ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The structure of phenolic metabolites of oxaprotiline, obtained from a study with rats and dogs, are assigned with NMR-spectroscopic methods in combination with MS data and an X-ray structure analysis of synthetic (9R*,2′S*)-2-chlorooxaprotiline, the metabolites are shown to be (9R*,2′R*)-2-hydroxy, 3-hydroxy-, and 2-hydroxy-3-methoxyoxaprotiline, and (9R*,2′S*)-2-hydroxy-, 3-hydroxy-, and 3-hydroxy-2-methoxyoxaprotiline, as well as 2,6-dihydroxyoxaprotiline.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19840670809
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