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  • 1
    Electronic Resource
    Electronic Resource
    Experimental infection of Atlantic salmon, Salmo salar L., with infectious salmon anaemia virus: a histopathological study (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of fish diseases 23 (2000), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Recent reports of the isolation of infectious salmon anaemia virus (ISAV) from Atlantic salmon, Salmo salar L., affected by haemorrhagic kidney syndrome (HKS) suggest that ISAV can cause severe renal haemorrhage and necrosis in addition to well-known pathognomonic hepatocellular necrosis and haemorrhage. The prevalence of ISAV-induced pathognomonic renal HKS lesions and their correlation to pathognomonic hepatic lesions of infectious salmon anaemia (ISA) is not known. The present experimental infection of Atlantic salmon with a Canadian isolate of ISAV found that pathognomonic hepatic ISA lesions were present in 90.6% and pathognomonic renal HKS lesions in 78.1% of fish which died after the experimental challenge. Both pathognomonic hepatic ISA lesions and pathognomonic renal HKS lesions were found together in 65.6% of fish which died after ISAV challenge. The present study clearly demonstrates that ISAV can cause a very high prevalence of both HKS and ISA pathognomonic lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2761.2000.00203.x
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  • 2
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    Business and the Arts: A Productive Alliance Comes Under Stress (1982)
    Saranac Lake, N.Y., etc. : Periodicals Archive Online (PAO)
    Management Review. 71:10 (1982:Oct.) 63 
    Details
    ISSN: 0025-1895
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:7504-1982-071-10-000008
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  • 3
    Electronic Resource
    Electronic Resource
    Small bowel adaptation after intestinal resection in guinea pig with functional adaptation of vitamin B12 absorption (1973)
    Springer
    Digestive diseases and sciences 18 (1973), S. 576-582 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Although intestinal adaptation has been well-documented in the rat, the phenomenon has not been described in guinea pigs. The morphologic response of the ileum was therefore examined in female jejunectomized guinea pigs. Cellular hyperplasia was demonstrated by a twofold increase in villous height and DNA content per unit length of ileum 8 weeks after resection. A functional response to jejunectomy was confirmed by the significantly greater than normal absorption of a 50-ng oral dose of vitamin B12 (cyanocobalamin58Co) 5 weeks after resection. Attachment of cyanocobalamin57Co to the ileal mucosa was increased 8 weeks after operation, but uptake per milligram of mucosal DNA was decreased. The results indicate that ileal adaptation occurs after proximal resection in guinea pigs and that there is an associated increase in the capacity to absorb vitamin B12.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01072222
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  • 4
    Electronic Resource
    Electronic Resource
    Adaptive changes in vitamin B12 absorption in celiac disease and after proximal small-bowel resection in man (1975)
    Springer
    Digestive diseases and sciences 20 (1975), S. 835-840 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Resection of the proximal small bowel is known to cause mucosal hyperplasia and enhanced absorption in the ileum of experimental animals, but similar adaptive changes had not previously been studied in man. Since intrinsic-factor-bound vitamin B12 (IF-B12) absorption is confined to the ileum, as an index of ileal adaptation, we measured whole-body IF−58 Co B12 absorption in 24 control subjects, in 4 patients after proximal small-bowel resection, and in 9 patients with adult celiac disease (where mucosal damage is often limited to the proximal intestine and spares the ileum). Control subjects absorbed 20.4% (±1sd 6.2%) of the administered 5-μg dose of vitamin B12, while the corresponding 7-day retention values in patients with proximal resection (mean 42.3%; range 32–61%) and in 2 of the 9 celiac patients (44.1% and 54%, respectively), were above the normal range. The increased vitamin B12 absorption in these patients suggests that functional adaptation also occurs in the ileum in man. The results also illustrate the application of a newly developed whole-body counting technique to study vitamin B12 absorption in man.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01070951
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    Paper (German National Licenses)
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