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THE PRESENCE OF HYDROXYSTEROID DEHYDROGENASES IN MAMMALIAN SEBACEOUS STRUCTURES (1970)

MUIR, ANITA V. ; HODGINS, M. B. ; MILNE, J. A. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

British journal of dermatology 83 (1970), S. 0

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ISSN: 1365-2133

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Histochemical localization of HSD activity was investigated in sebaceous glands in skin of rat, guinea-pig, hamster and gerbil. Rat preputial gland, hamster costovertebral organ and gerbil ventral gland were also used. Rat skin and preputial gland showed HSD activity with DHA. oestradiol and 5-androstene-3β-16β-diol-3 methyl ether substrates while testosterone was poorly utilized in the 17β-HSD reaction.Guinea-pig lip sebaceous glands showed HSD activity with DHA, oestradiol, testosterone and 5-androstene-3β-16β-diol-3 methyl ether. None of the other tissues showed convincing HSD activity with any of the substrates used.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2133.1970.tb15702.x

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