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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Chemical reviews 29 (1929), S. 199-200 
    ISSN: 1520-6890
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1438-2199
    Keywords: Amino acids ; Dansyl amino acids ; Cyclodextrin ; Capillary electrophoresis ; Organic modifiers ; Enantioselectivity ; Chiral resolution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Using capillary electrophoresis, the enantiomers of a number of dansyl amino acids were resolved using nativeβ-cyclodextrin. The neutral chiral host resolved analytes possessing a negative charge at pH 9, the conditions employed in this study. Organic modifiers added to the running buffer were particularly adept at enhancing chiral recognition between the guest and host molecule in capillary electrophoresis. This work examined the effects of methanol, dimethylformamide, and acetonitrile on the resolution, migration time, and efficiency of twelve dansyl amino acids. Examples are given of the separation of racemic dansyl amino acids utilizing this technique and conditions necessary to achieve enantioselectivity.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Genetica 86 (1992), S. 127-142 
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract This paper examines a model in which transposable elements provide a modular architecture for the cellular genome, complemented by cellular recombinational transformations, arising in turn as a dynamical consequence of this modular structure. It is proposed that the ecology of transposable elements in a given organism is a function of recombinational protocols of the evolving cellular genome. In mammals this is proposed to involve coordinated meiosis-phased activation of LINEs, SINEs and retrogenes complemented by endogenous retroviral transfer between cells.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Origins of life and evolution of the biospheres 12 (1982), S. 405-425 
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract Several models have been advanced, both in this journal and others, for the development of the genetic code and translation apparatus. Eigen in particular has put forward a detailed model based on the hypercycle. This paper uses some of these previous ideas to develop a new model of the code and translation in which the pairs AU and GC play complementary roles, and in whichtRNAs develop from a molecule withtwo loops which stacks in repetitive patterns without the need for a messenger RNA. Thus a bridge is provided between random, (or autocatalytic) polymerization, and coded translation. In addition, alternative postulates to several of Eigen's ideas are tested by computer simulation.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Origins of life and evolution of the biospheres 20 (1990), S. 15-25 
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract The discovery of RNA-based enzymes, such as ribonuclease-P, has stimulated new interest in the idea that catalytic functions of RNA preceded the use of coded enzymes during an era loosely termed ‘the RNA world’. This paper examines various lines of evidence which support the idea that electrochemical processes associated with the membrane may have preceded the development of coded protein enzymes and may have provided a basis for the phosphorylation energy of the RNA world.
    Type of Medium: Electronic Resource
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