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  • 1
    Electronic Resource
    Electronic Resource
    The wandering spleen (1983)
    Springer
    European journal of pediatrics 140 (1983), S. 112-115 
    Details
    ISSN: 1432-1076
    Keywords: Wandering spleen ; Abdominal pain ; Splenomegaly ; Ultrasonography ; Radionuclide liver-spleen scan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The article presents two cases of wandering spleen in the pediatric age group. Both patients were admitted for abdominal pain. In one, the onset was sudden and, on physical examination, a mass was felt in the left hypochondrium. In the other, it was the second episode and a firm mid-abdominal mass was found. The wandering spleen is a specific clinical syndrome which should be taken into account when an abdominal tumor is found. Ultrasonography and isotopic scan are very useful diagnostic tools The wandering spleen is caused by the absence of the splenorenal ligament which allows increased mobility of the splenic hilum. Both children underwent a splenectomy and made an uneventful recovery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441655
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  • 2
    Electronic Resource
    Electronic Resource
    Pulmonary plasma cell granuloma (1987)
    Springer
    European journal of pediatrics 146 (1987), S. 174-176 
    Details
    ISSN: 1432-1076
    Keywords: Plasma cell ; Granuloma ; Lung neoplasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two cases of pulmonary plasma cell granuloma in children are reported. The main features of this rare entity are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02343227
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  • 3
    Electronic Resource
    Electronic Resource
    Myxomatous degeneration of the mitral valve in a child with Turner syndrome and partial anomalous pulmonary venous return (1984)
    Springer
    European journal of pediatrics 141 (1984), S. 228-230 
    Details
    ISSN: 1432-1076
    Keywords: Turner syndrome ; Myxomatous degeneration ; Mitral valve replacement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This a report of myxomatous mitral valve degeneration in a child with Turner syndrome. The diagnosis was first suspected at 7 months of age. At 5 years of age, ultrasonic and angio-cardiographic confirmation prompted a successful mitral valve replacement with a Starr prosthesis. The child also had partial anomalous pulmonary venous return and a dysplastic right kidney. The child has remained well for 4 years after surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572766
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  • 4
    Electronic Resource
    Electronic Resource
    Fatal meningitis due to multi-resistant Haemophilus influenzae type b (1985)
    Springer
    European journal of pediatrics 144 (1985), S. 259-260 
    Details
    ISSN: 1432-1076
    Keywords: Meningitis ; Haemophilus influenzae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the case of a 3-month-old boy suffering from an acute bacterial meningitis due to a multi-resistant strain of Haemophilus influenzae type b. Also presented is our current strategy of treatment and chemoprophylaxis of Haemophilus influenzae meningitis in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00451955
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  • 5
    Electronic Resource
    Electronic Resource
    Gonadal Steroids and Bone Metabolism in Young Castrated Male Rats (2000)
    Springer
    Calcified tissue international 66 (2000), S. 470-475 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Dihydrotestosterone — Estradiol — Orchidectomy — Bone — Rat.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. At 45 days of age, 40 male Wistar rats were castrated, then randomly divided into four groups, S.C. injected for 60 days after surgery either with 17β-estradiol (E) 10 μg/kg BW/48 hours, progesterone (P) 140 μg/kg BW/48 hours, dihydrotestosterone (D) 2 μg/kg BW/48 hours, E + P + D same doses, or solvent alone (CX). Ten other rats were sham-operated (SH) and used as controls. Animals were put in balance to determine Ca and phosphorus (Pi) intestinal apparent absorption (IA Ca, IA Pi) and urinary pyridinium crosslinks excretion. Plasma was collected for measurement of intact-parathyroid hormone (PTH), calcitonin (CT), insulin-like growth factor I (IGF-I), 1,25 dihydroxyvitamin D (1,25(OH)2D), Ca, and Pi. Orchidectomy induced marked seminal vesicles atrophy and increased plasma CT, PTH, and Ca concentrations. IA Ca was significantly higher in P rats, however, neither castration nor any other treatment had significant effects. Orchidectomy decreased femoral length, dry weight, and Ca content, whereas E or D given alone or together with P improved endochondral growth and enhanced femoral Ca content. Again, bone mineral density was lowered by orchidectomy and reestablished by both E and EPD, even above SH values, this effect being more important at the metaphyseal levels. Urinary pyridinium cross-links excretion and plasma osteocalcin concentrations were higher in the CX animals than in the controls. Although E and D given alone did reduce both biochemical turnover markers, they showed additive effect when given together (EPD). In conclusion, in the young castrated male rat, E was more efficient than D for preventing bone loss, the most important effect being induced by a combination of E + P + D.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002230010094
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  • 6
    Electronic Resource
    Electronic Resource
    Treadmill running starting 3 months after orchidectomy restores femoral bone mass in rats (1999)
    Springer
    European journal of applied physiology 79 (1999), S. 251-259 
    Details
    ISSN: 1439-6327
    Keywords: Key words Bone ; Deoxypyridinoline ; Osteocalcin ; Rat ; Treadmill running
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The present study was designed to provide data on the effects on femoral bone of endurance training starting only 3 months after orchidectomy in rats. A total of 70 Wistar male rats were used at 8 weeks of age. On day 0 of the experiment, 10 rats were killed by cervical dislocation to be used as first controls. Among the 60 other animals, half was surgically castrated (CX) or sham operated (SH). On day 90, 10 CX and 10 SH were killed and used as intermediary controls (ICX and ISH). Among the other 20 CX and 20 SH, 10 within each group (CXE, SHE) were selected for treadmill running (60% maximal oxygen uptake, 1 h · day−1, 5 days · week−1 for 12 weeks). The 20 other rats were used as sedentary controls (CXR, SHR) and killed (as runners) on day 180. On day 90 femoral bone density (BMD) and mineral content (BMC) were lower in ICX than in ISH. On day 180 total femoral BMD was lower in CXR than in CXE. Simultaneously metaphyseal femoral BMD was lower in CXR than in CXE, SHR or SHE. Furthermore, at that time, no significant difference concerning BMD and BMC was observed between SHR and CXE. This would indicate that treadmill running starting only 3 months after orchidectomy is able to restore BMD and BMC to control values, mainly by inhibiting bone resorption (as shown by decreased urinary deoxypyridinoline excretion in CXE) without decreasing osteoblastic activity (evaluated by plasma osteocalcin concentration).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004210050503
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  • 7
    Electronic Resource
    Electronic Resource
    Does endurance running before orchidectomy prevent osteopenia in rats? (1999)
    Springer
    European journal of applied physiology 80 (1999), S. 344-352 
    Details
    ISSN: 1439-6327
    Keywords: Key words Endurance running ; Bone density ; Deoxypyridinoline ; Osteocalcin ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This experiment was performed to study the effects on femoral bone of endurance training performed during the 3 months before orchidectomy in rats which were then killed 90 days later. A total of 70 male Wistar rats were used at 8 weeks old. One day 0 of the experiment, 10 rats were killed by cervical dislocation and used as first controls. Among the 60 others, 30 were selected for treadmill running (60% maximal oxygen uptake, 1 h · day−1, 6 days · week−1 for 90 days). The 30 other rats remained at rest. On day 90, 10 exercised (IE) and resting (IR) rats were killed and used as intermediary controls. Among the 20 other animals of each group, 10 were surgically castrated (CXE, CXR) or 10 sham-operated (SHE, SHR) and killed on day 180. On day 90 femoral failure load (three-point bending test) was greater in IE than in IR. Simultaneously, the deoxypyridinolinuria was lower in IE than in IR. On day 180, femoral bones were thinner in CXR than in CXE. The lowest values for trabecular bone are in the distal femoral metaphysis were measured in CXE and CXR rats, but the value measured in CXE was no different from that measured in SHR. Simultaneously total femoral bone density was lower in CXR than in SHE, while no difference concerning femoral metaphyseal density was observed between CXE and SHR. These results confirmed that endurance running increased femoral bone growth and modelling and femoral trabecular area, and thereby peak bone mass, in 8-month-old male rats. In resting animals, castrated after the training period, androgen deficiency decreased femoral density, mineral content and trabecular area. This decrease was not observed in castrated but previously exercised rats. Thus, by increasing peak bone mass, it was considered that endurance training may have a preventive effect against orchidectomy-induced bone loss.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004210050602
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