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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 377-386 
    ISSN: 1420-9071
    Keywords: Molecular parasitology ; Trypanosoma ; Leishmania ; Plasmodium ; helminths ; antigenic variation ; membrane proteins ; kinetoplast DNA ; metabolism ; bioenergetics ; tubulin ; hemoglobin ; anthelmintics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Substantial progress has been made in the last ten years in understanding the structural and functional organization of parasitic protozoa and helminths and the complex physiological relationships that exist between these organisms and their hosts. By employing the new powerful techniques of biochemistry, molecular biology and immunology the genomic organization in parasites, the molecular basis of parasite's variation in surface antigens and the biosynthesis, processing, transport and membrane anchoring of these and other surface proteins were extensively investigated. Significant advances have also been made in our knowledge of the specific and often peculiar strategies of intermediary metabolism, cell compartmentation, the role of oxygen for parasites and the mechanisms of antiparasitic drug action. Further major fields of interest are currently the complex processes which enables parasites to evade the host's immune defense system and other mechanisms which have resulted in the specific adaptations which enabled parasites to survive within their host environments. Various approaches in molecular and biochemical parasitology and in immunoparasitology have been proven to be of high potential for serodiagnosis, immunoprophylaxis and drug design.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 44 (1966), S. 1148-1149 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In seven patients with chronic liver diseases accompanied with haemolytic anaemias a causal connexion of both disturbances could be found. In consequence of a degraded drug clearance of the liver a retention of the drug substance in serum results during permanent application. This retention goes parallel with the haemolytic process. All further applications of the drug in question produce returning haemolysis with non-conjugated bilirubin in serum. These observations demand to make spare of employment of drugs in chronic liver diseases.
    Notes: Zusammenfassung Bei 7 Patienten mit einer chronischen Leberparenchymschädigung und einer begleitenden hämolytischen Anämie konnte nachgewiesen werden, daß zwischen beiden ein ursächlicher Zusammenhang besteht. Infolge der gestörten Entgiftungsfunktion der Leber gegenüber Arzneimitteln kommt es bei häufiger Verabreichung zu einer Retention im Serum. Mit der Retention geht das Auftreten einer Hämolyse parallel. Jede weitere Zufuhr des betreffenden Arzneimittels bewirkt einen erneuten hämolytischen Schub mit Vermehrung von nichtkonjugiertem Bilirubin im Serum. Daraus resultiert die Forderung nach sparsamster Verwendung von Arzneimitteln bei der chronischen Hepatopathie.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 244 (1997), S. 328-332 
    ISSN: 1432-1459
    Keywords: Key words Peroneal neuropathy ; Neoplasm ; Paraneoplastic ; syndrome ; Weight loss
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aims: To investigate the occurrence of symptomatic peroneal neuropathy (PN) in cancer patients, as well as that of cancer in PN patients and to seek possible factors in the aetiology of PN. Methods: Clinical, neurographical, and myographical data of patients with PN, in two general neurology clinics during a 5-year period (1988–1992) were analysed retrospectively. A population-based cancer registry was consulted for epidemiological data in the area. Results: The catchment population of the two clinics consisted of 433,142 people, and 8,766 new cancer patients were diagnosed. PN was diagnosed in 372 patients, of whom 74 suffered from cancer (in 56 PN was believed to be related to cancer). The crude relative risk of PN in patients with cancer compared with patients without cancer was 8.6. After correction for differences in age and sex between the compared groups, the relative risk dropped to 3.4 (2.8 for women and 3.6 for men). The crude relative risk of cancer for patients with PN relative to people without PN was 7.5. The relative risk, after correction for age and sex, was 2.8 (2.5 for women and 2.9 for men). All relative risks were significant (P 〈 0.001), but did not differ between the sexes (P 〉 0.4). Weight loss was established in 35/56 patients, but in 17/56 it was unknown. PN has not been found to be part of a polyneuropathy. Chemotherapy did not play a causal part. In some patients PN preceded the diagnosis of cancer. Conclusions: The occurrence of PN seems to be higher in patients with cancer than in people without cancer. Cancer was found in patients with PN more often, particularly in elderly men, than would be expected from the occurrence in the total population. PN in patients with cancer is supposed to be due to a combination of metabolic and mechanical factors. The findings justify a prospective study of the relation between PN and cancer.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 116 (1992), S. 62-64 
    ISSN: 0942-0940
    Keywords: Orbital encephalocele ; pulsating eye ; head injury ; hydrocephalus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A patient is reported with unilateral intermittent pulsating eye caused by the combination of an orbital encephalocele and hydrocephalus, thirty four years after a head injury. Treatment of the hydrocephalus resulted in disappearance of the eye pulsations and encephalocele, as well as in improvement of the gait.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Numerische Mathematik 72 (1995), S. 93-116 
    ISSN: 0945-3245
    Keywords: Mathematics Subject Classification (1991):41A55, 65D30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary. We show that, for integrals with arbitrary integrable weight functions, asymptotically best quadrature formulas with equidistant nodes can be obtained by applying a certain scheme of piecewise polynomial interpolation to the function $f$ to be integrated, and then integrating this interpolant.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: There was no apparent effect on drained weight or firmness when three rates of calcium fertilization and two rates of potassium fertilization were applied to a test planting from which two harvests of raw summer squash were canned. However, high Ca (L2) decreased dry matter and increased structural carbohydrates and tissue Ca in the canned product. Precooling increased drained weight and dry matter, but drastically reduced firmness of the canned product. Noncooled canned squash had lower drained weights and pH, but greater firmness and higher water soluble pectin and cellulose content. Blanching at 99°C increased drained weight; blanching at 88°C decreased drained weight, but increased calgonsoluble pectin content.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 46 (1981), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A mutant, Monascus purpureus G1, was isolated from a wildtype which had been transferred for several times after ultraviolet irradiation. This new strain is extremely dark red in color and also releases more pigment into the yeast extract cultural medium. Unlike strain N11S, another strain of high pigment productivity, G1 is extremely low in antibacterial activity. Sonification for 30 min increased the rate of pigment extraction.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 44 (1979), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The sampling distributions of aflatoxin in fresh and roasted pecans, visible mycelium in fresh pecans and total plate count in ground beef were examined using the chi-square and Kolmogorov-Smirnov tests. The Kolmogorov-Smirnov test was found to be more conservative than the chi-square test and a powerful technique for rejection of null hypotheses. The results indicated that many sampling distributions used in quality control of foods deviate significantly from the normal distribution. The sampling distribution for total plate count in ground beef and the distribution of sample means were determined. A critical sample size of at least 5 was found to be necessary to approximate the normal distribution for the sample means. The average and standard deviation control charts utilizing the sample size of 5 were established to illustrate the detection of out-of-control samples.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 41 (1976), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: White potatoes did not support the growth of A. parasiticus NRRL 2999 unless they were heated to above 60° C. The mold grew well on autoclaved potatoes and produced, on an average, 8 μg/g total aflatoxins (mainly B1 and G1) at 27°C and 95–97% relative humidity in 20 days. When soluble potato starch was substituted for sucrose in yeast extract-sucrose (YES) medium, the maximum growth of A. purasiticus was 80% of that observed in YES medium, but total aflatoxin production was only 0.5–1.0% of the production in YES medium. Chlorogenic acid and solanine, at levels normally found in the white potato, did not show appreciable fungitoxic activity towards A. parasiticus in vitro. Caffeic acid partially inhibited the growth of A. parasiticus and the production of aflatoxins at 0.01M concentration in YES medium. A compound with high inhibitory activity towards A. parasiticus was isolated from the potatoes. The compound is extractable with ethyl acetate. From its behavior on TLC systems, its ultraviolet spectrum and its reactions with chromagenic spray reagents, it is inferred that the compound is phenolic in nature. It appears to be a hydroxy-cinnamic acid derivative structurally similar to caffeic acid but lacking the ortho-dihydroxy structure of caffeic acid.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 43 (1978), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Factors influencing tyramine formation and the presence of tyrosine decarboxylase activity in natural microflora and starter (Pediococcus cerevisiae) fermented sausages were determined. Maximal levels of tyrosine decarboxylase were found during the period of rapid acid development in the natural microflora fermentations. Higher levels of decarboxylase were present in the natural fermented sausages compared to the starter fermented sausages. Tyrosine decarboxylase activity increased during the drying treatment in the natural microflora sausages but remained low in the starter fermented sausages. Greater tyramine contents were found in the natural microflora sausages which had free L-tyrosine added prior to fermentation. Tyramine contents of the natural microflora and starter fermented sausages without added L-tyrosine generally reached similar tyramine levels. In the starter fermented sausages, tyramine and tyrosine decarboxylase development comparable to the amounts found in natural microflora fermented sausages occurred only in a sausage which contained added L-tyrosine that was inoculated with a tyrosine decarboxylase positive Streptococcus faecalis. The study indicated that the natural meat microflora developed during the aging of salted meat can develop tyrosine decarboxylase activity necessary for rapid conversion of tyrosine to tyramine. The use of a starter culture such as P. cerevisiae appears to decrease the possibility of development of a microflora during fermentation that would possess both tyrosine decarboxylase activity and proteolytic activity necessary to produce fermented sausages with potentially hazardous tyramine concentration.
    Type of Medium: Electronic Resource
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