent une estivation et sont univoltins. On a montré queRumex cripus L.,Emex australis Steinheil etE. spinosa (L.)Compdere sont les seules plantes hôtes valables parmi les 40 espèces de 17 familles de plantes exposées à des adultes deL. cribricollis sexuellement mûrs. Une alimentation normale et une ponte occasionnelle ont été constatées sur certaines autres plantes de la même famille, lesPolygonaceae, y compris les cultures mineures que sont la rhubarbe et la renouée, mais presque invariablement les larves sont mortes au 1er stade. On en conclut queL. cribricollis peut constituer un utile agent de lutte biologique contre les mauvaises herbes,R. crispus, E. australis etE. spinosa et que l'établissement de ce charançon en Australie serait sans risque pour des plantes non visées.
    Notes: Abstract The biology and host specificity of a colony ofLixus cribricollis Boheman originating in Morocco were studied in quarantine in Australia.L. cribricollis adults are long lived, have an aestivation and are univoltine.Rumex crispus L.,Emex australis Steinheil andE. spinosa (L.)Campdera were shown to be the only satisfactory hosts of 40 species of plants from 17 families that were exposed to sexually mature adults ofL. cribricollis. Normal feeding and occasional oviposition were observed on some other plants within the same family,Polygonaceae, including the minor crops rhubarb and buckwheat, but almost invariably larvae died in the 1st instar. It was concluded thatL. cribricollis may be a useful biological control agent for the weedsR. crispus, E. australis andE. spinosa and that establishment of this weevil in Australia would be without risk to non-target plants.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-8248
    Keywords: Disonycha argentinensis ; alligator weed ; terrestrial growth ; biological control ; Disonycha argentinensis ; milieu terrestre ; lutte biologique ; Alternanthera philoxeroides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Résumé En Australie, la lutte biologique contreAlternanthera philoxeroides, mauvaise herbe se développant en milieu aquatique, a été couronnée de succès mais les auxiliaires utilisés, un ColéoptèreAgasicles hygrophila et un LépidoptèreVogtia malloi sont inefficaces en milieu terrestre. Un autre Coléoptère,Disonycha argentinensis, fut donc introduit en Australie pour lutter contre le développement de cette mauvaise herbe en milieu terrestre. Les descendants des adultes récoltés au Brésil dans des zones similaires par le climat et le biotope à celles où croît la mauvaise herbe en Australie ont été relâchés mais ne se sont pas installés. Des œufs furent pondus par des femelles lâchées dans une grande cage sur le terrain et des adultes ont ainsi été obtenus, mais ceux-ci ne se reproduisirent pas. Cet échec peut s'expliquer par le microclimat ou la prédation qui auraient empêché l'installation deDisonycha argentinensis. Cependant ces résultats ne devraient pas empêcher des essais d'installation de cet insecte en Amérique du Nord, en Chine ou ailleurs.
    Notes: Abstract Biological control of alligator weed growing in aquatic habitats in Australia is successful but the agents, a flea beetleAgasicles hygrophila and a mothVogtia malloi, do not control terrestrial growth. Consequently another flea beetleDisonycha argentinensis was introduced into Australia specifically to control the terrestrial growth. Progeny of adults collected in Brazil from areas similar in climate and habitat to areas infested with alligator weed in Australia, were released but failed to become established. Eggs were laid by females released into a large field cage and some completed development, but the new adults failed to reproduce. Tentative conclusions are that microclimate or predation may have prevented establishment ofD. argentinensis but the results should not preclude attempts to establish this insect in North America, China or elsewhere.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1434-6036
    Keywords: PACS. 75.10.Jm Quantized spin models - 75.40.-s Critical-points effects, specific heats, short range order - 76.60.-k Nuclear magnetic resonance and relaxation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: In a magnetic field, spin-ladders undergo two zero-temperature phase transitions at the critical fields Hc1 and Hc2. An experimental review of static and dynamical properties of spin-ladders close to these critical points is presented. The scaling functions, universal to all quantum critical points in one-dimension, are extracted from (a) the thermodynamic quantities (magnetization) and (b) the dynamical functions (NMR relaxation). A simple mapping of strongly coupled spin ladders in a magnetic field on the exactly solvable XXZ model enables to make detailed fits and gives an overall understanding of a broad class of quantum magnets in their gapless phase (between Hc1 and Hc2). In this phase, the low temperature divergence of the NMR relaxation demonstrates its Luttinger liquid nature as well as the novel quantum critical regime at higher temperature. The general behavior close these quantum critical points can be tied to known models of quantum magnetism.
    Type of Medium: Electronic Resource
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