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  • 1
    Electronic Resource
    Electronic Resource
    Spouse involvement in the treatment of obsessive-compulsive patients
    Amsterdam : Elsevier
    Behaviour Research and Therapy 21 (1983), S. 341-346 
    Details
    ISSN: 0005-7967
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-7967(83)90002-5
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  • 2
    Electronic Resource
    Electronic Resource
    The transfer of cephradine across the placenta (1984)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 91 (1984), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The transfer of maternally administered cephradine (1 g given intravenously) to the fetal circulation and amniotic fluid was investigated in 2 pregnant patients undergoing fetoscopy. Cephradine was detected in fetal serum between 23 and 72 minutes after injection and was present in therapeutic concentrations. Fetal serum levels appeared to peak at approximately 40–50 min. Amniotic fluid levels were rising during the sampling period of 97 min. Cephradine is transferred across the placenta and appears to be a suitable antibiotic for use in selected obstetric patients when penetration of the fetal compartment is desirable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1984.tb04801.x
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  • 3
    Electronic Resource
    Electronic Resource
    Fetoscopy in the assessment of unexplained fetal hydrops (1985)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 92 (1985), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Pure fetal blood samples, obtained fetoscopically from 30 patients with unexplained fetal hydrops at 16 to 32 weeks gestation were investigated for cytogenetic, haematological, biochemical and virological properties. In two patients with oligohydramnios, the fetoscope was introduced transabdominally into the fetal peritoneal cavity and sampling was undertaken from the intra-abdominal portion of the umbilical vein; in all the other patients an umbilical cord vessel was sampled. Ten (33%) of the fetuses had chromosomal abnormalities, one an erythroblastic process, possibly erythroleukaemia, one α-thalassaemia and one cytomegalovirus infection. Blood-film abnormalities were seen in 23 (88%) of 26 fetuses that had this examination. Biochemical analysis of fetal plasma was undertaken in 18 fetuses and hypoproteinaemia was found in all cases. One fetus was subsequently found to have a paroxysmal tachyarrhythmia that responded to digitilization. Three (10%) of the fetuses survived.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1985.tb01446.x
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  • 4
    Electronic Resource
    Electronic Resource
    Polysulfonylamine - XLVII. Darstellung und Kristallstrukturanalyse der ionischen Verbindung catena-Poly[(mu-4,4-bipyridin)trimethylzinn]-dimesylamid-Acetonitril (1/1)
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 458 (1993), S. 57-61 
    Details
    ISSN: 0022-328X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-328X(93)80457-M
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  • 5
    Electronic Resource
    Electronic Resource
    Polysulfonylamine - LII. Darstellung neuer Triorganozinn(IV)-disulfonylamide. Festkorperstrukturen von Ph3SnN(SO2Me)2, cHex3SnN(SO2Me)2 und Ph3SnN(SO2Me)2 Ph3SnOH 2MeCN
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 467 (1994), S. 169-180 
    Details
    ISSN: 0022-328X
    Keywords: Amide ; Crystal structure ; Sulfonyl ; Tin,
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-328X(94)80003-0
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  • 6
    Electronic Resource
    Electronic Resource
    Polysulfonylamine - LIII. Triphenylphosphinoxid-Komplexe von Organozinn(IV)-dimesylamiden: Darstellung und Festkorperstrukturen ionischer Komplexe des Typs [R3Sn(OPPh3)2]+[(MeSO2) 2N]- und des Molekulkomplexes [Me2Sn{OS(:O, Me)NSO2Me}2(OPPh3)2]
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 474 (1994), S. 97-106 
    Details
    ISSN: 0022-328X
    Keywords: Crystal structure ; Dimesyl amide ; Phosphine oxide ; Tin ; X-ray diffraction
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-328X(94)84051-2
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  • 7
    Electronic Resource
    Electronic Resource
    Direkte versus videovermittelte Elternschulung bei atopischem Ekzem im Kindesalter als Ergänzung fachärztlicher Behandlung Eine kontrollierte Pilotstudie (2000)
    Springer
    Der Hautarzt 51 (2000), S. 401-411 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Atopisches Ekzem ; Kinder ; Elternschulung ; Video ; Mütter ; Key words Atopic eczema ; Parental education ; Video ; Children ; Mothers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Background and Objective. Psychological problems in children and parents related to children's atopic eczema (AE) may impede the success of treatment. We studied the question, if behavior-based parental education in groups (DPE) or standardized video-education (VPE) could enhance dermatological treatment effects and reduce skin-damaging behaviors in children and stress in their mothers. Patients/Methods. 47 mothers attending the university outpatient-clinic for dermatology and their AE-children (mean age 4 years) participated in the study. 18 mothers underwent the DPE (10 sessions), 15 mothers worked with VPE at home. Dermatological standard treatment (CG; N=14) served as control for a 16-weeks-evaluation-period. Results. AE-symptoms improved overall, but the effectiveness of the treatments differed significantly, improval with parent education and was best with VPE. Psychological problems of mothers were equally reduced with DPE and VPE. Conclusions. It is suggested that VPE is a cost effective and less time consuming method for supporting dermatological therapy of AE in children.
    Notes: Zusammenfassung Hintergrund und Fragestellung. Das atopische Ekzem (AE) im Kindesalter kann psychologische Probleme bei Kind und Eltern zur Folge haben, die den Behandlungserfolg erschweren. Die Effektivität direkter verhaltensorientierter Elterngruppenschulungen (DES) bzw. standardisierter Videoschulungen (VES) gegenüber der dermatologischen Standardbehandlung (KG) zur Besserung des AE, des Kratzverhaltens der Kinder und krankheitsbedingter Belastungen der Mütter wurde überprüft. Patienten/Methodik. An der Studie nahmen 47 Mütter und deren AE-Kinder (Durchschnittsalter 4 Jahre) aus der Neurodermitisambulanz der Universitätshautklinik teil, 18 Mütter besuchten die DES (10 Gruppensitzungen), 15 Mütter arbeiteten mit der VES zu Hause. Die Behandlung der KG (n=14) erfolgte im vergleichbaren 4-Monats-Zeitraum. Ergebnisse. Das AE war über alle Behandlungsbedingungen gebessert, ihre Effekstärken unterschieden sich jedoch signifikant: Elternschulungen waren effektiver als Standardbehandlung, den stärksten Effekt hatte die VES. Belastungen der Mütter reduzierten sich nach beiden Schulungsformen. Schlussfolgerungen. Die Ergebnisse verweisen auf eine Zeit und Kosten sparende Möglichkeit, Videoschulungen für die Unterstützung der Therapie des AE im Kindesalter zu nutzen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050051141
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  • 8
    Electronic Resource
    Electronic Resource
    Mechanism of non-catalytic proton exchange in aprotic low-polar solvents (1979)
    Springer
    Reaction kinetics and catalysis letters 11 (1979), S. 35-38 
    Details
    ISSN: 1588-2837
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Abstract Методом динамического1H и2H ЯМР изучена кинетика протонного обмена в системах CD3OH−(CH3)3COH и CD3OH−CH3COOH в различных растворителях. Обсуждён механизм исследованного процесса.
    Notes: Abstract The kinetics of proton exchange for the CD3OH−(CH3)3COH and CD3OH−CH3COOH systems in various solvents have been studied by dynamic1H and2H NMR. The mechanism of the process is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02098330
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  • 9
    Electronic Resource
    Electronic Resource
    Transforming growth factor-β1 (TGF-β1) levels in plasma of patients with prostate cancer and benign prostatic hyperplasia (BPH) (1998)
    Springer
    Der Urologe 37 (1998), S. 199-202 
    Details
    ISSN: 1433-0563
    Keywords: Key words Growth factor • TGF-β1 • Prostate cancer • Benign prostate hyperplasia ; Schlüsselwörter Wachstumsfaktor • TGF-β1 • Prostatakarzinom • Benigne Hyperplasie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung „Transforming growth factor-β1“ (TGF-β1) ist ein pleiotroper Wachstumsfaktor und ein wichtiger Regulator der Zellfunktion. In einer prospektiven Studie haben wir den Stellenwert der Plasmakonzentration von TGF-β1 bei Patienten mit einem Prostatakarzinom untersucht. Gemessen wurde die TGF-β1-Konzentration bei insgesamt 394 Patienten. Bei 242 Patienten (Gruppe I) erfolgte die Messung vor der Entnahme von 6 systematischen Prostatastanzbiopsien. Patienten mit einem bioptisch gesicherten Prostatakarzinom und Patienten mit einer benignen Prostatahyperplasie wiesen vergleichbare Werte auf (14 258 pg/ml versus 14 658 pg/ml, St.Abw. 10 516 pg/ml). Bei 152 Patienten erfolgte die Messung 6–12 Monate nach radikaler Prostatektomie (Gruppe II), auch hier zeigte sich kein signifikanter Unterschied in der Plasmakonzentration bei Patienten mit einem postoperativen PSA-Progreß und postoperativ negativem PSA-Wert. Unsere Ergebnisse deuten an, daß die TGF-β1-Plasmakonzentration nicht als ein Marker für eine Unterscheidung von benignen oder malignen Prostataveränderungen eingesetzt werden kann.
    Notes: Summary Transforming growth factor-β1 (TGF-β1) is a pleiotrophic growth factor in carcinogenesis and regulars multiple cell functions. We wanted to evaluate the diagnostic meaning of TGF-β1 plasma levels in patients with a biopsy proven prostate cancer. The TGF-β1 blood level was analysed in 394 patients. In 242 patients (group I) the blood was taken before any prostate manipulation and biopsy. The TGF-β1 plasma concentrations were almost similar in the group of patients with a prostate cancer (n = 157) and patients with a benign prostate hyperplasia (n = 85; 14 258 pg/ml versus 14 658 pg/ml, SD 10 516 pg/ml). In 152 patients the blood was taken 6–12 months after radical prostatectomy (group II). There was no significant difference between the patients with a PSA-progress and without PSA-progress after. Our results suggest that TGF-β1 plasma levels can not be used to distinguish between patients with prostate cancer and benign prostate hyperplasia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001200050174
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  • 10
    Electronic Resource
    Electronic Resource
    Rapid detection of influenza A neuraminidase subtypes by cDNA amplification coupled to a simple DNA enzyme immunoassay (1994)
    Springer
    Archives of virology 139 (1994), S. 439-444 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A newly developed colorimetric method, DNA enzyme immunoassay (DEIA), was applied to the detection of neuraminidase subtypes N1 and N2 of influenza A viruses. Reverse transcription and polymerase chain reaction with universal primers were used for genomic amplification of H1N1, H2N2, and H3N2 strains. Following amplification, an aliquot of the PCR product was hybridized to biotinylated DNA sequences (N1/N2 probes) immobilized on microtiter wells. The hybridization event was revealed by monoclonal antibodies to double stranded DNA in a standard ELISA reaction. The assay described here was able to distinguish accurately between the two neuraminidase subtypes of human influenza A viruses. It is a simple and rapid method facilitating the handling of a large number of samples and therefore seems to be easily applicable to diagnostic laboratories.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01310805
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