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  • 1
    Electronic Resource
    Electronic Resource
    Choroidal vascular repair: Scanning and transmission electron microscopy (1992)
    Springer
    Cellular and molecular life sciences 48 (1992), S. 219-225 
    Details
    ISSN: 1420-9071
    Keywords: Krypton laser photocoagulation ; choriocapillaris ; neovascularization ; vascular casts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Repair of the choroidal vasculature following laser photocoagulation in the rat was examined with vascular casts and correlated with observations on thin-sections. The regenerative process began at the periphery of the damaged area, starting from the surviving choriocapillaris and venules, and proceeding towards the center by means of recanalization of damaged vessels and growth of new ones. In small healed lesions the capillary bed was re-formed. It resembled the adjacent undamaged choriocapillaris morphologically but appeared to be less dense than the intact choriocapillaris when examined by scanning microscopy. In large lesions the capillary bed was re-formed at the periphery but not at the center. Also present at the edges of the large lesions were groups of new vessels which, when observed by scanning microscopy, appeared to extend in two directions; towards the subretinal space and towards the choroidal network. Another aspect of the repair process was the simultaneous occurrence of new vessel growth and capillary regression, which was observed both at the level of the choriocapillaris and at the foci of new vessels
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01930458
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Intercellular junctions of hyperplastic retinal pigment epithelium (1986)
    Springer
    Cellular and molecular life sciences 42 (1986), S. 812-815 
    Details
    ISSN: 1420-9071
    Keywords: Retinal pigment epithelium ; epithelium ; permeability ; hyperplasia ; pathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In rats with retinopathies induced by excess fluorescent light or injections of urethane, the retinal pigment epithelium (RPE) undergoes focal hyperplasia. Neither intravascularly injected horseradish peroxidase or lanthanum nitrate penetrated the sensory retina at these hyperplastic sites. Electron microscopy revealed that this was due to the persistence of intact, tight junctions among a single layer of hyperplastic cells facing the sensory retina. These junctions prevented intraocularly injected microperoxidase from passing as well. Cells within the hyperplastic foci were connected only by adherent junctions that presented no permeability barrier.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01941533
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Carbonic anhydrase type II in regenerating retinal pigment epithelium. A histochemical study in the rabbit (1993)
    Springer
    Cellular and molecular life sciences 49 (1993), S. 789-791 
    Details
    ISSN: 1420-9071
    Keywords: Carbonic anhydrase ; eye ; histochemistry ; regeneration ; retina ; retinal pigment epithelium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Type II carbonic anhydrase (CAII) in the cytoplasm of the retinal pigment epithelium (RPE) may contribute to the transport of water and solutes across the RPE. The activity of this enzyme in RPE during its response to damage, e.g., during regeneration, is therefore of interest in understanding retinal disease. Immuno-histochemistry was used to compare CAII activity of normal RPE and RPE experimentally induced to regenerate. In normal rabbits, the RPE stained intensely with a peroxidase-linked antibody specific for human CAII. Regenerating RPE stained less intensely. Within the regenerating epithelium, staining appeared more intense in mature cells than in immature ones, suggesting that CAII activity gradually returns during RPE regeneration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01923549
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    Paper (German National Licenses)
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