Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Anaesthesist 44 (1995), S. 230-241 
    ISSN: 1432-055X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The objective of the study was to evaluate the role of autologous blood transfusion in current clinical practice in the Federal Republic of Germany after reunification. Methods. Questionnaires were sent to the anaesthesia departments of 684 German hospitals in January 1993. The sample consisted of 400 randomly selected hospitals from the former West Germany (“old federal states”) and 284 hospitals from the former German Democratic Republic (“new federal states”). Only hospitals with more than 25 surgical beds were included in the study. The questionnaire contained 36 questions related to (1) general information on the hospital, (2) preoperative autologous blood donation (PABD), (3) preoperative plasmapheresis, (4) isovolaemic haemodilution, (5) perioperative blood salvage, and (6) general management of blood transfusion.
    Notes: Zusammenfassung Im Januar 1993 wurde eine Fragebogenerhebung zum Einsatz autologer Transfusionsverfahren in der Bundesrepublik Deutschland durchgeführt. Befragt wurden die leitenden Anästhesisten von 400 Krankenhäusern aus den alten und 284 Krankenhäusern aus den neuen Bundesländern. 502 Fragebögen (73%) wurden ausgefüllt zurückgesandt (305 aus den alten und 197 aus den neuen Bundesländern). 9% der antwortenden Krankenhäuser hatten eine eigene transfusionsmedizinische Abteilung. Die präoperative Eigenblutspende stand in 80% der antwortenden Krankenhäuser zur Verfügung, wurde jedoch nur in 1 / 5 davon (16%) regelmäßig eingesetzt. Organisiert und durchgeführt wurde sie zu über 50% von der Anästhesieabteilung der Klinik. Präoperative Plasmapheresen wurden in 12% der antwortenden Kliniken durchgeführt. Die isovolämische Hämodilution wurde in 75% der antwortenden Krankenhäuser nie oder nur gelegentlich, in 16% häufig und in 8% regelmäßig durchgeführt. Verfahren zur Rückgewinnung perioperativer Blutverluste kamen in 41% der antwortenden Krankenhäuser zum Einsatz (maschinelle Autotransfusion in 30%, Autotransfusion mittels einfacher Filter-/Sammelsysteme in 11%, beide Methoden in 5%).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-055X
    Keywords: Schlüsselwörter Autologe Bluttransfusion ; Bundesrepublik Deutschland ; Umfrageergebnisse ; Key words Autologous blood transfusion ; Federal Republic of Germany ; Survey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract In 1993, we conducted a postal survey to assess the use of autologous blood transfusion (ABT) in the Federal Republic of Germany after reunification. The results of this survey have already been reported in a previous paper, but without differentiation between the “old” and “new” states (former West Germany and former German Democratic Republic, respectively). In the present study, the data of our 1993 survey were further analysed to see if there were differences in the use of ABT between the “old” and “new” states. Methods. The study is based on data of a 1993 postal survey of German hospitals. Details concerning the performance of the survey have been reported in a previous paper. Briefly, questionnaires were mailed to the anaesthesia departments of 400 randomly selected hospitals in the “old” states and 284 hospitals in the “new” states of the Federal Republic of Germany. The questionnaires contained 36 questions related to general information on the hospital and the use of ABT; 305 completed questionnaires were returned from the “old” states and 197 from the “new” states, response rates of 76% and 69%, respectively. For the present investigation, the responses of the hospitals of the “old” and “new” states were analysed separately. Frequency distributions of categorical variables were analysed by the chi-square test. Because of multiple testing, statistical significance was attained only at the 0.05% level (P≤0.0005). Results. There were no significant differences between the “old” and “new” states with respect to hospital size by number of beds, percentage of general and specialised hospitals, and percentage of operations requiring blood transfusion. In both the “old” and “new” states, 9% of the responding hospitals maintained a hospital-based transfusion service, while the other depended on regional blood banks. Preoperative autologous blood donation (PABD) was performed at least “rarely” in 85% and 71% (P=0.0001), and “mostly” in 20% and 10% (P=0.0014) of the hospitals in the “old” and “new” states, respectively. Uniformly, the principal uses of PABD were for orthopaedic and cardiac surgery. In 62% and 27% (P〈0.0001) of those hospitals that reported performing PABD, the autologous blood service was run by the anaesthesia department. Preoperative plasmapheresis was performed in 14% and 8% (P=0.008), and isovolaemic haemodilution in 82% and 56% (P〈0.0001) of the hospitals in the “old” and “new” states, respectively. Automated autotransfusion devices (cell savers) were available in 38% and 19% (P〈0.0001) of the hospitals, respectively. Simple collection devices for perioperative blood salvage were used in 17% and 15% (P=0.24) of the hospitals in the “old” and “new” states, respectively. Conclusion. We conclude that ABT is more widely used in the “old” than the “new” states of the Federal Republic of Germany. ABT is regarded as a desirable alternative to homologous blood transfusion, and in the interest of equal standards of medical care throughout the nation, the use of ABT should be further promoted, especially in the “new” states of the Federal Republic of Germany.
    Notes: Zusammenfassung Die Verbreitung autologer Bluttransfusionsverfahren in den alten und neuen Bundesländern wird miteinander verglichen. Dem Vergleich liegen die Ergebnisse einer Fragebogenerhebung aus dem Jahre 1993 zugrunde, über die wir ohne Unterscheidung zwischen alten und neuen Bundesländern bereits berichteten. Bei der Umfrage waren 400 Krankenhäuser aus den alten und 284 Krankenhäuser aus den neuen Bundesländern zur Praxis der autologen Bluttransfusion um Auskunft gebeten worden. 305 bzw. 197 Krankenhäuser (76% bzw. 69%) hatten geantwortet. Die beiden Antwortkollektive waren nach der Krankenhausbettenzahl, der Versorgung durch transfusionsmedizinische Einrichtungen und dem Aufkommen an Eingriffen mit Transfusionsbedarf nicht signifikant verschieden. In 85% bzw. 71% der Krankenhäuser (alte bzw. neue Bundesländer) war eine präoperative Eigenblutspende möglich. Der Anteil der Krankenhäuser, in denen dieses Verfahren „meistens“ eingesetzt wurde, war in den alten Bundesländern doppelt so hoch wie in den neuen Bundesländern (20% bzw. 10%). 82% bzw. 56% der Krankenhäuser (alte bzw. neue Bundesländer) machten zumindest fallweise von der Möglichkeit der akuten isovolämischen Hämodilution Gebrauch. Die präoperative Plasmapherese und die maschinelle Autrotransfusion waren in den alten Bundesländern doppelt so weit verbreitet wie in den neuen Bundesländern (14% bzw. 8% und 38% bzw. 19% der Krankenhäuser). Die Untersuchung hat gezeigt, daß bezüglich der Verbreitung autologer Transfusionsverfahren in den neuen Bundesländern ein erheblicher Nachholbedarf gegenüber den alten Bundesländern besteht.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1432-055X
    Keywords: Schlüsselwörter Autologe Bluttransfusion ; Bundesrepublik Deutschland ; alte Bundesländer ; Key words Autologous blood transfusion ; Federal Republic of Germany ; “Old” federal states
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Increased perception of the risks of homologous blood transfusion has focused substantial interest on autologous blood transfusion (ABT). To evaluate the role of ABT in the Federal Republic of Germany (FRG), we conducted postal surveys of German hospitals in 1989 and 1993. In the present study, the responses of 143 hospitals in the “old” federal states (former West Germany) that replied to both of our surveys were analysed. The objective was to examine trends in ABT practice in the FRG from 1989 to 1993. The study was restricted to the “old” federal states because data for the “new” federal states (former German Democratic Republic) were not available for that period. Methods. Data presented in this study were obtained by postal surveys of German hospitals in 1989 and 1993. Because of German reunification (3 October 1990), only hospitals in the “old” federal states were surveyed in 1989, while hospitals in both the “old” and “new” states were included in 1993. Four hundred randomly selected hospitals in the “old” federal states were included in both surveys, 143 of which responded to both. The completed questionaires of these 143 hospitals were analysed. In addition, to estimate the magnitude of positive selection bias, the data provided by these 143 hospitals were compared with data provided by another set of 162 hospitals in the “old” federal states that replied to the 1993 but not to the 1989 survey. Results. There were no significant changes from 1989 to 1993 in the 143 hospitals with respect to hospital size by number of beds and spectrum of surgical specialties. The proportion of hospitals that performed preoperative autologous blood donation grew by 20% (from 74% to 89%) and the proportion that used this technique regularly (“frequently” and “mostly”) rose by 80% (from 25% to 45%). The percentage of hospitals that performed preoperative plasmapheresis had more than doubled (from 8% to 19%). The proportion that used acute isovolaemic haemodilution grew by 32% (from 62% to 82%), while those doing so regularly (“frequently” and “mostly”) increased by only 17% (from 23% to 27%). The fraction of hospitals equipped with cell-washing devices grew by 29% (from 35% to 45%). General transfusion practice, as measured by acceptance of postoperative haemoglobin levels of less than 10.0g/dl, had changed but little. Conclusions. Although the 143 hospitals are not representative on a national level, the findings of our study allow some conclusions on general trends in the “old” states of the FRG. The potential for ABT has substantially grown in the “old” states from 1989 to 1993, although more consistent advantage of this potential could be taken.
    Notes: Zusammenfassung In der Arbeit wird die jüngere Entwicklung der autologen Bluttransfusion in 143 Krankenhäusern aus den alten Bundesländern dargestellt. Die Daten stammen aus zwei in den Jahren 1989 bis 1993 von uns durchgeführten Fragebogenerhebungen. Der Anteil der Krankenhäuser, in denen eine präoperative Eigenblutspende möglich war, ist von 74% auf 89% und der Anteil der Krankenhäuser, in denen sie „häufig“ oder „meistens“ durchgeführt wurde, von 25% auf 45% angestiegen (20% bzw. 80% Zuwachs). Die Verbreitung der präoperativen Plasmapherese hat sich mehr als verdoppelt: 1989 wurde sie in 8% und 1993 in 19% der Krankenhäuser eingesetzt. Der Anteil der Krankenhäuser, in denen eine akute isovolämische Hämodilution durchgeführt wurde, ist von 62% auf 82% angestiegen (32% Zuwachs). Der Anteil der Krankenhäuser, in denen Zellseparatoren zur Verfügung standen, hat von 35% auf 45% zugenommen (29% Zuwachs). Die Transfusionspraxis hat sich, gemessen an der Akzeptanz postoperativer Hämoglobinwerte unter 10,0 g/dl, kaum gewandelt. Die Entwicklung der autologen Bluttransfusion in den 143 Krankenhäusern ist für die alten Bundesländer nicht repräsentativ. Sie gestattet aber Rückschlüsse auf die allgemeine Entwicklung der autologen Bluttransfusion in den alten Bundesländern.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1432-055X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Affective Disorders 19 (1990), S. 243-248 
    ISSN: 0165-0327
    Keywords: Depression ; Phototherapy ; Seasonal affective disorder
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Molecular and Cellular Neuroscience 4 (1993), S. 418-423 
    ISSN: 1044-7431
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We compared the pharmacokinetics, pharmacodynamics and safety profile of a new galenic formulation of propofol (AM149 1%), which does not contain soyabean oil, with a standard formulation of propofol (Disoprivan® 1%). In a randomised, double-blind, cross-over study, 30 healthy volunteers received a single intravenous bolus injection of 2.5 mg.kg−1 propofol. Plasma propofol levels were measured for 48 h following drug administration and evaluated according to a three-compartment model. The pharmacodynamic parameters assessed included induction and emergence times, respiratory and cardiovascular effects, and pain on injection. Patients were monitored for side effects over 48 h. Owing to a high incidence of thrombophlebitis, the study was terminated prematurely and only the data of the two parallel treatment groups (15 patients in each group) were analysed. Plasma concentrations did not differ significantly between the two formulations. Anaesthesia induction and emergence times, respiratory and cardiovascular variables showed no significant differences between the two treatment groups. Pain on injection (80 vs. 20%, p 〈 0.01) and thrombophlebitis (93.3 vs. 6.6%, p 〈 0.001) occurred more frequently with AM149 than with Disoprivan®. Although both formulations had similar pharmacokinetic and pharmacodynamic profiles the new formulation is not suitable for clinical use due to the high incidence of thrombophlebitis produced.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Psychiatric Research 25 (1991), S. 75-87 
    ISSN: 0022-3956
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Psychiatry Research 28 (1989), S. 227-239 
    ISSN: 0165-1781
    Keywords: Seasonal affective disorder ; cluster analysis ; depression ; seasonality
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 0165-1781
    Keywords: Immune function ; depression ; lymphocyte blastogenesis ; lymphocyte subtypes ; phototherapy ; seasonal affective disorders
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...