ISSN:
1420-9071
Keywords:
α 1-Adrenoceptor
;
pertussis toxin
;
inositol phosphates
;
myocardial hypertrophy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary In neonatal rat ventricular myocytes pretreatment with pertussis toxin did not affect 1 μM (−)-norepinephrine stimulation of inositol phosphates or myocardial cell hypertrophy as measured either by protein radiolabelling or by myocardial cell protein content. Thus guanine nucleotide protein (s) ADP-ribosylated by pertussis toxin do not play a role in twoα 1-adrenoceptor-mediated processes, phosphatidylinositide turnover and induction of myocardial cell hypertrophy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01955423
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