ISSN:
1432-2013
Keywords:
Triiodothyronine
;
NaK-ATPase
;
Submandibular gland
;
Parotid gland
;
Sublingual gland
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The present studies concern the effect of triiodothyronine (T3) on rat salivary (Na++K+)-adenosine triphosphatase (NaK-ATPase). The results indicate that T3 selectively increased submandibular and parotid NaK-ATPase units with a single, large dose of T3, different dosage of T3, three successive doses of T3 given on alternate days, and “physiological” doses of T3 with daily injection for 2 weeks. Sublingual NaK-ATPase was insensitive to T3 in the above experiments. The effect of T3 on submandibular and parotid NaK-ATPase is selective since Mg-ATPase and 5′-nucleotidase showed no significant differences under different thyroid status. The lack of response of NaK-ATPase to reverse T3, further substantiates the specificity of T3 on salivary NaK-ATPase.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00581261
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